Zobrazeno 1 - 10
of 229
pro vyhledávání: '"John C Magee"'
Autor:
Benjamin L Shneider, Jeff Moore, Nanda Kerkar, John C Magee, Wen Ye, Saul J Karpen, Binita M Kamath, Jean P Molleston, Jorge A Bezerra, Karen F Murray, Kathleen M Loomes, Peter F Whitington, Philip Rosenthal, Robert H Squires, Stephen L Guthery, Ronen Arnon, Kathleen B Schwarz, Yumirle P Turmelle, Averell H Sherker, Ronald J Sokol, Childhood Liver Disease Research Network
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176275 (2017)
INTRODUCTION:Optimizing outcome in biliary atresia (BA) requires timely diagnosis. Cholestasis is a presenting feature of BA, as well as other diagnoses (Non-BA). Identification of clinical features of neonatal cholestasis that would expedite decisio
Externí odkaz:
https://doaj.org/article/cb69c55e6c9c42809f1bb8f09a6520dc
Autor:
Meredith Mealer, John Kittelson, B Taylor Thompson, Arthur P Wheeler, John C Magee, Ronald J Sokol, Marc Moss, Michael G Kahn
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81890 (2013)
OBJECTIVE: Barriers to executing large-scale randomized controlled trials include costs, complexity, and regulatory requirements. We hypothesized that source document verification (SDV) via remote electronic monitoring is feasible. METHODS: Five hosp
Externí odkaz:
https://doaj.org/article/db21c1b5f6b446cab28eee5da67bd6bd
Autor:
Benjamin L. Shneider, Binita M. Kamath, John C. Magee, Nathan P. Goodrich, Kathleen M. Loomes, Wen Ye, Cathie Spino, Estella M. Alonso, Jean P. Molleston, Jorge A. Bezerra, Kasper S. Wang, Saul J. Karpen, Simon P. Horslen, Stephen L. Guthery, Philip Rosenthal, Robert H. Squires, Ronald J. Sokol, for the Childhood Liver Disease Research Network (ChiLDReN)
Publikováno v:
Hepatology Communications, Vol 6, Iss 8, Pp 1910-1921 (2022)
Abstract The conduct of long‐term conventional randomized clinical trials in rare diseases is very difficult, making evidenced‐based drug development problematic. As a result, real‐world data/evidence are being used more frequently to assess ne
Externí odkaz:
https://doaj.org/article/4943757ba56340778b553a64b61dfc1f
Autor:
Benjamin L. Shneider, Catherine A. Spino, Binita M. Kamath, John C. Magee, Rosalinda V. Ignacio, Suiyuan Huang, Simon P. Horslen, Jean P. Molleston, Alexander G. Miethke, Rohit Kohli, Daniel H. Leung, M. Kyle Jensen, Kathleen M. Loomes, Saul J. Karpen, Cara Mack, Philip Rosenthal, Robert H. Squires, Alastair Baker, Sanjay Rajwal, Deirdre Kelly, Ronald J. Sokol, Richard J. Thompson, for ChiLDReN and UK IMAGO/IMAGINE Investigators
Publikováno v:
Hepatology Communications, Vol 6, Iss 8, Pp 1922-1933 (2022)
Abstract There is growing interest in, but limited data about, intestinal bile acid transport inhibitors as treatment for cholestatic liver disease. The current analyses combine two similar randomized placebo‐controlled trials with subsequent exten
Externí odkaz:
https://doaj.org/article/ff927fac8c8f49b3872a5335a74a6819
Autor:
Wen Ye, Daniel H. Leung, Jean P. Molleston, Simon C. Ling, Karen F. Murray, Jennifer L. Nicholas, Suiyuan Huang, Boaz W. Karmazyn, Roger K. Harned, Prakash Masand, Adina L. Alazraki, Oscar M. Navarro, Randolph K. Otto, Joseph J Palermo, Alexander J Towbin, Estella M. Alonso, Wikrom W. Karnsakul, Sarah Jane Schwarzenberg, Glenn F Seidel, Marilyn Siegel, John C. Magee, Michael R. Narkewicz, A. Jay Freeman
Publikováno v:
Hepatology Communications, Vol 5, Iss 8, Pp 1362-1372 (2021)
