Zobrazeno 1 - 10
of 102
pro vyhledávání: '"John Carbon"'
Publikováno v:
Proceedings of the National Academy of Sciences. 103:14877-14882
In the pathogenic yeast Candida albicans , the 3-kb centromeric DNA regions ( CEN ) of each of the eight chromosomes have different and unique DNA sequences. The centromeric histone CaCse4p (CENP-A homolog) occurs only within these 3-kb CEN regions t
Autor:
John Carbon, Tanja Stoyan
Publikováno v:
Eukaryotic Cell. 3:1154-1163
The human pathogenic yeast Candida glabrata is the second most common Candida pathogen after Candida albicans , causing both bloodstream and mucosal infections. The centromere ( CEN ) DNA of C. glabrata ( CgCEN ), although structurally very similar t
Autor:
Hye-Joo Yoon, John Carbon
Publikováno v:
Proceedings of the National Academy of Sciences. 96:13208-13213
Yeast two-hybrid and genetic interaction screens indicate that Bir1p, a yeast protein containing phylogenetically conserved antiapoptotic repeat domains called baculovirus inhibitor of apoptosis repeats (BIRs), is involved in chromosome segregation e
Publikováno v:
Molecular and Cellular Biology. 19:7461-7472
In budding yeast (Saccharomyces cerevisiae), the majority of box H/ACA small nucleolar RNPs (snoRNPs) have been shown to direct site-specific pseudouridylation of rRNA. Among the known protein components of H/ACA snoRNPs, the essential nucleolar prot
Autor:
C. Erickson, John Carbon, R. Buchholz, S. J. Poole, B. Phillips, John R. Merriam, C. Cadwell, A. N. Billin
Publikováno v:
Molecular and General Genetics MGG. 260:20-29
The Cbf5 protein of Saccharomyces cerevisiae was originally identified as a low-affinity centromeric DNA-binding protein, and chf5 mutants have a defect in rRNA synthesis. A closely related protein from mammals, NAP57, is a nucleolar protein that coi
Publikováno v:
Molecular and Cellular Biology. 17:6175-6183
Yeast Cbf5p was originally isolated as a low-affinity centromeric DNA binding protein (W. Jiang, K. Middleton, H.-J. Yoon, C. Fouquet, and J. Carbon, Mol. Cell. Biol. 13:4884-4893, 1993). Cbf5p also binds microtubules in vitro and interacts genetical
Publikováno v:
The Journal of Cell Biology
Genetic and biochemical strategies have been used to identify Schizosaccharomyces pombe proteins with roles in centromere function. One protein, identified by both approaches, shows significant homology to the human centromere DNA-binding protein, CE
Autor:
Hye-Joo Yoon, John Carbon
Publikováno v:
Molecular and Cellular Biology. 15:4835-4842
CBF2/NDC10/CTF14 encodes the 110-kDa subunit of CBF3, a key component of the yeast centromere/kinetochore. Overexpression of yeast CDC34 specifically suppresses the temperature-sensitive growth phenotype of the ndc10-1 mutation. Mutations in CDC34, w
Autor:
Kim Middleton, John Carbon
Publikováno v:
Proceedings of the National Academy of Sciences. 91:7212-7216
We have used in vitro motility assays to investigate the mechanism of kinetochore function in the budding yeast Saccharomyces cerevisiae. Functional centromeric DNA plus a tripartite centromere binding protein complex, CBF3, was found to be necessary
Autor:
John Carbon, Michael Centola
Publikováno v:
Molecular and Cellular Biology. 14:1510-1519
The centromere locus from linkage group VII of Neurospora crassa has been cloned, characterized, and physically mapped. The centromeric DNA is contained within a 450-kb region that is recombination deficient, A+T-rich, and contains repetitive sequenc