Zobrazeno 1 - 10
of 23
pro vyhledávání: '"John C. Booth"'
Autor:
Stella Y. Sun, Li-av Segev-Zarko, Grigore D. Pintilie, Chi Yong Kim, Sophia R. Staggers, Michael F. Schmid, Elizabeth S. Egan, Wah Chiu, John C. Boothroyd
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTIntracellular infectious agents, like the malaria parasite, Plasmodium falciparum, face the daunting challenge of how to invade a host cell. This problem may be even harder when the host cell in question is the enucleated red blood cell, whic
Externí odkaz:
https://doaj.org/article/f2cedbf4a5ab40b29e18a4902372d612
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT Toxoplasma gondii is an obligate, intracellular parasite. Infection of a cell produces a unique niche for the parasite named the parasitophorous vacuole (PV) initially composed of host plasma membrane invaginated during invasion. The PV and
Externí odkaz:
https://doaj.org/article/76db4ae80b0b4c5097d89e961faf15b8
Autor:
Cheryl E. Seifert, John C. Booth, Kathy N. Speechley, Larry W. Stitt, Patricia A. McGrath, Margaret C. Gibson
Publikováno v:
Pain. 64:435-443
A new instrument was designed to provide a practical clinical measure for assessing children's pain intensity and pain affect. The pocket size measure includes a Coloured Analogue Scale (CAS) to assess intensity and a facial affective scale to assess
Autor:
Debbie A Cramb, John C. Booth
Publikováno v:
Hearing Research. 52:312-320
This study examined the pattern of intensity integration at threshold. The stimuli studied are unique in that they have a compound peak-to-peak amplitude envelope. This waveform was partitioned into two segments, each having a different peak-to-peak
Publikováno v:
The Journal of the Acoustical Society of America. 113(4 Pt 1)
Individual variations in head and outer ear size, as well as growth of these structures during development, can markedly alter the values of the binaural and monaural cues which form the basis for auditory localization. This study investigated indivi
Autor:
Terence C. Theisen, John C. Boothroyd
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
Toxoplasma gondii has numerous, large, paralogous gene families that are likely critical for supporting its unparalleled host range: nearly any nucleated cell in almost any warm-blooded animal. The SRS (SAG1-related sequence) gene family encodes over
Externí odkaz:
https://doaj.org/article/41272668fec14f289a76a914327fe9ad
Autor:
Alicja M. Cygan, Pierre M. Jean Beltran, Alma G. Mendoza, Tess C. Branon, Alice Y. Ting, Steven A. Carr, John C. Boothroyd
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Toxoplasma gondii is a ubiquitous, intracellular parasite that envelops its parasitophorous vacuole with a protein-laden membrane (PVM). The PVM is critical for interactions with the infected host cell, such as nutrient transport and immune
Externí odkaz:
https://doaj.org/article/7d01b8bad4c74229ad4e7c136d69e96e
Autor:
Michael W. Panas, John C. Boothroyd
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Manipulation of the host cell is a crucial part of life for many intracellular organisms. We have recently come to appreciate the extent to which the intracellular pathogen Toxoplasma gondii reprograms its host cell, and this is illustrated
Externí odkaz:
https://doaj.org/article/7a6c274a0fac4f598d1cfe1ea0ef747f
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT The intracellular parasite Toxoplasma gondii employs a vast array of effector proteins from the rhoptry and dense granule organelles to modulate host cell biology; these effectors are known as ROPs and GRAs, respectively. To examine the indi
Externí odkaz:
https://doaj.org/article/03eae627a1cc42e2baa6737e3792e041
Autor:
Alicja M. Cygan, Terence C. Theisen, Alma G. Mendoza, Nicole D. Marino, Michael W. Panas, John C. Boothroyd
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Toxoplasma gondii is a ubiquitous, intracellular protozoan that extensively modifies infected host cells through secreted effector proteins. Many such effectors must be translocated across the parasitophorous vacuole (PV), in which the paras
Externí odkaz:
https://doaj.org/article/fb57c53858b645e2bbf85eb47a76cc35