Zobrazeno 1 - 7 of 7 pro vyhledávání: '"John C. Fanaras"'
2
Use of high-pH (basic/alkaline) mobile phases for LC-MS or LC-MS/MS bioanalysis
Autor: John C. Fanaras, Aimin Tan
Publikováno v: Biomedical chromatography : BMC. 33(1)
High-pH or basic/alkaline mobile phases are not commonly used in LC-MS or LC-MS/MS bioanalysis because of the deeply rooted concern with column instability and reduced detection sensitivity for basic compounds in high-pH mobile phases owing to charge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f63cf6660f3ced2c9e39e9c052742a
https://pubmed.ncbi.nlm.nih.gov/30315658
Zobrazit plný text záznamu
3
How much separation for LC-MS/MS quantitative bioanalysis of drugs and metabolites?
Autor: Aimin Tan, John C. Fanaras
Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1084
LC-MS/MS has been the dominant analytical technology for quantitative bioanalysis of drugs and metabolites for more than two decades. Despite this, a very fundamental question like how much separation is required for LC-MS/MS quantitative bioanalysis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788674000739a24dd6f36c99a3b5021f
https://pubmed.ncbi.nlm.nih.gov/29558737
Zobrazit plný text záznamu
4
Improving the selectivity and sensitivity for quantifying 8-α-hydroxy-mutilin in rabbit tissues by using basic mobile phases and negative ionization
Autor: Gordon T. Bolger, Guifen Gu, Yanxin Wu, Aimin Tan, John C. Fanaras, Xuan Gui, Albert Licollari
Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1072
Previously reported LC–MS methods for quantifying 8-α-hydroxy-mutilin (a marker residue of tiamulin) in tissues all used a pseudo MRM transition (from protonated molecular ion to protonated molecular ion, m/z 337 → 337) due to difficulties in fi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e1dda343f46f40b98a48a81af77070
https://pubmed.ncbi.nlm.nih.gov/29153999
Zobrazit plný text záznamu
6
Self-initiated and concentration-dependent degradation of tetracaine in neat standard solutions: A trouble-shooting story
Autor: Aimin Tan, Yanxin Wu, Guifen Gu, John C. Fanaras
Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
This paper presents the trouble-shooting for a very unusual stability case. Tetracaine was found unstable in neat solutions only at high concentrations, but not at low concentrations. Moreover, its stable-isotope labeled internal standard did not sho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b889969a5f64197eca2f8f1a4206a694
https://pubmed.ncbi.nlm.nih.gov/27541625
Zobrazit plný text záznamu
7
Use of basic mobile phase to improve chromatography and boost sensitivity for quantifying tetrahydrocurcumin in human plasma by LC-MS/MS
Autor: Albert Licollari, Lawrence Helson, George M. Shopp, Aimin Tan, John C. Fanaras, Yanxin Wu, Molly Wong, Gordon T. Bolger
Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1028
Tetrahydrocurcumin (THC), a major metabolite of curcumin, is often quantified by LC-MS or LC-MS/MS using acidic mobile phases due to the concern of its instability in a basic medium. However, acidic mobile phases often lead to poor chromatography (e.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d9b84f56147e17ca3de6b4f25b03a1
https://pubmed.ncbi.nlm.nih.gov/27327398
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje