Zobrazeno 1 - 10
of 52
pro vyhledávání: '"John Counsell"'
Autor:
Maximillian Woodall, Robert Tarran, Rhianna Lee, Hafssa Anfishi, Stella Prins, John Counsell, Paola Vergani, Stephen Hart, Deborah Baines
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 593-605 (2023)
Class Ia/b cystic fibrosis transmembrane regulator (CFTR) variants cause severe lung disease in 10% of cystic fibrosis (CF) patients and are untreatable with small-molecule pharmaceuticals. Genetic replacement of CFTR offers a cure, but its effective
Externí odkaz:
https://doaj.org/article/4971911eb5dc42e3a35665650cbd041d
Autor:
Faisal Nawaz, Daniel Martin Simadibrata, Vikas Bansal, Ramesh Adhikari, Mariam Elsaban, Rahul Kashyap, Priyadarshini Bhattacharjee, Jorge Salluh, Hassan Dawood Alli, Joanna Lee, Dattatreya Mukherjee, Tanja Kovačević, Mohammad Yasir Essar, Christos Tsagkaris, Genesis Camacho-Leon, Faizan Ahmad, Akshat Banga, Hans Mautong, Razan Alamoudi, Umme Habiba Faisal, Gaurang Bhatt, Tanya Amal, Ayushi Mendiratta, Bhaswanth Bollu, L V Simhachalam Kutikuppala, Ivan Huespe, Aisha Khalid, Mohammed Amir Rais, Alisha Lakhani, Piyush Garg, Harsha Pattnaik, Raghu Gandhi, Ramesh Pandit, Pierre Ciza N, Nimsi Barrios, Kelly Meza, Susan Okonkwo, Amuza Dhabuliwo, Hafeez Hamza, Arash Nemat, Anne Kampa, Rakhtan K Qasba, Pranjal Sharma, Taru Dutt, Pratikkumar Vekaria, Faisal A Nawaz, Salim Surani, Divya Randhawa, Rakhtan Qasba, Trupti Pandit, Ayesha Khalid, Ravina Verma, Kush Shah, John Counsell, Naresh Dasari, Melissa Schlenker, Raghavendra Tirupathi, Gowthami Sai Jagirdhar, Nancy Nagib, Benjamin Schlenker, Taha Mansoor, N Pierre Ciza, Leydi Del Lema, Susan Sheila, Bello Saifullah Muhammad, Barakat Kolawole, L V Kutikuppala, Keidy Zamora, Bikona Ghosh, Sama Soliman, Zainab Ayoob, Lina Almahmoud, Dohha Mohammed, Oyindamola Obadare, Era Mae Ramirez, Kalloush Shahed, Mohammed Yasir Essar, Sarya Swed, Temaa Alklani, Ishimwe Florent, Goodluck Nchasi, Daren Poh How, Mohamed Elfagieh, Moath Almekhlafi, Reshon Hadmon, Anasonye Emmanuel, Yosra Magdi Makki, Rodrigue Ndabashinze, Hussein Dawoud, Dimitrios Kantas, Daniella Myriam Pierre, Zeynep Pelin Orhan, Usama Oguz, Hedys Selene Mogollón, Ramesha Remy, Marija Vukoja, Srdjan Gavrilovic, Alicja Rydzewska Rosolowska, Umme Faisal, Franz Lopez, Salem Ramirez, Lisdamys Morera Gonzalez, Mohammed Alkawak, Marco Antonio Villar, Kelly Maza, Shehu Bledi, Jonida Naska
Publikováno v:
BMJ Global Health, Vol 8, Iss 9 (2023)
Objective To provide insights into the nature, risk factors, impact and existing measures for reporting and preventing violence in the healthcare system. The under-reporting of violence against healthcare workers (HCWs) globally highlights the need f
Externí odkaz:
https://doaj.org/article/db86c181e00f4b7b8a95f430385f21fc
Autor:
Jinhong Meng, Marc Moore, John Counsell, Francesco Muntoni, Linda Popplewell, Jennifer Morgan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 491-507 (2022)
Duchenne muscular dystrophy (DMD) is a muscle wasting disorder caused by mutations in the DMD gene. Restoration of full-length dystrophin protein in skeletal muscle would have therapeutic benefit, but lentivirally mediated delivery of such a large ge
Externí odkaz:
https://doaj.org/article/19682bbce5954b47a33dacda7ecb08ec
Autor:
Veronica Pini, Virginie Mariot, Julie Dumonceaux, John Counsell, Helen C. O’Neill, Sarah Farmer, Francesco Conti, Francesco Muntoni
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Among the mutations arising in the DMD gene and causing Duchenne Muscular Dystrophy (DMD), 10–15% are multi-exon duplications. There are no current therapeutic approaches with the ability to excise large multi-exon duplications, leaving th
Externí odkaz:
https://doaj.org/article/f9737f98c68e4dc1b4e5032db9cf3319
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7168 (2020)
Background: We are developing a novel therapy for Duchenne muscular dystrophy (DMD), involving the transplantation of autologous, skeletal muscle-derived stem cells that have been genetically corrected to express dystrophin. Dystrophin is normally ex
Externí odkaz:
https://doaj.org/article/06f26ed9600347c0868d8b4552194f16
Autor:
Maximillian Woodall, Robert Tarran, Rhianna Lee, Hafssa Anfishi, Stella Prins, John Counsell, Paola Vergani, Stephen Hart, Deborah Baines
Class Ia/b CFTR variants cause severe cystic fibrosis (CF) lung disease in ~10% of CF patients and are untreatable with small molecule pharmaceuticals. Genetic replacement strategies offer a potential cure for all patients but so far, have displayed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67ff1c9c0441778ab010737a546083a6
https://doi.org/10.1101/2022.08.10.503368
https://doi.org/10.1101/2022.08.10.503368
Publikováno v:
The International Journal of Design Education. 15:75-89
Autor:
Veronica Pini, Virginie Mariot, Julie Dumonceaux, John Counsell, Helen C. O’Neill, Sarah Farmer, Francesco Conti, Francesco Muntoni
Publikováno v:
Scientific reports. 12(1)
Among the mutations arising in the DMD gene and causing Duchenne Muscular Dystrophy (DMD), 10–15% are multi-exon duplications. There are no current therapeutic approaches with the ability to excise large multi-exon duplications, leaving this patien
Publikováno v:
Proceedings of the 22nd International Conference on Engineering and Product Design Education.
Some HE institutions restrict students’ choice of where to work. These restrictions, in addition to students being in shared non-ideal environs, such as institutional spaces, reduce their personal control over the physical factors of such spaces. T
Building Information Modelling (BIM) is being debated, tested and implemented wherever you look across the built environment sector. This book is about Heritage Building Information Modelling (HBIM), which necessarily differs from the commonplace app