Zobrazeno 1 - 10
of 246
pro vyhledávání: '"John D, Brennan"'
Autor:
M. Monsur Ali, Michael G. Wolfe, Manali Mukherjee, Katherine Radford, Zil Patel, Dawn White, Julijana Milojevic, Alfredo Capretta, Parameswaran Nair, John D. Brennan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Eosinophils are granulocytes that play a significant role in the pathogenesis of asthma and other airway diseases. Directing patient treatment based on the level of eosinophilia has been shown to be extremely effective in reducing exacerbati
Externí odkaz:
https://doaj.org/article/1f71906723564805bc93196351e347f6
Autor:
Dawn White, Jimmy Gu, Catherine-Jean Steinberg, Deborah Yamamura, Bruno J. Salena, Cynthia Balion, Carlos D. M. Filipe, Alfredo Capretta, Yingfu Li, John D. Brennan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract Saliva is an attractive sample for coronavirus disease 2019 testing due its ease of collection and amenability to detect viral RNA with minimal processing. Using a direct-to-RT-PCR method with saliva self-collected from confirmed COVID-19 po
Externí odkaz:
https://doaj.org/article/46bfc93864944ba998038369dda41123
Autor:
Kristen Abels, Elizabeth M. Salvo-Halloran, Dawn White, Monsur Ali, Nisha R. Agarwal, Vincent Leung, Muntakim Ali, Mariam Sidawi, Alfredo Capretta, John D. Brennan, Jake Nease, Carlos D. M. Filipe
Publikováno v:
ACS Omega, Vol 6, Iss 34, Pp 22439-22446 (2021)
Externí odkaz:
https://doaj.org/article/f161862e305c4a938cda0b1276d14725
Autor:
Jiuxing Li, Zijie Zhang, Jimmy Gu, Ryan Amini, Alexandria G. Mansfield, Jianrun Xia, Dawn White, Hannah D. Stacey, Jann C. Ang, Gurpreet Panesar, Alfredo Capretta, Carlos D. M. Filipe, Karen Mossman, Bruno J. Salena, Jonathan B. Gubbay, Cynthia Balion, Leyla Soleymani, Matthew S. Miller, Deborah Yamamura, John D. Brennan, Yingfu Li
Publikováno v:
Journal of the American Chemical Society. 144:23465-23473
Our previously discovered monomeric aptamer for SARS-CoV-2 (MSA52) possesses a universal affinity for COVID-19 spike protein variants but is ultimately limited by its ability to bind only one subunit of the spike protein. The symmetrical shape of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affd2106019271cf5da112035bcaeb55
https://doi.org/10.1021/jacs.2c09870
https://doi.org/10.1021/jacs.2c09870
Autor:
Jimmy Gu, Amal Mathai, Connor Nurmi, Dawn White, Gurpreet Panesar, Deborah Yamamura, Cynthia Balion, Jonathan Gubbay, Karen Mossman, Alfredo Capretta, Bruno J. Salena, Leyla Soleymani, Carlos D. M. Filipe, John D. Brennan, Yingfu Li
Publikováno v:
Chemistry – A European Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1aced955373ff62b1c914cb48f1517f
https://doi.org/10.1002/chem.202300075
https://doi.org/10.1002/chem.202300075
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
DNA nanostructures with interlocked topologies will tend to display different behaviour to the linear counterparts. Here, the authors show a DNA catenane that is inactive for rolling circle amplification but is activated upon cleavage of one ring, an
Externí odkaz:
https://doaj.org/article/ad34805213f748618cc14875c581add5
Publikováno v:
Chemical Science. 13:6496-6501
Terminal deoxynucleotidyl transferase (TdT) catalyzes template-independent DNA synthesis in a well-controllable mode on paper, allowing absolute quantification of polymetric labeling of a single 3′-OH present on genomic DNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7d24939aad9e153875dd9b5bc670b51
https://doi.org/10.1039/d1sc04268h
https://doi.org/10.1039/d1sc04268h
Autor:
Zijie Zhang, Jiuxing Li, Ryan Amini, Alexandria Mansfield, Jimmy Gu, Jianrun Xia, John D. Brennan, Yingfu Li
Publikováno v:
Analysis & Sensing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cd8274afa5a4157c3760a224bfd990
https://doi.org/10.1002/anse.202300001
https://doi.org/10.1002/anse.202300001
Autor:
Leyla Soleymani, Bruno J. Salena, Jimmy Gu, Yingfu Li, Karen L. Mossman, Jiuxing Li, John D. Brennan, Zijie Zhang, Dawn White, Matthew S. Miller, Cynthia Balion, Hannah D. Stacey, Deborah Yamamura, Jann C. Ang, Alfredo Capretta, Richa Pandey, Carlos D. M. Filipe, Catherine-Jean Steinberg
Publikováno v:
Angewandte Chemie (International Ed. in English)
We report a simple and rapid saliva‐based SARS‐CoV‐2 antigen test that utilizes a newly developed dimeric DNA aptamer, denoted as DSA1N5, that specifically recognizes the spike proteins of the wildtype virus and its Alpha and Delta variants wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea4fe8a2a33c16c96bba8873f526940
https://doi.org/10.1002/anie.202110819
https://doi.org/10.1002/anie.202110819
Autor:
Yingfu Li, Leyla Soleymani, Dingran Chang, Meng Liu, Carlos D. M. Filipe, Sandy Zakaria, Sahar Esmaeili Samani, John D. Brennan, Yangyang Chang
Publikováno v:
Accounts of Chemical Research. 54:3540-3549
ConspectusPathogens have long presented a significant threat to human lives, and hence the rapid detection of infectious pathogens is vital for improving human health. Current detection methods lack the means to detect infectious pathogens in a simpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7528782736039d214edcf35bb7d456d5
https://doi.org/10.1021/acs.accounts.1c00355
https://doi.org/10.1021/acs.accounts.1c00355