Zobrazeno 1 - 10
of 17
pro vyhledávání: '"John Cheriyan"'
Autor:
John Cheriyan, Patrick L. Sheets
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Cellular and synaptic mechanisms underlying how chronic pain induces maladaptive alterations to local circuits in the medial prefrontal cortex (mPFC), while emerging, remain unresolved. Consistent evidence shows that chronic pain attenuates
Externí odkaz:
https://doaj.org/article/6c2edada9b934e1b970301dd80e2c312
Publikováno v:
EAI Endorsed Transactions on Creative Technologies, Vol 8, Iss 26 (2021)
This paper introduces the idea of Indoor Navigation using Augmented Reality. With the increase in complex building structures, people of different age may find it difficult to navigate within such structures. This paper provides a solution for this t
Externí odkaz:
https://doaj.org/article/6243b506b8ef4436a8b5ced0e5e7a705
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81405 (2013)
Three members of a family of small neurotoxic peptides from the venom of Conus parius, conantokins (Con) Pr1, Pr2, and Pr3, function as antagonists of N-methyl-D-aspartate receptors (NMDAR). We report structural characterizations of these synthetic p
Externí odkaz:
https://doaj.org/article/242d700ab10c4b8fa33b63aa9acd145b
Autor:
John Cheriyan, Archana G Mohanan, Pradeep K Kurup, Madhavan Mayadevi, Ramakrishnapillai Vyomakesannair Omkumar
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45064 (2012)
Interaction of GluN2B subunit of N-methyl-D-aspartate receptor with calcium/calmodulin dependent protein kinase II (CaMKII) is critical for the induction of long term potentiation at hippocampal CA3-CA1 synapses. We have previously reported that CaMK
Externí odkaz:
https://doaj.org/article/974d101ec05b46c9be234e1451b1703c
Autor:
John Cheriyan, Parimal Kumar, Madhavan Mayadevi, Avadhesha Surolia, Ramakrishnapillai V Omkumar
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e16495 (2011)
Calcium/calmodulin dependent protein kinase II (CaMKII) is implicated to play a key role in learning and memory. NR2B subunit of N-methyl-D-aspartate receptor (NMDAR) is a high affinity binding partner of CaMKII at the postsynaptic membrane. NR2B bin
Externí odkaz:
https://doaj.org/article/8c77390c32d54a7c90184fbc599e61c0
Publikováno v:
EAI Endorsed Transactions on Creative Technologies, Vol 8, Iss 26 (2021)
This paper introduces the idea of Indoor Navigation using Augmented Reality. With the increase in complex building structures, people of different age may find it difficult to navigate within such structures. This paper provides a solution for this t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de900391df46b1a9056725573c59ec5
https://eudl.eu/pdf/10.4108/eai.17-2-2021.168718
https://eudl.eu/pdf/10.4108/eai.17-2-2021.168718
Autor:
Patrick L. Sheets, John Cheriyan
Publikováno v:
Molecular Brain
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Cellular and synaptic mechanisms underlying how chronic pain induces maladaptive alterations to local circuits in the medial prefrontal cortex (mPFC), while emerging, remain unresolved. Consistent evidence shows that chronic pain attenuates activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47208c15c9145728bdcc9c10db9ee10a
http://europepmc.org/articles/PMC7325111
http://europepmc.org/articles/PMC7325111
Altered Excitability and Local Connectivity of mPFC-PAG Neurons in a Mouse Model of Neuropathic Pain
Autor:
John Cheriyan, Patrick L. Sheets
Publikováno v:
The Journal of Neuroscience. 38:4829-4839
The medial prefrontal cortex (mPFC) plays a major role in both sensory and affective aspects of pain. There is extensive evidence that chronic pain produces functional changes within the mPFC. However, our understanding of local circuit changes to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfdadc3116fd2eb706f60208f8321ee
https://doi.org/10.1523/jneurosci.2731-17.2018
https://doi.org/10.1523/jneurosci.2731-17.2018
The N-Methyl-D-Aspartate Receptors (NMDARs) are heteromeric cation channels involved in learning, memory, and synaptic plasticity, and their dysregulation leads to various neurodegenerative disorders. Recent evidence has shown that apart from the Glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eba4a778682ef0e9692c0356990cb5d
https://europepmc.org/articles/PMC5312704/
https://europepmc.org/articles/PMC5312704/
Publikováno v:
Biochemistry
NMDA receptors (NMDAR) are voltage- and glutamate-gated heteromeric ion channels found at excitatory neuronal synapses, the functions of which are to mediate the mechanisms of brain plasticity and, thereby, its higher order functions. In addition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e27a3afe11bd07a98a394bcdb52091d
https://pubmed.ncbi.nlm.nih.gov/25544544
https://pubmed.ncbi.nlm.nih.gov/25544544