Zobrazeno 1 - 10
of 126
pro vyhledávání: '"John C. Voss"'
Autor:
Silvia Hilt, Ruiwu Liu, Izumi Maezawa, Tatu Rojalin, Hnin H. Aung, Madhu Budamagunta, Ryan Slez, Qizhi Gong, Randy P. Carney, John C. Voss
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Several neurodegenerative diseases are driven by misfolded proteins that assemble into soluble aggregates. These “toxic oligomers” have been associated with a plethora of cellular dysfunction and dysregulation, however the structural features und
Externí odkaz:
https://doaj.org/article/575a1b403849475ca12a31cf7a3d0cda
Autor:
Sarah Waldie, Federica Sebastiani, Martine Moulin, Rita Del Giudice, Nicolò Paracini, Felix Roosen-Runge, Yuri Gerelli, Sylvain Prevost, John C. Voss, Tamim A. Darwish, Nageshwar Yepuri, Harald Pichler, Selma Maric, V. Trevor Forsyth, Michael Haertlein, Marité Cárdenas
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Apolipoprotein E (ApoE), an important mediator of lipid transportation in plasma and the nervous system, plays a large role in diseases such as atherosclerosis and Alzheimer's. The major allele variants ApoE3 and ApoE4 differ only by one amino acid.
Externí odkaz:
https://doaj.org/article/9633a3e54bf542e08dd5a894dd1ccae2
Autor:
Hnin Hnin Aung, Robin Altman, Tun Nyunt, Jeffrey Kim, Saivageethi Nuthikattu, Madhu Budamagunta, John C. Voss, Dennis Wilson, John C. Rutledge, Amparo C. Villablanca
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 6, Pp 955-968 (2016)
Dysfunction of the cerebrovasculature plays an important role in vascular cognitive impairment (VCI). Lipotoxic injury of the systemic endothelium in response to hydrolyzed triglyceride-rich lipoproteins (TGRLs; TGRL lipolysis products) or a high-fat
Externí odkaz:
https://doaj.org/article/5420b5caf8744e748dc6bfad68479f33
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 9, Pp 2731-2738 (2010)
The ability to exogenously present cell-surface receptors in high-affinity conformations in a synthetic system offers an opportunity to provide host cells with protection from pathogenic toxins. This strategy requires improvement of the synthetic rec
Externí odkaz:
https://doaj.org/article/5241dd8b8f4a41948633cc5afccf19e3
Autor:
Silvia Hilt, Robin Altman, Tamás Kálai, Izumi Maezawa, Qizhi Gong, Sebastian Wachsmann-Hogiu, Lee-Way Jin, John C. Voss
Publikováno v:
Molecules, Vol 23, Iss 8, p 2010 (2018)
There is growing recognition regarding the role of intracellular amyloid beta (Aβ) in the Alzheimer’s disease process, which has been linked with aberrant signaling and the disruption of protein degradation mechanisms. Most notably, intraneuronal
Externí odkaz:
https://doaj.org/article/f5cbbe1e1410439fa77872df3bbd254c
Autor:
Sarada D. Tetali, Madhu S. Budamagunta, Catalina Simion, Laura J. den Hartigh, Tamás Kálai, Kálmán Hideg, Danny M. Hatters, Karl H. Weisgraber, John C. Voss, John C. Rutledge
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1273-1283 (2010)
Our previous work indicated that apolipoprotein (apo) E4 assumes a more expanded conformation in the postprandial period. The postprandial state is characterized by increased VLDL lipolysis. In this article, we tested the hypothesis that VLDL lipolys
Externí odkaz:
https://doaj.org/article/a192d613c55941ec927e65679a6b4d18
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 7, Pp 1358-1365 (2006)
Increased triglyceride-rich lipoproteins (TGRLs) in the postprandial state are associated with atherosclerosis. We investigated whether the postprandial state induced structural changes at the apolipoprotein E4 (apoE4) C terminus, its principal lipid
Externí odkaz:
https://doaj.org/article/70789982f7fb4da6bee40a193f09fb9a
Autor:
Meruyert Imanbekova, Tatu Rojalin, Silvia Hilt, Randy P. Carney, John C. Voss, Ayse Mine Saridag, Mehmet Kahraman, Humeyra Caglayan
Publikováno v:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX.
Publikováno v:
Journal of Clinical Monitoring and Computing. 35:1485-1489
Quantification of plasma propofol (2,6-diisopropylphenol) in the context of clinical anaesthesia is challenging because of the need for offline blood sample processing using specialised laboratory equipment and techniques. In this study we sought to
Autor:
Meruyert Imanbekova, Juanjuan Liu, Tatu Rojalin, Sorina Suarasan, Sebastian Wachsmann-Hogiu, Silvia Hilt, John C. Voss
Publikováno v:
Journal of Materials Chemistry B. 8:8845-8852
Using a regular CMOS sensor as a template, we are able to fabricate a simple but highly effective superhydrophobic SERS substrate. Specifically, we decorated the microlens layer of the sensor with 7 μm polystyrene beads to obtain a PDMS patterned re