Zobrazeno 1 - 10
of 46
pro vyhledávání: '"John C. Dowdy"'
Autor:
Robert C. Tuckey, Sherie Hanna, Robert M. Sayre, John C. Dowdy, Tae Kang Kim, Andrzej Slominski, Zorica Janjetovic, Wei Li, Sofia Rosas, Piotr Wasilewski
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 148:52-63
CYP11A1 hydroxylates the side chain of vitamin D3 (D3) in a sequential fashion [D3→20S(OH)D3→20,23(OH)2D3→17,20,23(OH)3D3], in an alternative to the classical pathway of activation [D3→25(OH)D3→1,25(OH)2D3]. The products/intermediates of th
Autor:
Robert M. Sayre, John C. Dowdy
Publikováno v:
Photochemistry and Photobiology. 89:961-967
We evaluated six UV nail lamps representative of major US manufacturers to evaluate radiant hazards as defined in ANSI/IESNA RP-27 Recommended Practice for Photobiological Safety. Lamps were evaluated at three positions, 1 cm above the inner surface
Publikováno v:
British Journal of Dermatology. 168:595-601
Background—11β-hydroxysteroid dehydrogenase type 1 (HSD11B1), 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2), glucocorticoids (GC) and their receptor (GR) play a key role in tissue-specific regulation of GC action. Objectives—The expression
Autor:
Gregory Richard Bender, Kenneth D. Shinneman, John C. Dowdy, Lateef U. Khan, James G. Shepherd, Steven C. Schlitt, Eugene A. Czako, Robert M. Sayre, Michael E. Stepp, Manuel G. Karos
Publikováno v:
Health Physics. 101:227-232
The authors compared calculations of sunlamp maximum exposure times following current USFDA Guidance Policy on the Maximum Timer Interval and Exposure Schedule, with USFDA/CDRH proposals revising these to equivalent erythemal exposures of ISO/CIE Sta
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 301:E484-E493
The hypothalamic-pituitary-adrenal (HPA) axis maintains basal and stress-related homeostasis in vertebrates. Skin expresses all elements of the HPA axis including corticotropin-releasing hormone (CRH), proopiomelanocortin (POMC), ACTH, β-endorphin (
Autor:
Robert M. Sayre, John C. Dowdy
Publikováno v:
Photochemical & Photobiological Sciences. 9:535-539
The US Food and Drug Administration is in the process of formulating final rules for sunscreen labeling and testing. They have adopted a version of the solar simulator standard proposed by COLIPA, a European cosmetic products trade association. From
Autor:
John C. Dowdy, Robert M. Sayre
Publikováno v:
Photochemistry and Photobiology. 86:162-167
The U.S. FDA recently proposed both in vivo and in vitro UVA efficacy tests for sunscreen products with the lower result used to establish the sunscreen's labeled UVA protection claim. The FDA stated their rationale for dual tests was concern that th
Publikováno v:
Photodermatology, Photoimmunology & Photomedicine. 25:216-220
In 1979 the Food and Drug Administration (FDA) designated indoor tanning units would be regulated medical devices and that each must have an exposure timer. In 1985 FDA added a scheduled series of doses designed to allow tanning with little risk of c
Publikováno v:
Photochemistry and Photobiology. 85:1004-1010
Ultraviolet radiation (UVR) is hazardous to patients with photosensitive skin disorders, such as lupus erythematosus, xeroderma pigmentosum and skin cancer. As such, these patients are advised to minimize their exposure to UVR. Classically, this is a
Autor:
Mitchell A. Watsky, Nathaniel K. Wilkin, Karl T. Weber, Thomas A. Hughes, E. William Rosenberg, Tai C. Chen, Laura D Carbone, Syamal K. Bhattacharya, Michael F. Holick, John C. Dowdy, Elizabeth A. Tolley, Robert M. Sayre, Karen D. Barrow
Publikováno v:
Metabolism. 57:741-748
Vitamin D deficiency may have implications for cardiovascular health. The purpose of this study was to determine the relationship of 25-hydroxyvitamin D (25[OH]D) to cholesterol and lipoprotein particles and to determine whether increasing 25(OH)D th