Výsledky vyhledávání - "John Campana"

Phase 1/2a, open‐label, multicenter study ofRM‐1929 photoimmunotherapy in patients with locoregional, recurrent head and neck squamous cell carcinoma

Autor: Nilesh R. Vasan, Merrill A. Biel, Jennifer Johnson, Joseph Curry, Samith T. Kochuparambil, Darren McDonald, Mary J. Fidler, Frank E. Mott, Mohammad Razaq, Miguel Garcia-Guzman, Kosuke Ishida, Grace Mann, David Cognetti, Ann M. Gillenwater, John Campana, Kerstin M. Stenson, Patrick K. Ha

Publikováno v: Head & Neck. 43:3875-3887

Background Recurrent head and neck squamous cell carcinoma (rHNSCC) represents a significant global health burden with an unmet medical need. In this study we determined the safety and efficacy of RM-1929 photoimmunotherapy in patients with heavily p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171541f97e39a1c884705d83a599bbf0
https://doi.org/10.1002/hed.26885

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Targeted hypoglossal nerve stimulation for the treatment of obstructive sleep apnea: Six-month results

Autor: Ingo Fietze, Philippe Rombaux, Ofer Jacobowitz, Sreeya Yalamanchali, Michel Friedman, John Campana, Wolfgang Bergler, Gimbada Benny Mwenge, Joachim T. Maurer, Michelle S. Hwang

Publikováno v: The Laryngoscope. 126:2618-2623

Objectives/Hypothesis This feasibility study was designed to show the preliminary safety and efficacy of targeted hypoglossal neurostimulation (THN), and to identify baseline predictors of successful therapy. Study Design Open-label, prospective, mul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64be58ba9d3f744989d6a7c99dea726b
https://doi.org/10.1002/lary.25909

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Radiation-Induced Dedifferentiated Chondrosarcoma With Orbital Invasion

Autor: Antonio Augusto Velasco e Cruz, Vikram D. Durairaj, John Campana, Brett W. Davies, Sherif Said, Christina Rapp Prescott, Flávia A. Attié-Castro

Publikováno v: Ophthalmic Plastic & Reconstructive Surgery. 30:205-208

Purpose To report 2 interventional cases of dedifferentiated chondrosarcoma with orbital involvement after radiotherapy performed in childhood and to review the literature on chondrosarcoma in the orbit following radiation treatment. Methods Retrospe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fb473d430c5d44671186b939f0a93e
https://doi.org/10.1097/iop.0000000000000168

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Results of a phase 2a, multicenter, open-label, study of RM-1929 photoimmunotherapy (PIT) in patients with locoregional, recurrent head and neck squamous cell carcinoma (rHNSCC)

Autor: Jennifer Johnson, Mohammad Razaq, Darren McDonald, Kerstin M. Stenson, Merrill A. Biel, Nilesh R. Vasan, Samith T. Kochuparambil, Mary J. Fidler, Joseph Curry, Frank E. Mott, Ann M. Gillenwater, John Campana, David Cognetti

Publikováno v: Journal of Clinical Oncology. 37:6014-6014

6014 Background: Patients with rHNSCC who have failed standard of care have poor prognoses and limited therapeutic options. In this study, final results are reported of a phase 2a trial of photoimmunotherapy (PIT) with a targeted drug RM-1929, consis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36d45dcd67c2500584b86437f1e4c36d
https://doi.org/10.1200/jco.2019.37.15_suppl.6014

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RM-1929 photo-immunotherapy in patients with recurrent head and neck cancer: Results of a multicenter phase 2a open-label clinical trial

Autor: David Cognetti, Joseph Curry, Jennifer Johnson, Frank E. Mott, Mary J. Fidler, John Campana, Nilesh R. Vasan, Mohammad Razaq, Kerstin M. Stenson, Samith Thomas Kochuparambil, Ann M. Gillenwater, Darren McDonald

Publikováno v: Journal of Clinical Oncology. 36:6039-6039

6039Background: Patients with recurrent HNSCC (rHNSCC) have limited therapeutic options and poor prognosis. We report promising results of a Phase 2a trial of photoimmunotherapy (PIT) for the treat...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cb3dc34ede35ac15089bef86f864cc7
https://doi.org/10.1200/jco.2018.36.15_suppl.6039

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Phase I Trial of Gefitinib in Combination With Radiation or Chemoradiation for Patients With Locally Advanced Squamous Cell Head and Neck Cancer

Autor: Madeleine A. Kane, Anna E. Barón, Changhu Chen, Louis C. Harrison, David Raben, Kenneth S. Hu, John I. Song, John Campana, Sherif Said, S. Gail Eckhardt, Harry Quon, Adam Raben, Janet Dancey

Publikováno v: Journal of Clinical Oncology. 25:4880-4886

Purpose To establish the safety and toxicity profile of daily gefitinib with radiation alone or with concurrent chemoradiotherapy in previously untreated patients with locally advanced squamous cell head and neck cancer (LAHNC). Patients and Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54de0a52f07660f81cba6f5355deef2c
https://doi.org/10.1200/jco.2007.12.9650

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Targeted hypoglossal nerve stimulation for the treatment of obstructive sleep apnea: Six-month results

Autor: Michael, Friedman, Ofer, Jacobowitz, Michelle S, Hwang, Wolfgang, Bergler, Ingo, Fietze, Philippe, Rombaux, Gimbada B, Mwenge, Sreeya, Yalamanchali, John, Campana, Joachim T, Maurer

Publikováno v: The Laryngoscope. 126(11)

This feasibility study was designed to show the preliminary safety and efficacy of targeted hypoglossal neurostimulation (THN), and to identify baseline predictors of successful therapy.Open-label, prospective, multicenter, single-arm cohort study, c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69fdc743207553269f21bb0218dca145
https://pubmed.ncbi.nlm.nih.gov/27010361

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Detection of Occult Cervical Micrometastases in Patients With Head and Neck Squamous Cell Cancer

Autor: John Campana, Kenneth R. Shroyer, Bruce W. Jafek, Jose E. Barrera, Mark E. Miller, Sherif Said

Publikováno v: The Laryngoscope. 113:892-896

Objective The incidence of occult nodal metastases associated with head and neck squamous cell carcinoma (HNSCC) and the clinical significance of nodal micrometastases by cytokeratin immunohistochemical analysis are examined. Study Design In all, 101

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f796396b4bba42df48c39a71aae1d36
https://doi.org/10.1097/00005537-200305000-00022

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