Methods to identify children with cystic fibrosis (CF) at risk for development of advanced liver disease are lacking. We aim to determine the association between liver stiffness measurement (LSM) by vibration‐controlled transient elastography (VCTE
Externí odkaz:
https://doaj.org/article/1b391aa18d384ad1a5055e9eafc580d3
Autor:
Binita M. Kamath, Cathie Spino, Richard McLain, John C. Magee, Emily M. Fredericks, Kenneth D. Setchell, Alexander Miethke, Jean P. Molleston, Cara L. Mack, Robert H. Squires, Estella M. Alonso, Karen F. Murray, Kathleen M. Loomes, M. Kyle Jensen, Saul J. Karpen, Philip Rosenthal, Danny Thomas, Ronald J. Sokol, Benjamin L. Shneider, for the Childhood Liver Disease Research Network (ChiLDReN)
Publikováno v:
Hepatology Communications, Vol 4, Iss 7, Pp 1012-1018 (2020)
Pruritus is a debilitating symptom for patients with Alagille syndrome (ALGS). In a previously reported trial of maralixibat, an investigational antipruritic agent, itching was assessed using a digital diary based on twice‐daily caregiver observati
Externí odkaz:
https://doaj.org/article/bb0995bcee5c43aa950f9efac0f78e7d
Autor:
Sarah Jane, Schwarzenberg, Joseph J, Palermo, Wen, Ye, Suiyuan, Huang, John C, Magee, Adina, Alazraki, A Jay, Freeman, Roger, Harned, Boaz, Karmazyn, Wikrom, Karnsakul, Daniel H, Leung, Simon C, Ling, Prakash, Masand, Jean P, Molleston, Karen F, Murray, Oscar M, Navarro, Jennifer L, Nicholas, Randolph K, Otto, Shruti M, Paranjape, Marilyn J, Siegel, Janis, Stoll, Alexander J, Towbin, Michael R, Narkewicz, Estella M, Alonso, Averell H, Sherker
Publikováno v:
Journal of pediatric gastroenterology and nutrition. 75(5)
Cystic fibrosis liver disease (CFLD) begins early in life. Symptoms may be vague, mild, or nonexistent. Progressive liver injury may be associated with decrements in patient health before liver disease is clinically apparent. We examined Health-Relat
Autor:
Deirdre Sawinski, Jennifer C. Lai, Sean Pinney, Alice L. Gray, Annette M. Jackson, Darren Stewart, Deborah Jo Levine, Jayme E. Locke, James J. Pomposelli, Matthew G. Hartwig, Shelley A. Hall, Darshana M. Dadhania, Rebecca Cogswell, Richard V. Perez, Jesse D. Schold, Nicole A. Turgeon, Jon Kobashigawa, Jasleen Kukreja, John C. Magee, John Friedewald, John S. Gill, Gabriel Loor, Julie K. Heimbach, Elizabeth C. Verna, Mary Norine Walsh, Norah Terrault, Guiliano Testa, Joshua M. Diamond, Peter P. Reese, Kimberly Brown, Susan Orloff, Maryjane A. Farr, Kim M. Olthoff, Mark Siegler, Nancy Ascher, Sandy Feng, Bruce Kaplan, Elizabeth Pomfret
Publikováno v:
American Journal of Transplantation. 23:316-325
Autor:
Marilyn J Siegel, Daniel H. Leung, Jean P Molleston, Wen Ye, Shruti M Paranjape, A Jay Freeman, Joseph J Palermo, Janis Stoll, Prakash Masand, Boaz Karmazyn, Roger Harned, Simon C Ling, Oscar M Navarro, Wikrom Karnsakul, Adina Alazraki, Sarah Jane Schwarzenberg, Alex J Towbin, Estella M Alonso, Jennifer L. Nicholas, Nicole Green, Randolph K Otto, John C Magee, Michael R Narkewicz
Publikováno v:
Journal of Cystic Fibrosis.
Autor:
Philip J. Rosenthal, Kathleen M. Loomes, Robert H. Squires, Saul J. Karpen, Simon Horslen, John C. Magee, Emily M. Fredericks, Wen Ye, Vicky L. Ng, Ronald J. Sokol, Binita M. Kamath, Kasper S. Wang, Estella M. Alonso, Jean P. Molleston, James E. Heubi, Daniel H. Leung, Kieran Hawthorne, Lisa G. Sorensen
Publikováno v:
Journal of Pediatric Gastroenterology and Nutrition
Objective: To evaluate neurodevelopmental status among children with inherited cholestatic liver diseases with native liver and variables predictive of impairment. Methods: Participants with Alagille syndrome (ALGS), progressive familial intrahepatic