Spectrin Genes

Autor: John C. Winkelmann, Thomas L. Leto, Bernard G. Forget

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a2d8029773e1bb578efb99c53a52bc
https://doi.org/10.4324/9781003066118-5

Paclitaxel-induced diffuse cutaneous sclerosis: a case with associated esophageal dysmotility, Raynaud's phenomenon, and myositis

Autor: Richard R. Winkelmann, W. Leroy Griffing, James A. Yiannias, John C. Winkelmann, Yolanda Farhey, Shannon C. Trotter, Lisa M. Martorano, David J. DiCaudo

Publikováno v: International Journal of Dermatology. 55:97-100

A 64-year-old woman with a history of alopecia and hypothyroidism was diagnosed with ovarian cancer. Following hysterectomy and bilateral oophorectomy with omentectomy, surgical pathology revealed poorly differentiated serous adenocarcinoma with pelv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b209ac55f526b8bbe84c5555d0ba54c6
https://doi.org/10.1111/ijd.12437

Fox-2 Splicing Factor Binds to a Conserved Intron Motif to Promote Inclusion of Protein 4.1R Alternative Exon 16

Autor: Christina Schluepen, Weiguo Chen, Annie J. Lo, Victor C. Hou, John C. Winkelmann, Joel Anne Chasis, Sarah A. Short, Sherry L. Gee, John G. Conboy, Julie L. Ponthier, Robert A. Lersch

Publikováno v: Ponthier, Julie L.; Schluepen, Christina; Chen, Weiguo; Lersch, Robert A.; Gee, Sherry L.; Hou, Victor C.; et al.(2006). Fox-2 Splicing Factor Binds to a Conserved Intron Motif to Promote Inclusion of Protein 4.1R Alternative Exon 16. Lawrence Berkeley National Laboratory. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/8kw9q4sv

Activation of protein 4.1R exon 16 (E16) inclusion during erythropoiesis represents a physiologically important splicing switch that increases 4.1R affinity for spectrin and actin. Previous studies showed that negative regulation of E16 splicing is m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bd0dab149e69be8fab90e620f49ebc
https://doi.org/10.1074/jbc.m511556200

Amino-acid substitution in α-spectrin commonly coinherited with nondominant hereditary spherocytosis

Autor: John C. Winkelmann, David W. Speicher, Bernard G. Forget, Patricia B. Jenkins, Sally L. Marchesi, William T. Tse, Patrick G. Gallagher, Lori Benoit, Yong-Ping Wang, Peter Agre

Publikováno v: American Journal of Hematology. 54:233-241

Nondominant hereditary spherocytosis (ndHS) is a disorder characterized in some patients by severe hemolytic anemia and marked deficiency of erythrocyte spectrin. This report describes the identification of a variant spectrin chain, alpha-spectrin Bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9e0ea3d13adf60649635c189d46a287
https://doi.org/10.1002/(sici)1096-8652(199703)54:3<233::aid-ajh10>3.0.co

Erythroid-specific processing of human beta spectrin I pre-mRNA

Autor: Sanford B. Krantz, John C. Winkelmann, Amittha Wickrema, Zhi-Liang Chu

Publikováno v: Blood. 84:1992-1999

Erythroid cells express a unique form of beta spectrin I as a result of tissue-specific alternative pre-mRNA processing. Nonerythroid cells that express the beta spectrin I gene include four additional exons at the 3′ end of the mature transcript,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0646f52e7f2bbc37389157414d0cd09
https://doi.org/10.1182/blood.v84.6.1992.1992