Zobrazeno 1 - 10
of 26
pro vyhledávání: '"John C. Sisson"'
Autor:
Greg T. Cantin, Ophelia Papoulas, Young Hee Ryu, Cristian I. Ruse, Kathryn F. Monzo, John C. Sisson, John R. Yates
Publikováno v:
Development. 137:4201-4209
The molecular mechanisms driving the conserved metazoan developmental shift referred to as the mid-blastula transition (MBT) remain mysterious. Typically, cleavage divisions give way to longer asynchronous cell cycles with the acquisition of a gap ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370c4eefe703288fd76e11405119f45e
https://doi.org/10.1242/dev.055046
https://doi.org/10.1242/dev.055046
Publikováno v:
Developmental Biology. 340:408-418
Fragile X mental retardation protein (FMRP) is an RNA-binding protein that is required for the translational regulation of specific target mRNAs. Loss of FMRP causes Fragile X syndrome (FXS), the most common form of inherited mental retardation in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ca178ceb93275aa90d7b2b75e88a68
https://doi.org/10.1016/j.ydbio.2010.01.028
https://doi.org/10.1016/j.ydbio.2010.01.028
Publikováno v:
Microfluidics and Nanofluidics. 6:299-313
A combination of genetic regulation and microenvironmental perturbation might prove especially useful for identifying the fundamental mechanisms responsible for development biology and critical bio-chemical networks. This could transform our understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec26ae9f430a1ef2b421564f49fd002c
https://doi.org/10.1007/s10404-009-0405-x
https://doi.org/10.1007/s10404-009-0405-x
Publikováno v:
Proceedings of the National Academy of Sciences. 103:18160-18165
During the cleavage stage of animal embryogenesis, cell numbers increase dramatically without growth, and a shift from maternal to zygotic genetic control occurs called the midblastula transition. Although these processes are fundamental to animal de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c918f41a84e8e7145644471209d41492
https://doi.org/10.1073/pnas.0606508103
https://doi.org/10.1073/pnas.0606508103
Autor:
Gerardo Jiménez, William J. Sullivan, Robin Abu-Shumays, Thomas Kidd, John C. Sisson, Sheena M. Pinchin, Alisa L. Katzen, David Ish-Horowicz
Publikováno v:
Genetics. 170:697-708
We describe the maternal-effect and zygotic phenotypes of null mutations in the Drosophila gene for the ε-subunit of mitochondrial ATP synthase, stunted (sun). Loss of zygotic sun expression leads to a dramatic delay in the growth rate of first inst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e30d6539ab47cb523b7c2ab215abd7
https://doi.org/10.1534/genetics.104.037648
https://doi.org/10.1534/genetics.104.037648
Publikováno v:
Nature Cell Biology. 7:612-618
Drosophila melanogaster cellularization is a dramatic form of cytokinesis in which a membrane furrow simultaneously encapsulates thousands of cortical nuclei of the syncytial embryo to generate a polarized cell layer. Formation of this cleavage furro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51f45a7cedd91bb41ed48d03a5b7738
https://doi.org/10.1038/ncb1264
https://doi.org/10.1038/ncb1264
Autor:
Kevin Moses, Peng Jin, Juergen A. Knoblich, Joerg Betschinger, Mika Nakamoto, Thomas C. Dockendorff, Stephen T. Warren, Thomas A. Jongens, Yue Feng, John C. Sisson, Yan Wang, Daniela C. Zarnescu
Publikováno v:
Developmental Cell. 8:43-52
Fragile X syndrome, the most common form of inherited mental retardation, is caused by loss of function for the Fragile X Mental Retardation 1 gene (FMR1). FMR1 protein (FMRP) has specific mRNA targets and is thought to be involved in their transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777c772090f0f97799ffa5a91320746e
https://doi.org/10.1016/j.devcel.2004.10.020
https://doi.org/10.1016/j.devcel.2004.10.020
Publikováno v:
Molecular Biology of the Cell. 15:838-850
The early Drosophila embryo undergoes two distinct membrane invagination events believed to be mechanistically related to cytokinesis: metaphase furrow formation and cellularization. Both involve actin cytoskeleton rearrangements, and both have myosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57be48ced1157b58b473bf07fb80e4bb
https://doi.org/10.1091/mbc.e03-06-0440
https://doi.org/10.1091/mbc.e03-06-0440
Lava Lamp, a Novel Peripheral Golgi Protein, Is Required for Drosophila melanogaster Cellularization
Publikováno v:
Journal of Cell Biology. 151:905-918
Drosophila cellularization and animal cell cytokinesis rely on the coordinated functions of the microfilament and microtubule cytoskeletal systems. To identify new proteins involved in cellularization and cytokinesis, we have conducted a biochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f3cc6f7ff4339b1d0d62029ee3cf0d
https://doi.org/10.1083/jcb.151.4.905
https://doi.org/10.1083/jcb.151.4.905
Publikováno v:
Cell. 90:235-245
The Hedgehog (HH) signaling proteins control cell fates and patterning during animal development. In Drosophila, HH protein induces the transcription of target genes encoding secondary signals such as DPP and WG proteins by opposing a repressor syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e88f2d9d25212456bea1855ffc1f9f
https://doi.org/10.1016/s0092-8674(00)80332-3
https://doi.org/10.1016/s0092-8674(00)80332-3