Zobrazeno 1 - 10
of 46
pro vyhledávání: '"John C Rockett"'
Publikováno v:
Systems Biology in Reproductive Medicine. 55:214-226
Environmental chemicals that alter steroid production could interfere with male reproductive development and function. Three agricultural antifungal triazoles that are known to modulate expression of cytochrome P450 (CYP) genes and enzymatic activiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f001a6ffddae2590504d79fe7b64539a
https://doi.org/10.3109/19396360903234045
https://doi.org/10.3109/19396360903234045
Autor:
Jane E. Gallagher, Judith E. Schmid, Rachel N. Murrell, S. J. Kim, David J. Dix, John C Rockett, Kary E. Thompson
Publikováno v:
Clinical Chemistry. 53:1038-1045
Background: Gene expression profiling of whole blood may be useful for monitoring toxicological exposure and for diagnosis and monitoring of various diseases. Several methods are available that can be used to transport, store, and extract RNA from wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fea2d51d07eb8c1602e8297044cf16b
https://doi.org/10.1373/clinchem.2006.078436
https://doi.org/10.1373/clinchem.2006.078436
Autor:
Michael P. Diamond, David J. Dix, John C Rockett, Silvina Quintana, Stephen A. Krawetz, Vanesa Y. Rawe, Adrian E. Platts, Héctor E. Chemes, Kary E. Thompson, Lillian F. Strader, Robert Goodrich
Publikováno v:
Human Molecular Genetics. 16:763-773
We are coming to appreciate that at fertilization human spermatozoa deliver the paternal genome alongside a suite of structures, proteins and RNAs. Although the role of some of the structures and proteins as requisite elements for early human develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeafa89434993bf2471b756a151d3df6
https://doi.org/10.1093/hmg/ddm012
https://doi.org/10.1093/hmg/ddm012
Autor:
Michael G. Narotsky, Carmen R. Wood, Judith E. Schmid, Chad R. Blystone, Hongzu Ren, Wenjun Bao, Deborah S. Best, David J. Dix, John C Rockett, Amber K. Goetz, Douglas C. Wolf, Douglas B. Tully, Lillian F. Strader
Publikováno v:
Toxicology and Applied Pharmacology. 215:260-273
Four triazole fungicides were studied using toxicogenomic techniques to identify potential mechanisms of action. Adult male Sprague-Dawley rats were dosed for 14 days by gavage with fluconazole, myclobutanil, propiconazole, or triadimefon. Following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7a05404a1adb54d46c9d995825fd4d
https://doi.org/10.1016/j.taap.2006.02.015
https://doi.org/10.1016/j.taap.2006.02.015
Autor:
Charles D. Eads, Carrie M. Furnish, John C Rockett, Hector C. Keun, Drew R. Ekman, David J. Dix, Rachel N. Murrell
Publikováno v:
Metabolomics. 2:63-73
The effects of two triazole fungicides, myclobutanil and triadimefon, on endogenous rat metabolite profiles in blood serum, liver, and testis was assessed using proton nuclear magnetic resonance (1H-NMR) spectroscopy. Adult male Sprague-Dawley rats w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc84a3f4bb9e7e4bc9d81ed2e6e15cd8
https://doi.org/10.1007/s11306-006-0020-8
https://doi.org/10.1007/s11306-006-0020-8
Autor:
Christopher J. Roberts, Roger G. Ulrich, Paul D. Cornwell, Xudong Dai, Thomas H. Rushmore, John C. Castle, Yudong He, A. De Souza, R. Evers, D. Hartley, Michelle J. Caguyong, John C Rockett, Olivia Cheng, R. Hu, J. G. Slatter
Publikováno v:
Xenobiotica. 36:902-937
To examine species-specific aspects of the induction of absorption, distribution, metabolism and excretion (ADME)-related genes, we used 25 000 gene oligonucleotide microarrays to construct a rodent gene-response compendium that compared hepatic gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed395f3e55fd2958d56a37d103c67163
https://doi.org/10.1080/00498250600861694
https://doi.org/10.1080/00498250600861694
Autor:
J. Christopher Luft, Douglas B. Tully, John C Rockett, David J. Dix, Judith E. Schmid, Carmen R. Wood, Hongzu Ren
Publikováno v:
Reproductive Toxicology. 19:353-366
A byproduct of drinking water disinfection, bromochloroacetic acid (BCA), acts as a reproductive toxicant in rats. To determine if BCA produces similar reproductive toxicity in mice, juvenile and adult C57BL/6 males were exposed to 0, 8, 24, 72 or 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948853fceadbc4c25f991b6b886615fc
https://doi.org/10.1016/j.reprotox.2004.06.009
https://doi.org/10.1016/j.reprotox.2004.06.009
Autor:
Gary M. Hellmann, John C Rockett
Publikováno v:
Genomics
The generation of corroborative data has become a commonly used approach for ensuring the veracity of microarray data. Indeed, the need to conduct corroborative studies has now become official editorial policy for at least 2 journals, and several mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce49af24a9578045e951b0046cfaa4b
https://doi.org/10.1016/j.ygeno.2003.09.017
https://doi.org/10.1016/j.ygeno.2003.09.017
Publikováno v:
Environmental Health Perspectives
Detection, quantification, and prognosis of environmental exposures in humans has been vastly enhanced by the ability of epidemiologists to collect biospecimens for toxicologic or other laboratory evaluation. Ease of collection and level of invasiven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c24040bec27411d75e8936a9828839
http://europepmc.org/articles/PMC1241803
http://europepmc.org/articles/PMC1241803
Publikováno v:
Environmental Health Perspectives
DNA microarrays and related tools offer promise for identification of pathways involved in toxic responses to xenobiotics. To be useful for risk assessment, experimental data must be challenged for reliability and interlaboratory reproducibility. Tow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86de86784c6172d2114db66d3dee10c
http://europepmc.org/articles/PMC1241895
http://europepmc.org/articles/PMC1241895