Zobrazeno 1 - 5
of 5
pro vyhledávání: '"John C.K. Lai"'
Autor:
Yeshitila Gebremichael, Evren Atillasoy, Brett A. Howell, F. Jay Murray, Kyunghee Yang, Hartmut Jaeschke, Edwin Kuffner, John C.K. Lai, Gary Eichenbaum, Cathy K. Gelotte, Daniele Wikoff, David Jacobson-Kram
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 118
In 2019, the California Office of Environmental Health Hazard Assessment (OEHHA) initiated a review of the carcinogenic hazard potential of acetaminophen. The objective of the analysis herein was to inform this review by assessing whether variability
Autor:
Edwin Kuffner, Samuel M. Cohen, Milind Deore, Andrew D. Monnot, Evren Atillasoy, Gary Eichenbaum, Cathy K. Gelotte, Anne Hermanowski-Vosatka, Suren B. Bandara, Michael Kovochich, Jerry F. Hardisty, Brett A. Howell, Suresh Kumar Pitchaiyan, F. Jay Murray, Kyunghee Yang, John C.K. Lai, Yeshitila Gebremichael, Kenneth M. Unice, David Jacobson-Kram
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 118
In 2019 the California Office of Environmental Health Hazard Assessment (OEHHA) initiated a review of the carcinogenic hazard potential of acetaminophen, including an assessment of the long-term rodent carcinogenicity and tumor initiation/promotion s
Autor:
John C.K. Lai, Caroline Cheung, Honglin Luo, Jingchun Zhang, Hon S. Leong, Bobby Yanagawa, Agripina Suarez, Bruce M. McManus, Dinesh Samarasekera
Publikováno v:
Cardiovascular Pathology. 15:63-74
Background: Coxsackievirus B3 (CVB3) is the major causative agent of myocarditis in humans. In the mouse model, the inflammatory phase of myocarditis results in extensive damage to the heart and triggers profound extracellular matrix (ECM) remodeling
Autor:
Donald Wong, Alexandra Kerjner, Sylvia Loo, John C.K. Lai, Mohammed H. Moghadasian, David C. Walker, Bruce M. McManus, Dean English, Erin M. Tranfield, Janet E. Wilson, Paul C. McDonald, Jennifer Dyck
Publikováno v:
The Journal of Heart and Lung Transplantation. 22:993-1004
Background: Events that occur early after transplantation, particularly immune recognition of allo-endothelium, initiate transplant vascular disease (TVD). Previous work suggests an important compromise of endothelial integrity as the allo-immune mil
Autor:
Jonathan C. Choy, Bobby Yanagawa, Bruce M. McManus, John C.K. Lai, Thomas J. Podor, David J. Granville, David C. Walker
Publikováno v:
Cardiovascular Toxicology. 3:269-282
Atheromatous diseases are lipid and cell-rich vascular disorders that include coronary artery disease (CAD), transplant vascular disease (TVD), and restenosis. Considering the inflammatory nature of these diseases, cytotoxic immune mechanisms such as