Zobrazeno 1 - 10
of 395
pro vyhledávání: '"John D, West"'
Autor:
John D West, Clare A Everett
Publikováno v:
Reproduction and Fertility, Vol 3, Iss 2, Pp R66-R90 (2022)
Some human preimplantation embryos are chromosomally mosaic. For technical reasons, estimates of the overall frequency vary widely from 90% and the true frequency remains unknown. Aneuploid/diploid and aneuploid/ aneuploid mosaics typically arise dur
Externí odkaz:
https://doaj.org/article/1fcb0f16263e4299a007eda48c3f9a54
Autor:
Qiuting Wen, Sourajit M. Mustafi, Junjie Li, Shannon L. Risacher, Eileen Tallman, Steven A. Brown, John D. West, Jaroslaw Harezlak, Martin R. Farlow, Frederick W. Unverzagt, Sujuan Gao, Liana G. Apostolova, Andrew J. Saykin, Yu‐Chien Wu
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 576-587 (2019)
Abstract Introduction Diffusion magnetic resonance imaging may allow for microscopic characterization of white matter degeneration in early stages of Alzheimer's disease. Methods Multishell Diffusion magnetic resonance imaging data were acquired from
Externí odkaz:
https://doaj.org/article/22df8fb953ba44ed9c38851200b863c6
Autor:
Evgeny J. Chumin, Shannon L. Risacher, John D. West, Liana G. Apostolova, Martin R. Farlow, Brenna C. McDonald, Yu-Chien Wu, Andrew J. Saykin, Olaf Sporns
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102726- (2021)
Understanding the interrelationships of clinical manifestations of Alzheimer’s disease (AD) and functional connectivity (FC) as the disease progresses is necessary for use of FC as a potential neuroimaging biomarker. Degradation of resting-state ne
Externí odkaz:
https://doaj.org/article/f92778b59c034ca8892c8d3d89730ae7
Autor:
Shannon L. Risacher, John D. West, Rachael Deardorff, Sujuan Gao, Martin R. Farlow, Jared R. Brosch, Liana G. Apostolova, Thomas W. McAllister, Yu‐Chien Wu, William J. Jagust, Susan M. Landau, Michael W. Weiner, Andrew J. Saykin, for the Alzheimer's Disease Neuroimaging Initiative#
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Head injuries (HI) are a risk factor for dementia, but the underlying etiology is not fully known. Understanding whether tau might mediate this relationship is important. Methods Cognition and tau deposition were compared betwee
Externí odkaz:
https://doaj.org/article/54cf32b657e24c65976b025d4a854354
Autor:
Natalie J. Dorà, Martine Manuel, Dirk-Jan Kleinjan, David J. Price, J. Martin Collinson, Robert E. Hill, John D. West
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-8 (2018)
Abstract Objective The corneas of heterozygous Pax6 +/− mice develop abnormally and deteriorate further after birth but it is not known whether the postnatal deterioration is predetermined by abnormal development. Our objective was to identify whet
Externí odkaz:
https://doaj.org/article/b408ec98da0b4083aacabda28374eb4e
Publikováno v:
Stem Cell Research, Vol 30, Iss , Pp 1-11 (2018)
The use of mice that are mosaic for reporter gene expression underlies many lineage-tracing studies in stem cell biology. For example, using mosaic LacZ reporter mice, it was shown that limbal epithelial stem cells (LESCs) around the periphery of the
Externí odkaz:
https://doaj.org/article/a9a5e2e44a9b43e8bc70e873570c5444
Autor:
John D. West, Pin-Chi Tang, Clare A. Everett, Gillian E. MacKay, Jean H. Flockhart, Margaret A. Keighren
Publikováno v:
Biology Open, Vol 8, Iss 5 (2019)
The composition of adult mouse aggregation chimaeras is much more variable than X-inactivation mosaics. An early theoretical model proposed that almost all the extra variation in chimaeras arises, before X-inactivation occurs, by spatially constraine
Externí odkaz:
https://doaj.org/article/e473a438b43543969890352a60f48340
Autor:
Joey A. Contreras, Andrea Avena-Koenigsberger, Shannon L. Risacher, John D. West, Eileen Tallman, Brenna C. McDonald, Martin R. Farlow, Liana G. Apostolova, Joaquín Goñi, Mario Dzemidzic, Yu-Chien Wu, Daniel Kessler, Lucas Jeub, Santo Fortunato, Andrew J. Saykin, Olaf Sporns
Publikováno v:
NeuroImage: Clinical, Vol 22, Iss , Pp - (2019)
Alzheimer's disease is considered a disconnection syndrome, motivating the use of brain network measures to detect changes in whole-brain resting state functional connectivity (FC). We investigated changes in FC within and among resting state network
Externí odkaz:
https://doaj.org/article/344e3795dbed4b25886c116e42330129
Publikováno v:
Biology Open, Vol 5, Iss 5, Pp 596-610 (2016)
The mouse Gpi1 gene encodes the glycolytic enzyme glucose phosphate isomerase. Homozygous Gpi1−/− null mouse embryos die but a previous study showed that some homozygous Gpi1−/− null cells survived when combined with wild-type cells in fetal
Externí odkaz:
https://doaj.org/article/b98d31fc2a554589b960369fbceae31d
Autor:
Tugce Duran, Ellen Woo, Diana Otero, Shannon L. Risacher, Eddie Stage, Apoorva B. Sanjay, Kwangsik Nho, John D. West, Meredith L. Phillips, Naira Goukasian, Kristy S. Hwang, Liana G. Apostolova
Publikováno v:
Brain Imaging Behav
Metacognitive deficits affect Alzheimer’s disease (AD) patient safety and increase caregiver burden. The brain areas that support metacognition are not well understood. 112 participants from the Imaging and Genetic Biomarkers for AD (ImaGene) study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08cd666dfd08001c7c17363c6d9bd6b4
https://doi.org/10.1007/s11682-021-00627-0
https://doi.org/10.1007/s11682-021-00627-0