Zobrazeno 1 - 9
of 9
pro vyhledávání: '"John C. Athey"'
Autor:
Aikaterini Alexaki, Jacob Kames, Gaya K. Hettiarachchi, John C. Athey, Upendra K. Katneni, Ryan C. Hunt, Nobuko Hamasaki-Katagiri, David D. Holcomb, Michael DiCuccio, Haim Bar, Anton A. Komar, Chava Kimchi-Sarfaty
Publikováno v:
F1000Research, Vol 9 (2020)
Ribosome profiling provides the opportunity to evaluate translation kinetics at codon level resolution. Here, we describe ribosome profiling data, generated from two HEK293T cell lines. The ribosome profiling data are composed of Ribo-seq (mRNA seque
Externí odkaz:
https://doaj.org/article/1a80c3483ae443bb80de7ba5bc14c567
Autor:
Upendra K. Katneni, Aikaterini Alexaki, Ryan C. Hunt, Nobuko Hamasaki-Katagiri, Gaya K. Hettiarachchi, Jacob M. Kames, Joseph R. McGill, David D. Holcomb, John C. Athey, Brian Lin, Leonid A. Parunov, Tal Kafri, Qi Lu, Robert Peters, Mikhail V. Ovanesov, Darón I. Freedberg, Haim Bar, Anton A. Komar, Zuben E. Sauna, Chava Kimchi-Sarfaty
Publikováno v:
Blood advances. 6(13)
Hemophilia B is a blood clotting disorder caused by deficient activity of coagulation factor IX (FIX). Multiple recombinant FIX proteins are currently approved to treat hemophilia B, and several gene therapy products are currently being developed. Co
Autor:
Darón I. Freedberg, David D. Holcomb, Ryan C. Hunt, Kazuyo Takeda, Amy D. Gelinas, Dougald M. Monroe, Puja Nanavaty, Robert Peters, John C. Athey, Zuben E. Sauna, Vijaya L. Simhadri, Aikaterini Alexaki, Nebojsa Janjic, Nobuko Hamasaki-Katagiri, Joseph R. McGill, Michael DiCuccio, Upendra K. Katneni, Jacob Kames, Haim Bar, Anton A. Komar, Gaya K. Hettiarachchi, Brian Lin, Chava Kimchi-Sarfaty
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Synonymous codons occur with different frequencies in different organisms, a phenomenon termed codon usage bias. Codon optimization, a common term for a variety of approaches used widely by the biopharmaceutical industry, involves synonymous substitu
Autor:
John C. Athey, Jacob Kames, Zuben E. Sauna, Haim Bar, Gaya K. Hettiarachchi, Joseph R. McGill, Upendra K. Katneni, Ryan C. Hunt, Juan C. Ibla, Chava Kimchi-Sarfaty
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
The liver is the primary source of a large number of plasma proteins and plays a critical role in multiple biological processes. Inadequate oxygen supply characterizing various clinical settings such as liver transplantation exposes the liver to hypo
Autor:
Nobuko Hamasaki-Katagiri, Anton A. Komar, John C. Athey, Aikaterini Alexaki, Luis V. Santana-Quintero, Phuc Vihn Nguyen Lam, Jacob Kames, David D. Holcomb, Haim Bar, Ekaterina Osipova, Vahan Simonyan, Chava Kimchi-Sarfaty
Publikováno v:
Journal of Molecular Biology. 431:2434-2441
Usage of sequential codon-pairs is non-random and unique to each species. Codon-pair bias is related to but clearly distinct from individual codon usage bias. Codon-pair bias is thought to affect translational fidelity and efficiency and is presumed
Autor:
Aikaterini Alexaki, Jacob Kames, Haim Bar, Juan C. Ibla, Luis V. Santana-Quintero, Chava Kimchi-Sarfaty, Nobuko Hamasaki-Katagiri, Upendra K. Katneni, Anton Golikov, David D. Holcomb, John C. Athey
Publikováno v:
Journal of molecular biology. 432(11)
Protein expression in multicellular organisms varies widely across tissues. Codon usage in the transcriptome of each tissue is derived from genomic codon usage and the relative expression level of each gene. We created a comprehensive computational r
Autor:
Nobuko Hamasaki-Katagiri, Aikaterini Alexaki, Michael DiCuccio, Gaya K. Hettiarachchi, Jacob Kames, Chava Kimchi-Sarfaty, Haim Bar, Ryan C. Hunt, Upendra K. Katneni, David D. Holcomb, John C. Athey, Anton A. Komar
Publikováno v:
F1000Research
Ribosome profiling provides the opportunity to evaluate translation kinetics at codon level resolution. Here, we describe ribosome profiling data, generated from two HEK293T cell lines. The ribosome profiling data are composed of Ribo-seq (mRNA seque
Autor:
Upendra K. Katneni, John C. Athey, Aikaterini Alexaki, Vahan Simonyan, Ekaterina Osipova, Alexandre Rostovtsev, Luis V. Santana-Quintero, Chava Kimchi-Sarfaty
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-10 (2017)
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-10 (2017)
Background Due to the degeneracy of the genetic code, most amino acids can be encoded by multiple synonymous codons. Synonymous codons naturally occur with different frequencies in different organisms. The choice of codons may affect protein expressi
Autor:
Yan Zhao, John C. Athey, Brady J. Gaynor, Ellen L. Dally, Robert E. Davis, Jonathan Shao, Nigel A. Harrison, Gail E. Gasparich, Nicole M. Donofrio
Publikováno v:
Genome Announcements
Spiroplasma kunkelii causes corn stunt disease of Zea mays L. in the Americas. Here, we report the nucleotide sequence of the 1,463,926-bp circular chromosome and four plasmids of strain CR2-3x. This information will facilitate studies of Spiroplasma