Zobrazeno 1 - 10 of 16 pro vyhledávání: '"John C. Lewin"'
1
FDA’s dilemma with the aducanumab approval: public pressure and hope, surrogate markers and efficacy, and possible next steps
Autor: John G Rizk, John C Lewin
Publikováno v: BMJ Evidence-Based Medicine. 28:78-82
Accelerating Food and Drug Administration (FDA) product approval to market based on surrogate markers in the absence of proven efficacy creates a risk of adverse outcomes for affected patients, even in response to a life-threatening condition, such a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656ddd4b998457d65138744938ae0ccc
https://doi.org/10.1136/bmjebm-2022-111914
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2
Clinical Characteristics and Pharmacological Management of COVID-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia With Cerebral Venous Sinus Thrombosis: A Review
Autor: Aashish Gupta, John C. Lewin, Giuseppe Lippi, Partha Sardar, John G. Rizk, Brandon Michael Henry, Carl J. Lavie
Publikováno v: JAMA cardiology. 6(12)
Importance: The COVID-19 pandemic saw one of the fastest developments of vaccines in an effort to combat an out-of-control pandemic. The 2 most common COVID-19 vaccine platforms currently in use, messenger RNA (mRNA) and adenovirus vector, were devel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14038d25aa64e614a17c12f23a80e235
https://pubmed.ncbi.nlm.nih.gov/34374713
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4
Expanded Access Programs, compassionate drug use, and Emergency Use Authorizations during the COVID-19 pandemic
Autor: Youssef Rizk, Kamyar Kalantar-Zadeh, Mandeep R. Mehra, JoAnn P. Pfeiffer, John C. Lewin, Carl J. Lavie, Donald N. Forthal, John G. Rizk
Publikováno v: Drug discovery today, vol 26, iss 2
Drug Discovery Today
Highlights • Expanded Access (EA) is the use of an investigational drug outside of a clinical investigation. • Emergency Use Authorizations (EUAs) are issued during public health emergencies. • The pandemic has forced us to recognize weaknesses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7723f2ddbd374a61b5e40a7dcca9596
https://escholarship.org/uc/item/9p1571t6
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5
Improving Medication Adherence in Cardiometabolic Disease
Autor: Keith C. Ferdinand, Dennis R. Cryer, Samar A. Nasser, Helene D. Clayton-Jeter, John C. Lewin, Robert M. Califf, Fortunato Fred Senatore, Mona Fiuzat
Publikováno v: Journal of the American College of Cardiology. 69:437-451
Medication nonadherence, a major problem in cardiovascular disease (CVD), contributes yearly to approximately 125,000 preventable deaths, which is partly attributable to only about one-half of CVD patients consistently taking prescribed life-saving m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1565c52406262adbdf6d7345a8dfe072
https://doi.org/10.1016/j.jacc.2016.11.034
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6
Disparities in hypertension and cardiovascular disease in blacks: The critical role of medication adherence
Autor: Fortunato Fred Senatore, Samar A. Nasser, Keith C. Ferdinand, John C. Lewin, Dennis R. Cryer, Kapil Yadav, Helene D. Clayton-Jeter
Publikováno v: J Clin Hypertens (Greenwich)
Blacks are two to three times as likely as whites to die of preventable heart disease and stroke. Declines in mortality from heart disease have not eliminated racial disparities. Control and effective treatment of hypertension, a leading cause of car
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3471edcdcf1d167344c62b1f02c88e71
https://europepmc.org/articles/PMC5638710/
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8
Our Physicians and Our Profession Must Lead in Improving Our Health Care System
Autor: Arthur Garson, John C. Lewin, Carolyn L. Engelhard
Publikováno v: Journal of the American College of Cardiology. 55:2196-2200
Health care reform legislation has passed in Washington. The status quo was the worst of options, so this imperfect solution at least offers a sense of direction. As we know, true reform is about patients, practitioners, and the health of America. It
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b787e89943958a45d01752ef715cf13
https://doi.org/10.1016/j.jacc.2010.04.002
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9
The elusive path to health care sustainability
Autor: John C. Lewin, G. Lawrence Atkins, Larry McNeely
Publikováno v: JAMA. 310(16)
Despite the recent slowdown in health care inflation, particularly in Medicare and Medicaid, increases in health care costs threaten to exceed the nation�s capacity to pay. Medicare�s accountable care, medical home, and bundled payment initiative
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3d7df61d94ae39fabecc6ca2f92703
https://pubmed.ncbi.nlm.nih.gov/24080945
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10
Reflections on national health care reform based on Hawaii's experience
Autor: John C. Lewin
Publikováno v: The American Journal of Surgery. 167:227-231
In 1974, Hawaii began addressing the problem of health care accessibility. As a result of legislative action, near universal health care coverage has been achieved. These include employer mandates to provide adequate health insurance, regulation of i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69176a607263a867b7e9069828cdb143
https://doi.org/10.1016/0002-9610(94)90080-9
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