A worldwide study of white matter microstructural alterations in people living with Parkinson’s disease

Autor: Conor Owens-Walton, Talia M. Nir, Sarah Al-Bachari, Sonia Ambrogi, Tim J. Anderson, Ítalo Karmann Aventurato, Fernando Cendes, Yao-Liang Chen, Valentina Ciullo, Phil Cook, John C. Dalrymple-Alford, Michiel F. Dirkx, Jason Druzgal, Hedley C. A. Emsley, Rachel Guimarães, Hamied A. Haroon, Rick C. Helmich, Michele T. Hu, Martin E. Johansson, Ho Bin Kim, Johannes C. Klein, Max Laansma, Katherine E. Lawrence, Christine Lochner, Clare Mackay, Corey T. McMillan, Tracy R. Melzer, Leila Nabulsi, Ben Newman, Peter Opriessnig, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Federica Piras, Lukas Pirpamer, Toni L. Pitcher, Kathleen L. Poston, Annerine Roos, Lucas Scárdua Silva, Reinhold Schmidt, Petra Schwingenschuh, Marian Shahid-Besanti, Gianfranco Spalletta, Dan J. Stein, Sophia I. Thomopoulos, Duygu Tosun, Chih-Chien Tsai, Odile A. van den Heuvel, Eva van Heese, Daniela Vecchio, Julio E. Villalón-Reina, Chris Vriend, Jiun-Jie Wang, Yih-Ru Wu, Clarissa Lin Yasuda, Paul M. Thompson, Neda Jahanshad, Ysbrand van der Werf

Publikováno v: npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)

Abstract The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous met

Externí odkaz: https://doaj.org/article/abdb13d4596d46599f5bc49288648bf9

Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis

Autor: Eamonn Kennedy, Spencer W. Liebel, Hannah M. Lindsey, Shashank Vadlamani, Pui-Wa Lei, Maheen M. Adamson, Martin Alda, Silvia Alonso-Lana, Tim J. Anderson, Celso Arango, Robert F. Asarnow, Mihai Avram, Rosa Ayesa-Arriola, Talin Babikian, Nerisa Banaj, Laura J. Bird, Stefan Borgwardt, Amy Brodtmann, Katharina Brosch, Karen Caeyenberghs, Vince D. Calhoun, Nancy D. Chiaravalloti, David X. Cifu, Benedicto Crespo-Facorro, John C. Dalrymple-Alford, Kristen Dams-O’Connor, Udo Dannlowski, David Darby, Nicholas Davenport, John DeLuca, Covadonga M. Diaz-Caneja, Seth G. Disner, Ekaterina Dobryakova, Stefan Ehrlich, Carrie Esopenko, Fabio Ferrarelli, Lea E. Frank, Carol E. Franz, Paola Fuentes-Claramonte, Helen Genova, Christopher C. Giza, Janik Goltermann, Dominik Grotegerd, Marius Gruber, Alfonso Gutierrez-Zotes, Minji Ha, Jan Haavik, Charles Hinkin, Kristen R. Hoskinson, Daniela Hubl, Andrei Irimia, Andreas Jansen, Michael Kaess, Xiaojian Kang, Kimbra Kenney, Barbora Keřková, Mohamed Salah Khlif, Minah Kim, Jochen Kindler, Tilo Kircher, Karolina Knížková, Knut K. Kolskår, Denise Krch, William S. Kremen, Taylor Kuhn, Veena Kumari, Junsoo Kwon, Roberto Langella, Sarah Laskowitz, Jungha Lee, Jean Lengenfelder, Victoria Liou-Johnson, Sara M. Lippa, Marianne Løvstad, Astri J. Lundervold, Cassandra Marotta, Craig A. Marquardt, Paulo Mattos, Ahmad Mayeli, Carrie R. McDonald, Susanne Meinert, Tracy R. Melzer, Jessica Merchán-Naranjo, Chantal Michel, Rajendra A. Morey, Benson Mwangi, Daniel J. Myall, Igor Nenadić, Mary R. Newsome, Abraham Nunes, Terence O’Brien, Viola Oertel, John Ollinger, Alexander Olsen, Victor Ortiz García de la Foz, Mustafa Ozmen, Heath Pardoe, Marise Parent, Fabrizio Piras, Federica Piras, Edith Pomarol-Clotet, Jonathan Repple, Geneviève Richard, Jonathan Rodriguez, Mabel Rodriguez, Kelly Rootes-Murdy, Jared Rowland, Nicholas P. Ryan, Raymond Salvador, Anne-Marthe Sanders, Andre Schmidt, Jair C. Soares, Gianfranco Spalleta, Filip Španiel, Scott R. Sponheim, Alena Stasenko, Frederike Stein, Benjamin Straube, April Thames, Florian Thomas-Odenthal, Sophia I. Thomopoulos, Erin B. Tone, Ivan Torres, Maya Troyanskaya, Jessica A. Turner, Kristine M. Ulrichsen, Guillermo Umpierrez, Daniela Vecchio, Elisabet Vilella, Lucy Vivash, William C. Walker, Emilio Werden, Lars T. Westlye, Krista Wild, Adrian Wroblewski, Mon-Ju Wu, Glenn R. Wylie, Lakshmi N. Yatham, Giovana B. Zunta-Soares, Paul M. Thompson, Mary Jo Pugh, David F. Tate, Frank G. Hillary, Elisabeth A. Wilde, Emily L. Dennis

