Zobrazeno 1 - 10
of 25
pro vyhledávání: '"John C. Maule"'
Autor:
David F. Daggett, Georgina E Hollway, Peter D. Currie, Phillipe Gautier, John C. Maule, Christine Neyt, Fernando Cortes, Robert J. Bryson-Richardson, David G Keenan
Publikováno v:
Developmental Cell. 5:865-876
Slow-twitch muscle fibers of the zebrafish myotome undergo a unique set of morphogenetic cell movements. During embryogenesis, slow-twitch muscle derives from the adaxial cells, a layer of paraxial mesoderm that differentiates medially within the myo
Autor:
Douglas Blackwood, Helen S. Torrance, David R. Bentley, Judith A. Fantes, John C. Maule, Mark T. Ross, Diane Lawson, Kathryn L. Evans, Stephanie Le Hellard, M. Pat Malloy, Sean Humphray, S. W. Morris, Claire Whitton, Colin A. Semple, David J. Porteous, Walter J. Muir
Publikováno v:
Genomics. 71:315-323
Bipolar affective disorder (BPAD) is a complex disease with a significant genetic component and a population lifetime risk of 1%. Our previous work identified a region of human chromosome 4p that showed significant linkage to BPAD in a large pedigree
Autor:
Sheila Christie, John C. Maule, Yoshiro Shibasaki, Susan Anderson, Rebecca S. Devon, J. Brown, Anthony J. Brookes, David J. Porteous, Kathryn L. Evans
Publikováno v:
American Journal of Medical Genetics. 74:82-90
A 1.3Mb chromosome 11-specific yeast artificial chromosome (YAC) that spans a t(1;11) translocation breakpoint associated with major psychosis has been used to enrich cDNAs that are encoded within it and expressed in the human foetal brain. Database
Autor:
Anthony J. Brookes, Diane Lawson, E M Slorach, John C. Maule, David J. Porteous, J.E.V. Watson
Publikováno v:
Genome Research. 5:444-452
We describe a strategy to introduce preferentially the dominant selectable marker neoR into the human chromosome within a monochromosome hybrid cell line. Integration of a construct containing the marker is mediated by human-specific repeat elements
Autor:
Kathryn L. Evans, John Brown, Yoshiro Shibasaki, Rebecca S. Devon, Lin He, Benoit Arveiler, Sheila Christie, John C. Maule, David Baillie, Euan M. Slorach, Susan M. Anderson, John R. Gosden, Joelle Petit, Andreas Weith, Christine M. Gosden, Douglas H.R. Blackwood, David M. St. Clair, Walter J. Muir, Anthony J. Brookes, David J. Porteous
Publikováno v:
Genomics. 28:420-428
Forty-nine clones derived by microdissection of a schizophrenia-associated t(1;11)(q42.1;q14.3) breakpoint region have been assigned by somatic cell hybrid mapping to seven discrete intervals on the long arm of human chromosome 11. Eleven of the clon
Autor:
Daryll K. Green, John C. Maule
Publikováno v:
Analytical Biochemistry. 191:390-395
The design and construction of a transistor-driven hexagonal contour-clamped homogeneous electric field (CHEF) apparatus is discussed in detail. The addition of computer control of pulsed-field timings and experiment duration gives rise to an efficie
Publikováno v:
Yeyati, P L, Bancewicz, R M, Maule, J & van Heyningen, V 2007, ' Hsp90 selectively modulates phenotype in vertebrate development ', PLoS Genetics, vol. 3, no. 3, pp. e43 . https://doi.org/10.1371/journal.pgen.0030043
PLoS Genetics, Vol 3, Iss 3, p e43 (2007)
PLoS Genetics
PLoS Genetics, Vol 3, Iss 3, p e43 (2007)
PLoS Genetics
Compromised heat shock protein 90 (Hsp90) function reveals cryptic phenotypes in flies and plants. These observations were interpreted to suggest that this molecular stress-response chaperone has a capacity to buffer underlying genetic variation. Con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db7c50f29ec6cb0ca841ae0569669db
https://www.pure.ed.ac.uk/ws/files/7958337/Hsp90_selectively_modulates_phenotype_in_vertebrate_development.pdf
https://www.pure.ed.ac.uk/ws/files/7958337/Hsp90_selectively_modulates_phenotype_in_vertebrate_development.pdf
Publikováno v:
Technical Tips Online. 3:66-68
Autor:
David G Keenan, Danielle Fischer, Carol Wicking, Claudia Lohs, Philippe Gautier, Timothy Evans, John C. Maule, Peter D. Currie, Georgina E Hollway
Publikováno v:
Developmental biology. 294(1)
The Hedgehog family of secreted morphogens specifies the fate of a large number of different cell types within invertebrate and vertebrate embryos, including the muscle cell precursors of the embryonic myotome of zebrafish. Formation of Hedgehog-sens