Zobrazeno 1 - 10
of 14
pro vyhledávání: '"John C. McMichael"'
Polymorphism of the major surface epitope of the CopB outer membrane protein ofMoraxella catarrhalis
Autor:
Steven M. Baker, Dai Fang Liu, Maria Mastri, John C. McMichael, Xiaoling Xie, Deborah A. Dilts, Christopher Colocillo, Maria Fortuna-Nevin, Leah D. Fletcher
Publikováno v:
FEMS Immunology & Medical Microbiology. 47:343-350
The CopB outer membrane protein has been considered a vaccine candidate for the prevention of infections due to Moraxella catarrhalis. Monoclonal antibody 10F3 recognizes whole cells of about 70% of clinical isolates, suggesting that this epitope is
Autor:
Gary W. Zlotnick, John C. McMichael, Kathryn Mason, Duzhang Zhu, Catherine A. Scheuer, Bruce A. Green
Publikováno v:
Vaccine. 22:3449-3456
Nontypeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis are common causative agents of human mucosal infections. To formulate a mucosal vaccine against these pathogens, recombinant lipidated P4 (rLP4) and P6 (rLP6) proteins of NTHi and ub
Publikováno v:
International Congress Series. 1257:121-125
Nontypeable Haemophilus influenzae and Moraxella catarrhalis colonize and infect human mucosal membranes. To improve protection against these pathogens, we have explored the capacity of vaccines to elicit an immune response when intranasally delivere
Autor:
John C. McMichael
Publikováno v:
Vaccine. 19:S101-S107
Vaccine development for Moraxella catarrhalis is in the antigen identification stage. M. catarrhalis does not appear to synthesize secreted antigens such as exotoxins, nor does it appear to possess a carbohydrate capsule. Modified forms of these anti
Autor:
John C McMichael
Publikováno v:
Microbes and Infection. 2:561-568
Moraxella catarrhalis is a major cause of otitis media and respiratory disease. Vaccine development is at the antigen identification stage. This review examines the more promising antigens, including the 200K protein, the hemagglutinins, the lactofer
Publikováno v:
Infection and Immunity. 67:1310-1316
The UspA1 and UspA2 proteins from Moraxella catarrhalis share antigenic epitopes and are promising vaccine candidates. In this study, the levels and bactericidal activities of antibodies in sera from healthy adults and children toward UspA1 and UspA2
Autor:
John C. McMichael
Publikováno v:
Journal of General Microbiology. 138:2687-2695
SUMMARY: Moraxella bovis was found to colonize the interface between agar and the polystyrene Petri dish, producing circular colonies when the inoculum was stabbed at a single point. The bacteria occurred in a thin layer of nearly uniform thickness,
The outer membrane protein CD of Moraxella catarrhalis is considered to be a potential vaccine antigen against Moraxella infection. We purified the native CD from isolate O35E, administered it to mice, and detected considerable titers of anti-CD anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10d38e529394a9c93b4162f61af34cf
https://europepmc.org/articles/PMC1932855/
https://europepmc.org/articles/PMC1932855/
Publikováno v:
Infection and immunity. 69(3)
A monoclonal antibody (MAb), designated MAb 8E7 (immunoglobulin G3), specific for Moraxella catarrhalis lipooligosaccharide (LOS) was evaluated for its functional activity in vitro and in a mouse model of colonization. Enzyme-linked immunosorbent ass
Autor:
Vicki Barniak, Dexiang Chen, John C. McMichael, Eric Bortell, Amy W. Masi, Karl R. VanDerMeid, Deb N. Chakravarti, Jeffrey D. Caplan
Publikováno v:
Vaccine. 18(1-2)
An outer membrane protein from Moraxella catarrhalis with a mass of 74-kDa was isolated and evaluated as a vaccine candidate. The 74-kDa protein binds transferrin, and appears to be related to the other proteins from the organism that are reported to