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Autor: John C. Sok, Clark A. Rosen, Libby J. Smith, Alison L. Sukits, Mark S. Redfern, Melissa M. Statham

Publikováno v: The Laryngoscope. 120:297-305

Objectives/Hypothesis: To apply ergonomic principles in analysis of three different operative positions used in laryngeal microsurgery. Study Design: Prospective case-control study. Methods: Laryngologists were studied in three different microlarynge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1938fcc2957e84d2a9b3ccad870d5f59
https://doi.org/10.1002/lary.20686

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Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

Autor: Jennifer R. Grandis, Francesca M. Coppelli, Sufi M. Thomas, John C. Sok, Darell D. Bigner, Miriam N. Lango, Carol J. Wikstrand, William E. Gooding, Sichuan Xi, Frank B. Furnari, Maria L. Freilino, Jennifer L. Hunt, Michael W. Graner

Publikováno v: Clinical Cancer Research. 12:5064-5073

Purpose: Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinoma (HNSCC) where expression levels correlate with decreased survival. Therapies that block EGFR have shown limited efficacy in clinical trials and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f945352f385d771b8ffa2e5534ba046d
https://doi.org/10.1158/1078-0432.ccr-06-0913

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Differential diagnosis of eosinophilic chronic rhinosinusitis

Autor: Berrylin J. Ferguson, John C. Sok

Publikováno v: Current Allergy and Asthma Reports. 6:203-214

Eosinophilic chronic rhinosinusitis (ECRS) encompasses a wide variety of etiologies. To date, a unifying pathophysiologic mechanism remains elusive. Eosinophilia is frequently, but not exclusively, caused by immunoglobulin (Ig)E-mediated hypersensiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c3d3381e1731666717242336b9f156
https://doi.org/10.1007/s11882-006-0036-1

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Signaling through the epidermal growth factor receptor during the development of malignancy

Autor: John C. Sok, Jennifer R. Grandis

Publikováno v: Pharmacology & Therapeutics. 102:37-46

The epidermal growth factor receptor (EGFR) is overexpressed and/or constitutively activated in a variety of human malignancies. Detection of increased expression levels of EGFR in cancer and the association between overexpression and decreased patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c6fb52fba58af2954d3e3c4cba3701
https://doi.org/10.1016/j.pharmthera.2004.01.002

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Collagen type XI α1 facilitates head and neck squamous cell cancer growth and invasion

Autor: John C. Sok, Sarah Contrucci, Brian K. Trevelline, J A Lee, Sufi M. Thomas, Sumana Dasari, Radhika Joshi, Ann Marie Egloff, Jennifer R. Grandis, N Kumari, Sonali Joyce

Publikováno v: Grandis, Jennifer; Sok, JC; Lee, JA; Dasari, S; Joyce, S; Contrucci, SC; et al.(2013). Collagen type XI α1 facilitates head and neck squamous cell cancer growth and invasion. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0s69b4d5
British Journal of Cancer

Background: Although it is well established that the extracellular matrix affects tumour progression, not much is known about the various components and their effect on head and neck squamous cell carcinoma (HNSCC) progression. Levels of collagen typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e5178b5ff989fdfb38e643b2a6fcc3
http://www.escholarship.org/uc/item/0s69b4d5

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Genetic screening for oral human papillomavirus infections and cancers of the head and neck

Autor: Jennifer R. Grandis, John C. Sok

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 14(21)

Detection and type-specific identification of human papillomavirus infection obtained from oral rinse sampling may have future clinical utility for identifying individuals at higher risk for a subset of oropharyngeal cancers.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60568f6e523a671185a8a15b74c604e
https://pubmed.ncbi.nlm.nih.gov/18981014

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