Zobrazeno 1 - 10
of 879
pro vyhledávání: '"John CO"'
Autor:
Andrew Houston, Sophie Williams, William Ricketts, Charles Gutteridge, Chris Tackaberry, John Conibear
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background The digitisation of healthcare records has generated vast amounts of unstructured data, presenting opportunities for improvements in disease diagnosis when clinical coding falls short, such as in the recording of patient symptoms.
Externí odkaz:
https://doaj.org/article/fbcd42d6ad6b48029bc049e86d162234
Autor:
Peng V. Wu, Matt Fish, Florette K. Hazard, Chunfang Zhu, Sujay Vennam, Hannah Walton, Dhananjay Wagh, John Coller, Joanna Przybyl, Maurizio Morri, Norma Neff, Robert B. West, Roel Nusse
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Cancers evolve not only through the acquisition and clonal transmission of somatic mutations but also by epigenetic mechanisms that modify cell phenotype. Here, we use histology-guided and spatial transcriptomics to characterize hepatoblasto
Externí odkaz:
https://doaj.org/article/2d94ec01e9d046b7b6d307f07deb9f1b
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Misinformation about climate change is a complex societal issue that requires holistic, interdisciplinary solutions at the intersection between technology and psychology. One proposed solution is a “technocognitive” approach, involving t
Externí odkaz:
https://doaj.org/article/d6a61ec8dd0a46bb8ee768aea575344f
Autor:
John Corbyn Cravero, Laith Wahab, Dirk T. Wilson, Ali Alani, Arthur Bredeweg, Roberto Aguirre
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 1294-1300 (2024)
Introduction: Primary pulmonary artery sarcoma is a rare malignancy with a poor prognosis, undefined treatment guidelines, and is often mistaken for a pulmonary embolism (PE) based on similar clinical presentation and radiographic findings. Case Pres
Externí odkaz:
https://doaj.org/article/fb186d6e049e4459882bc7e55ce9a05a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In estimating radiation-related risk of cancer and other diseases based on the RERF Life Span Study (LSS), joint analyses can be performed where multiple health outcome endpoints are combined in the same model, allowing some parameters to be
Externí odkaz:
https://doaj.org/article/b55ff2033c0e49d4a70a14d864dbca26
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
Autor:
Samuel Abassah-Oppong, Matteo Zoia, Brandon J. Mannion, Raquel Rouco, Virginie Tissières, Cailyn H. Spurrell, Virginia Roland, Fabrice Darbellay, Anja Itum, Julie Gamart, Tabitha A. Festa-Daroux, Carly S. Sullivan, Michael Kosicki, Eddie Rodríguez-Carballo, Yoko Fukuda-Yuzawa, Riana D. Hunter, Catherine S. Novak, Ingrid Plajzer-Frick, Stella Tran, Jennifer A. Akiyama, Diane E. Dickel, Javier Lopez-Rios, Iros Barozzi, Guillaume Andrey, Axel Visel, Len A. Pennacchio, John Cobb, Marco Osterwalder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Approximately a quarter of the human genome consists of gene deserts, large regions devoid of genes often located adjacent to developmental genes and thought to contribute to their regulation. However, defining the regulatory functions embed
Externí odkaz:
https://doaj.org/article/ea97ba56f1764b518e534e1063bf2e68
Publikováno v:
Scholars International Journal of Obstetrics and Gynecology. 5:101-103
Chancroid is a sexually transmitted disease (STD) caused by the Gram-negative bacterium Haemophilus ducreyi and is characterised by necrotising genito-perineal ulcers which may be accompanied by inguinal lymphadenitis or bubo formation with possible
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract ρ-type γ-aminobutyric acid-A (GABAA) receptors are widely distributed in the retina and brain, and are potential drug targets for the treatment of visual, sleep and cognitive disorders. Endogenous neuroactive steroids including β-estradio
Externí odkaz:
https://doaj.org/article/670fbe13ae4d4d80830997f0f83876d5
Autor:
Brian S. White, Aurélien de Reyniès, Aaron M. Newman, Joshua J. Waterfall, Andrew Lamb, Florent Petitprez, Yating Lin, Rongshan Yu, Martin E. Guerrero-Gimenez, Sergii Domanskyi, Gianni Monaco, Verena Chung, Jineta Banerjee, Daniel Derrick, Alberto Valdeolivas, Haojun Li, Xu Xiao, Shun Wang, Frank Zheng, Wenxian Yang, Carlos A. Catania, Benjamin J. Lang, Thomas J. Bertus, Carlo Piermarocchi, Francesca P. Caruso, Michele Ceccarelli, Thomas Yu, Xindi Guo, Julie Bletz, John Coller, Holden Maecker, Caroline Duault, Vida Shokoohi, Shailja Patel, Joanna E. Liliental, Stockard Simon, Tumor Deconvolution DREAM Challenge consortium, Julio Saez-Rodriguez, Laura M. Heiser, Justin Guinney, Andrew J. Gentles
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract We evaluate deconvolution methods, which infer levels of immune infiltration from bulk expression of tumor samples, through a community-wide DREAM Challenge. We assess six published and 22 community-contributed methods using in vitro and in
Externí odkaz:
https://doaj.org/article/fbdd2912b0694dcb86f190414734e1ac
Publikováno v:
Remote Sensing in Ecology and Conservation, Vol 10, Iss 4, Pp 551-562 (2024)
Abstract Peatlands, constituting over half of terrestrial wetland ecosystems across the globe, hold critical ecological significance and are large stores of carbon (C). Irish oceanic raised bogs are a rare peatland ecosystem offering numerous ecosyst
Externí odkaz:
https://doaj.org/article/b0abb4c27f7c4a019b0b755c4290db90