Zobrazeno 1 - 10
of 91
pro vyhledávání: '"John C. Foreman"'
Publikováno v:
Current Opinion in Pharmacology. 5:214-220
The nasal actions of histamine were originally attributed to vascular and neuronal H(1) receptor activation. Recent studies have identified a H(3) receptor that contributes to histamine-induced inflammation via the inhibition of sympathetic activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da089d55cc061623f03fbb49070a741
https://doi.org/10.1016/j.coph.2004.12.004
https://doi.org/10.1016/j.coph.2004.12.004
Publikováno v:
British Journal of Pharmacology. 144:867-874
1. The aim of this study was to investigate the mechanisms by which histamine causes nasal blockage. Histamine, 40-800 microg, intranasally into each nostril, induced significant blockage of the nasal airway in normal human subjects, as measured by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::555ce52189b46233620d150296c12cb1
https://doi.org/10.1038/sj.bjp.0706118
https://doi.org/10.1038/sj.bjp.0706118
Autor:
Matthew E. Handley, Manika Chaudry, Peter R Bunyard, Gabriel Pollara, John C. Foreman, David R. Katz, Charles J.J Alderman, Isabelle Wood, Benjamin M. Chain, Karine Rutault
Publikováno v:
Molecular Immunology. 39:815-827
Initiation of adaptive immunity requires activation of dendritic cells (DC) by "danger" signals. This study examines the functional consequences of activating a cellular stress response in human DC. Anisomycin, a potent inducer of this "stress" respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3e0a89a184f1ac0bd9910bc2c4217c
https://doi.org/10.1016/s0161-5890(02)00262-6
https://doi.org/10.1016/s0161-5890(02)00262-6
Publikováno v:
British Journal of Pharmacology. 131:363-369
The effects of inhibitors of nitric oxide synthase (NOS) on the responsiveness of the human nasal airway were investigated, by measuring the nasal response to histamine and bradykinin. Repeated intranasal administration of NG-nitro-L-arginine methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::708d7967087e45af64420f4b2ac286e5
https://doi.org/10.1038/sj.bjp.0703561
https://doi.org/10.1038/sj.bjp.0703561
Publikováno v:
British Journal of Pharmacology. 129:525-532
1. The aim of this study was to investigate the role of kinins in the development of nasal hyperresponsiveness induced by platelet activating factor (PAF) in normal human subjects. 2. Intranasal administration of PAF, 60 micrograms, induced an increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8b964f21b708c572c6ad4e83d5e7ce6
https://doi.org/10.1038/sj.bjp.0703095
https://doi.org/10.1038/sj.bjp.0703095
Publikováno v:
British Journal of Pharmacology. 122:1188-1194
1 We have examined the role of extracellular chloride in the mast cell secretion process. The immunologically-directed ligand, antibody to IgE (anti-IgE) required extracellular chloride ions for optimum secretion from rat peritoneal mast cells. In co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8710353995605c01da63a7c51a0edeb6
https://doi.org/10.1038/sj.bjp.0701418
https://doi.org/10.1038/sj.bjp.0701418
Publikováno v:
British Journal of Dermatology. 134:399-406
It has been argued that the digital cutaneous microvasculature is the site of the anomaly which causes Raynaud's phenomenon (RP). Both endothelin-1 (ET-1), a potent vasoconstrictor peptide present in the digital cutaneous microvasculature, and calcit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66db9f45edaf2841ad7dfe0f6121ca13
https://doi.org/10.1046/j.1365-2133.1996.22757.x
https://doi.org/10.1046/j.1365-2133.1996.22757.x
Publikováno v:
Europe PubMed Central
The effect of topical application of clobetasol propionate ointment (0.05% w/v) on the vascular changes induced by intradermal injections of histamine, calcitonin gene-related peptide, substance P, endothelin-1 and compound 48/80 was studied. Clobeta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc0d3e548ea2a56f3466b561f02c931
https://doi.org/10.1159/000211427
https://doi.org/10.1159/000211427
Publikováno v:
Europe PubMed Central
The aim of this study was to investigate in human skin in vivo the role of nitric oxide in maintaining resting vascular tone, in the vasodilatation caused by local warming and by ultraviolet B light exposure, and in the response to exogenous calciton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf5c81982e27eda1488eb714855eff1
https://doi.org/10.1111/1523-1747.ep12328204
https://doi.org/10.1111/1523-1747.ep12328204
For the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from a renowned course on receptor pharmacology, this text presents in-depth coverage of this rapidly expanding research area. Th
