Zobrazeno 1 - 10
of 309
pro vyhledávání: '"John Cijiang, He"'
Autor:
Philip Kam-Tao Li, Jack Kit-Chung Ng, Guang-yan Cai, Wei Chen, Kai Ming Chow, Stanley Fan, John Cijiang He, Lai Seong Hooi, York Pei, Boon Wee Teo, Muh Geot Wong, I-Wen Wu, Jianhui Zhou, Na Tian, Zhiming Ye, Xueqing Yu
Publikováno v:
Kidney Diseases, Pp 1-14 (2024)
Background: Chronic kidney disease (CKD) continues to be a significant global public health issue. The escalating burden of CKD is probably driven by the aging population and the rising prevalence of diabetes. CKD not only adversely impacts an indivi
Externí odkaz:
https://doaj.org/article/0ea1939371be403fa1ed2d51a1614bde
Publikováno v:
Kidney Diseases, Pp 1-9 (2024)
Background: Podocyte loss occurs in both primary and secondary glomerular diseases, leading to the progression of kidney disease. A large body of evidence suggests that apoptosis and detachment are the mechanisms mediating the reduction in podocyte n
Externí odkaz:
https://doaj.org/article/72ecd1bb7ddc4a38918a43c8a2d1864f
Autor:
Lu Zhang, Zhengying Fang, Qingqing Zhu, Shumin Yang, Jia Fu, Zeguo Sun, Geming Lu, Chengguo Wei, Zhi Zhang, Kyung Lee, Yifei Zhong, Ruijie Liu, John Cijiang He
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Cholesterol 25‐hydroxylase (CH25H), an enzyme involved in cholesterol metabolism, regulates inflammatory responses and lipid metabolism. However, its role in kidney disease is not known. The author found that CH25H transcript is expressed
Externí odkaz:
https://doaj.org/article/05a8b26a0fdb4ba1af8082d0997099a8
Autor:
Quan Hong, Ou Li, Wei Zheng, Wen-zhen Xiao, Lu Zhang, Di Wu, Guang-yan Cai, John Cijiang He, Xiang-mei Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/fa3ce4e998bd41af8986ea616920486d
Publikováno v:
Glomerular Diseases, Vol 3, Iss 1, Pp 148-154 (2023)
Background: The association between viral infections and glomerular diseases, commonly known as “viral glomerulopathies,” has been described in various clinical scenarios for decades. Despite advancements in diagnostic tools, it remains challengi
Externí odkaz:
https://doaj.org/article/b00a23bd6d2847689a0a59e4436c0cab
Autor:
Man Chen, Madhav C. Menon, Wenlin Wang, Jia Fu, Zhengzi Yi, Zeguo Sun, Jessica Liu, Zhengzhe Li, Lingyun Mou, Khadija Banu, Sui-Wan Lee, Ying Dai, Nanditha Anandakrishnan, Evren U. Azeloglu, Kyung Lee, Weijia Zhang, Bhaskar Das, John Cijiang He, Chengguo Wei
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Renal inflammation and fibrosis are the common pathways leading to progressive chronic kidney disease (CKD). We previously identified hematopoietic cell kinase (HCK) as upregulated in human chronic allograft injury promoting kidney fibrosis;
Externí odkaz:
https://doaj.org/article/e689bc4de88348f390574b2a526d79ac
Autor:
Ishan Paranjpe, Pushkala Jayaraman, Chen-Yang Su, Sirui Zhou, Steven Chen, Ryan Thompson, Diane Marie Del Valle, Ephraim Kenigsberg, Shan Zhao, Suraj Jaladanki, Kumardeep Chaudhary, Steven Ascolillo, Akhil Vaid, Edgar Gonzalez-Kozlova, Justin Kauffman, Arvind Kumar, Manish Paranjpe, Ross O. Hagan, Samir Kamat, Faris F. Gulamali, Hui Xie, Joceyln Harris, Manishkumar Patel, Kimberly Argueta, Craig Batchelor, Kai Nie, Sergio Dellepiane, Leisha Scott, Matthew A. Levin, John Cijiang He, Mayte Suarez-Farinas, Steven G. Coca, Lili Chan, Evren U. Azeloglu, Eric Schadt, Noam Beckmann, Sacha Gnjatic, Miram Merad, Seunghee Kim-Schulze, Brent Richards, Benjamin S. Glicksberg, Alexander W. Charney, Girish N. Nadkarni
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-10 (2023)
Abstract Background Acute kidney injury (AKI) is a known complication of COVID-19 and is associated with an increased risk of in-hospital mortality. Unbiased proteomics using biological specimens can lead to improved risk stratification and discover
Externí odkaz:
https://doaj.org/article/a59378e85e3b46de854114917b9da8cd
Autor:
Zeguo Sun, Zhongyang Zhang, Khadija Banu, Ian W. Gibson, Robert B. Colvin, Zhengzi Yi, Weijia Zhang, Bony De Kumar, Anand Reghuvaran, John Pell, Thomas D. Manes, Arjang Djamali, Lorenzo Gallon, Philip J. O’Connell, John Cijiang He, Jordan S. Pober, Peter S. Heeger, Madhav C. Menon
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLAs) contribute to kidney allograft loss, but the mechanisms remain unclear, specifically for intronic mismatches. We quantified non-HLA mismatches at variant-, gene-, and genome-
Externí odkaz:
https://doaj.org/article/1062a57a1df84d2eb0cec1a6f8b62c10
Autor:
Kristin Meliambro, Yanfeng Yang, Marina de Cos, Estefania Rodriguez Ballestas, Caroline Malkin, Jonathan Haydak, John R. Lee, Fadi Salem, Laura H. Mariani, Ronald E. Gordon, John M. Basgen, Huei Hsun Wen, Jia Fu, Evren U. Azeloglu, John Cijiang He, Jenny S. Wong, Kirk N. Campbell
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Despite recent progress in the identification of mediators of podocyte injury, mechanisms underlying podocyte loss remain poorly understood, and cell-specific therapy is lacking. We previously reported that kidney and brain expressed protein (KIBRA),
Externí odkaz:
https://doaj.org/article/427bdc10103645eb8f284f1c9af46d1b
Publikováno v:
Kidney Diseases, Vol 8, Iss 1, Pp 1-12 (2021)
Kidney disease is a major complication of viral infection, which can cause both acute and chronic kidney diseases via different mechanisms such as immune-mediated injury, kidney cell injury from a direct viral infection, systemic effects, and antivir
Externí odkaz:
https://doaj.org/article/d35022ac981144c39ee8f1bf1cac04df