Zobrazeno 1 - 10
of 22
pro vyhledávání: '"John Casement"'
Autor:
Shaymaa Sadeq, Suwalak Chitcharoen, Surar Al-Hashimi, Somruthai Rattanaburi, John Casement, Andreas Werner
Publikováno v:
Cells, Vol 13, Iss 3, p 226 (2024)
Endogenous double-stranded RNA has emerged as a potent stimulator of innate immunity. Under physiological conditions, endogenous dsRNA is maintained in the cell nucleus or the mitochondria; however, if protective mechanisms are breached, it leaches i
Externí odkaz:
https://doaj.org/article/3cccf3c8ef6449b0b9a96989850bbe6c
Autor:
Chalermsin Permtermsin, H Lalchungnunga, Sirintra Nakjang, John Casement, Laura Frances Ogle, Helen L. Reeves, Gordon Strathdee, Ruchi Shukla
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6387 (2023)
Hepatocellular carcinoma (HCC), the most common type of liver cancer, has very poor outcomes. Current therapies often have low efficacy and significant toxicities. Thus, there is a critical need for the development of novel therapeutic approaches for
Externí odkaz:
https://doaj.org/article/8a27b2d34f6b4623a5e32c190da03e2d
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionPrimary Sjögren’s Syndrome (PSS) is a chronic disease characterised by symptoms of oral and ocular dryness, pain, fatigue, anxiety and depression. PSS patients can be subclassified by the pattern of severity of these five key symptoms
Externí odkaz:
https://doaj.org/article/8cbc39419728440d96825548278f124a
Autor:
Vinciane Saint-Criq, Livia Delpiano, John Casement, Jennifer C. Onuora, JinHeng Lin, Michael A. Gray
Publikováno v:
Cells, Vol 9, Iss 9, p 2137 (2020)
In vitro cultures of primary human airway epithelial cells (hAECs) grown at air–liquid interface have become a valuable tool to study airway biology under normal and pathologic conditions, and for drug discovery in lung diseases such as cystic fibr
Externí odkaz:
https://doaj.org/article/9c281aa14b8e45eeb9578b34bac254eb
Autor:
Aurelie Guyet, Martyn Dade-Robertson, Anil Wipat, John Casement, Wendy Smith, Helen Mitrani, Meng Zhang
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200660 (2018)
Hydrostatic pressure is an important physical stimulus which can cause various responses in bacterial cells. The survival and cellular processes of Escherichia coli under hydrostatic pressures between 10 MPa and 110 MPa have been studied. However, un
Externí odkaz:
https://doaj.org/article/1f2b956626fc4d16a5edbcfa75fdfec2
Autor:
Bassier Zadran, Praveen Dhondurao Sudhindar, Daniel Wainwright, Yvonne Bury, Saimir Luli, Rachel Howarth, Misti Vanette McCain, Robyn Watson, Hannah Huet, Fanni Palinkas, Rolando Berlinguer-Palmini, John Casement, Derek A. Mann, Fiona Oakley, John Lunec, Helen Reeves, Geoffrey J. Faulkner, Ruchi Shukla
Publikováno v:
British Journal of Cancer. 128:1236-1248
Background Molecular characterisation of hepatocellular carcinoma (HCC) is central to the development of novel therapeutic strategies for the disease. We have previously demonstrated mutagenic consequences of Long-Interspersed Nuclear Element-1 (LINE
Autor:
Ron Kremer, Syed Mohib Raza, Fabiola Eto, John Casement, Christian Atallah, Sarah Finer, Dennis Lendrem, Michael Barnes, Nick J Reynolds, Paolo Missier
Publikováno v:
2022 IEEE International Conference on Big Data (Big Data).
Autor:
Sarah J Rice, Abby Brumwell, Julia Falk, Yulia S Kehayova, John Casement, Eleanor Parker, Ines M J Hofer, Colin Shepherd, John Loughlin
Publikováno v:
Human Molecular Genetics.
Osteoarthritis (OA) is a polygenic disease of older people resulting in the breakdown of cartilage within articular joints. Although it is a leading cause of disability, there are no disease-modifying therapies. Evidence is emerging to support the or
Autor:
Sarah Rice, Abby Brumwell, Julia Falk, Yulia Kehayova, John Casement, Eleanor Parker, Ines Hofer, Colin Shepherd, John Loughlin
Osteoarthritis (OA) is a polygenic disease of older people resulting in the breakdown of cartilage within articular joints. Although a leading cause of disability, there are no disease-modifying therapies. Evidence is emerging to support the origins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8509678ee4d1a66587a38fec574b5d03
https://doi.org/10.21203/rs.3.rs-2056256/v1
https://doi.org/10.21203/rs.3.rs-2056256/v1