Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John C. Chapin"'
Autor:
Bruce Ewenstein, Maurus de la Rosa, Barbara A. Konkle, Ivan Bilic, Birgit M. Reipert, Paul E. Monahan, Scott W.J. McPhee, R. Jude Samulski, Hanspeter Rottensteiner, Miguel A. Escobar, Neil C. Josephson, John C. Chapin, Friedrich Scheiflinger, Annette von Drygalski, Guy Young, Christopher E. Walsh
Publikováno v:
Blood
Gene therapy has the potential to maintain therapeutic blood clotting factor IX (FIX) levels in patients with hemophilia B by delivering a functional human F9 gene into liver cells. This phase 1/2, open-label dose-escalation study investigated BAX 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8ff7d5209306c46cbe07c2ddd9a785
https://doi.org/10.1182/blood.2019004625
https://doi.org/10.1182/blood.2019004625
Autor:
John C. Chapin
Publikováno v:
Clinical Interventions in Aging
Von Willebrand disease (VWD) is an inherited bleeding disorder that affects up to 1% of the population. In most cases, VWD results from a mutation in the von Willebrand Factor (VWF) gene, which alters the amount and function of VWF, a key glycoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527ee3dea7f49852ded93b1671805d65
https://doi.org/10.2147/cia.s136931
https://doi.org/10.2147/cia.s136931
Autor:
John C. Chapin
This publication traces more than 40 years of active service by Marine Fighter Attack Squadron 115. Since its commissioning in July 1943 the squadron has evolved from a group of wartime beginners in SNJ-4 planes to front line professionals in their F
Autor:
John C. Chapin, Paul E. Monahan
Publikováno v:
BioDrugs. 32:9-25
Hemophilia is a congenital bleeding disorder that affects nearly half a million individuals worldwide. Joint bleeding and other co-morbidities are a significant source of debilitation for this population. Current therapies are effective but must be g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cd8a43fa7d57976ffe42833e8a6cfb
https://doi.org/10.1007/s40259-017-0255-0
https://doi.org/10.1007/s40259-017-0255-0
Autor:
1st Lieut. John C. Chapin
The major ground component of the active Marine Corps Reserve is the 4th Marine Division, Fleet Marine Force. The combat record of this division in World War II was exemplary; in the short space of one year it participated in four major amphibious as
Publikováno v:
Blood. 132:5794-5794
Introduction: Adeno-associated virus (AAV) is a versatile gene therapy vector utilized widely in clinical gene transfer studies. AAV serotype 8 (AAV8) has been used successfully as a vector in liver-directed gene transfer in hemophilia clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f18c0bbca4a6a2265d5f4e65202e5b08
https://doi.org/10.1182/blood-2018-99-113308
https://doi.org/10.1182/blood-2018-99-113308
Autor:
John C. Chapin, Terry Adams
Publikováno v:
Opflow. 37:24-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af61a97864dd4647e5d70b2c1ff421a3
https://doi.org/10.1002/j.1551-8701.2011.tb03099.x
https://doi.org/10.1002/j.1551-8701.2011.tb03099.x
Publikováno v:
Blood. 122:1120-1120
Introduction Adults with hemophilia and von Willebrand disease (VWD) frequently require surgical and invasive procedures. There is variability in current practice of peri-operative management in major surgery and in the management of invasive procedu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6451bfb90ffcbbbfc8e03361370362dd
https://doi.org/10.1182/blood.v122.21.1120.1120
https://doi.org/10.1182/blood.v122.21.1120.1120