Zobrazeno 1 - 10
of 17
pro vyhledávání: '"John C. O'Neill"'
Publikováno v:
Journal of Clinical Psychology. 79:871-885
Nonsuicidal self-injury (NSSI) frequently functions to regulate shame-based emotions and cognitions in the context of interpersonal stress. The present study sought to examine how sleep quality (SQ) may influence this process in a laboratory setting.
Autor:
Zhihua Sui, Cuifen Hou, Dave F. McComsey, Evan Opas, Dana L. Johnson, Sandra McKenney, John C. O’Neill, Chaozhong Cai
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:1239-1242
SAR study of 5-aminooctahydrocyclopentapyrrole-3a-carboxamide scaffold led to identification of several CCR2 antagonists with potent activity in both binding and functional assays. Their cardiovascular safety and pharmacokinetic properties were also
Autor:
Brodie Miles, Julio A. Carrion, John C. O'Neill, Aaron Rawlings, Elizabeth Scisci, J. Kobi Stern, Ibrahim Zakhary, Christopher W. Cutler, Cristiano Susin, Ahmed El-Awady
Publikováno v:
Infection and Immunity. 82:101-111
Several intracellular pathogens, including a key etiological agent of chronic periodontitis, Porphyromonas gingivalis , infect blood myeloid dendritic cells (mDCs). This infection results in pathogen dissemination to distant inflammatory sites (i.e.,
Publikováno v:
Sport, Business and Management: An International Journal. 3:78-96
PurposeThe purpose of this research is to investigate the extent to which actual and ideal self‐congruities (image) are associated with health club patronage, a conspicuous consumption situation. Previous studies which have examined the applicabili
Autor:
Cynthia Milligan, Hossein Askari, Marta C. Abad, Frank Lewandowski, Barry A. Springer, John C. O’Neill, John C. Spurlino, Dionisios Rentzeperis, Alexandra L. Klinger
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 108:44-54
We screened the ligand-binding domain of estrogen-related receptor (ERR) gamma in ThermoFluor, in an effort to develop chemical tools and decipher the biology of this orphan nuclear receptor. Several ligands were found to stabilize thermodynamically
Autor:
John C. O’Neill, James F. Booker
Publikováno v:
Journal of Water Resources Planning and Management. 132:520-523
The effect of reservoir losses on the economically optimal use of reservoir storage capacity is explored theoretically and numerically. We demonstrate that reservoir seepage and evaporation losses lead to a trade-off between the reliability and mean
Publikováno v:
Journal of Molecular Biology. 326:569-583
The propensity for peptide bonds to adopt the trans configuration in native and unfolded proteins, and the relatively slow rates of cis – trans isomerization reactions, imply that the formation of cis peptide bonds in native conformations are likel
Autor:
Cuifen Hou, John C. O’Neill, Zhihua Sui, Fu-An Kang, Michael P. Winters, Thomas Kirchner, David F. McComsey, Dana L. Johnson, Ping Wang, Christopher A. Teleha
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(9)
The discovery of a novel series of cyclopenta[b]furans as CCR2 inhibitors is discussed. This series has excellent CCR2 potency and PK characteristics, and good cardiovascular safety.
Autor:
John C. O'neill, Edward C. Turner
Publikováno v:
International Journal of Algebra and Computation. 10:751-756
We characterize test elements in the commutator subgroup of a direct product of certain groups in terms of test elements of the factors. This provides explicit examples of test elements in direct products whose factors are free groups or surface grou
Autor:
John C O’Neill, C. Robert Matthews
Publikováno v:
Journal of Molecular Biology. 295:737-744
Mutational analysis was performed to probe the development of hydrophobic clusters during the early events in the folding of dihydrofolate reductase. Replacements were made in several hydrophobic subdomains to examine the roles of hydrophobicity and