Publikováno v: Brain Sciences, Vol 14, Iss 7, p 669 (2024)

Deficits in memory performance have been linked to a wide range of neurological and neuropsychiatric conditions. While many studies have assessed the memory impacts of individual conditions, this study considers a broader perspective by evaluating ho

Externí odkaz: https://doaj.org/article/1cd9cc3673eb4e819bd68e603b342672

Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia

Autor: Catherine A. Morgan, Tracy R. Melzer, Reece P. Roberts, Kristina Wiebels, Henk J. M. M. Mutsaerts, Meg J. Spriggs, John C. Dalrymple-Alford, Tim J. Anderson, Nicholas J. Cutfield, Gerard Deib, Josef Pfeuffer, Donna Rose Addis, Ian J. Kirk, Lynette J. Tippett

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract Cerebral blood flow (CBF) measured with arterial spin labelling (ASL) magnetic resonance imaging (MRI) reflects cerebral perfusion, related to metabolism, and arterial transit time (ATT), related to vascular health. Our aim was to investigat

Externí odkaz: https://doaj.org/article/ac1ca4472f9c46c8bd930dfcadba90c1

Beta Amyloid Deposition Is Not Associated With Cognitive Impairment in Parkinson's Disease

Autor: Tracy R. Melzer, Megan R. Stark, Ross J. Keenan, Daniel J. Myall, Michael R. MacAskill, Toni L. Pitcher, Leslie Livingston, Sophie Grenfell, Kyla-Louise Horne, Bob N. Young, Maddie J. Pascoe, Mustafa M. Almuqbel, Jian Wang, Steven H. Marsh, David H. Miller, John C. Dalrymple-Alford, Tim J. Anderson

Publikováno v: Frontiers in Neurology, Vol 10 (2019)

The extent to which Alzheimer neuropathology, particularly the accumulation of misfolded beta-amyloid, contributes to cognitive decline and dementia in Parkinson's disease (PD) is unresolved. Here, we used Florbetaben PET imaging to test for any asso

Externí odkaz: https://doaj.org/article/5e3a8878de6b4d3c85dea8ac4d98eeda

Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats

Autor: Susan A. Rapley, Timothy C. R. Prickett, John C. Dalrymple-Alford, Eric A. Espiner

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 12 (2018)

Beneficial molecular and neuroplastic changes have been demonstrated in response to environmental enrichment (EE) in laboratory animals across the lifespan. Here, we investigated whether these effects extend to C-type Natriuretic Peptide (CNP), a wid

Externí odkaz: https://doaj.org/article/4a60c9dfc6a741b2b4aaa6e9ac431c62