Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John C. Gill"'
Autor:
Silvia T. Erni, John C. Gill, Carlotta Palaferri, Gabriella Fernandes, Michelle Buri, Katherine Lazarides, Denis Grandgirard, Albert S. B. Edge, Stephen L. Leib, Marta Roccio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Sensorineural hearing loss is prevalent within society affecting the quality of life of 460 million worldwide. In the majority of cases, this is due to insult or degeneration of mechanosensory hair cells in the cochlea. In adult mammals, hair cell lo
Externí odkaz:
https://doaj.org/article/a5657b29045d44028d45c274ad89c520
Autor:
Silvia T. Erni, John C. Gill, Carlotta Palaferri, Gabriella Fernandes, Michelle Buri, Katherine Lazarides, Denis Grandgirard, Albert S. B. Edge, Stephen L. Leib, Marta Roccio
Publikováno v:
Erni, Silvia T.; Gill, John C.; Palaferri, Carlotta; Fernandes, Gabriella; Buri, Michelle; Lazarides, Katherine; Grandgirard, Denis; Edge, Albert S. B.; Leib, Stephen; Roccio, Marta (2021). Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors. Frontiers in cell and developmental biology, 9(2256) Frontiers 10.3389/fcell.2021.710159
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Sensorineural hearing loss is prevalent within society affecting the quality of life of 460 million worldwide. In the majority of cases, this is due to insult or degeneration of mechanosensory hair cells in the cochlea. In adult mammals, hair cell lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d6deeafd3eaf59a98fafb2632610c5
https://boris.unibe.ch/158164/1/fcell-09-710159.pdf
https://boris.unibe.ch/158164/1/fcell-09-710159.pdf
Autor:
Andrew Wolfe, John C. Gill, Caroline A Maguire, Ursula B. Kaiser, Víctor M. Navarro, Serap Simavli, Rona S. Carroll, Iain R. Thompson
Publikováno v:
Endocrinology. 156:2313-2322
Puberty is a tightly regulated process that leads to reproductive capacity. Kiss1 neurons are crucial in this process by stimulating GnRH, yet how Kiss1 neurons are regulated remains unknown. Substance P (SP), an important neuropeptide in pain percep
Autor:
Francis de Zegher, Ursula B. Kaiser, Víctor M. Navarro, Joel N. Hirschhorn, Vinicius Nahime Brito, Berenice B. Mendonca, Delanie B. Macedo, Rona S. Carroll, Sekoni D. Noel, Priscilla Cukier, Priscila Gagliardi, Cristiane Kochi, Ana Claudia Latronico, Tânia Rodrigues, Andrew Dauber, Dominique Beckers, Iain R. Thompson, Ana Paula Abreu, John C. Gill, Luciana Ribeiro Montenegro, Carlos Alberto Longui
Publikováno v:
New England Journal of Medicine. 368:2467-2475
Background: The onset of puberty is first detected as an increase in pulsatile secretion of gonado-tropin-releasing hormone (GnRH). Early activation of the hypothalamic-pituitary-gonadal axis results in central precocious puberty. The timing of puber
Autor:
Pei-San Tsai, John C. Gill
Publikováno v:
Biology of Reproduction. 74:463-472
During development, neurons that synthesize and release gonadotropin-releasing hormone (GNRH1) extend their axons to the median eminence (ME) to establish neurosecretory contacts necessary for hormone secretion. Signals that coordinate this process a
Autor:
Mohammed El Majdoubi, Richard I. Weiner, Sabine Werner, Hector Postigo, Suzanne M. Moenter, Toni R. Pak, Pei-San Tsai, Sreenivasan Paruthiyil, John C. Gill
Publikováno v:
Molecular Endocrinology. 19:225-236
Increasing evidence suggests that fibroblast growth factors (FGFs) are neurotrophic in GnRH neurons. However, the extent to which FGFs are involved in establishing a functional GnRH system in the whole organism has not been investigated. In this stud
Autor:
John C. Gill, Ursula B. Kaiser, Shuyun Xu, Cecilia Martin, Cecilia Kwong, Víctor M. Navarro, Rona S. Carroll, Donald K. Clifton, Sekoni D. Noel, Robert A. Steiner
Publikováno v:
Endocrinology. 153(10)
At puberty, neurokinin B (NKB) and kisspeptin (Kiss1) may help to amplify GnRH secretion, but their precise roles remain ambiguous. We tested the hypothesis that NKB and Kiss1 are induced as a function of pubertal development, independently of the pr
Autor:
Andrea Reyna, Gerald A. Schwarting, Elisa M. Jorgensen, Brandon Wadas, John C. Gill, Stuart A. Tobet, Suzanne M. Moenter, Shaila K. Mani, Ursula B. Kaiser, Wendy Portillo, Peilin Chen
Publikováno v:
Endocrinology. 149(9)
Hypothalamic GnRH neurons are essential for initiation and regulation of reproductive function. In addition to pituitary gonadotrope stimulation, activity of GnRH through its receptor (GnRHR) has been suggested to include autocrine regulation of the