Zobrazeno 1 - 10
of 90
pro vyhledávání: '"John C Gensel"'
Autor:
Timothy J Kopper, John C Gensel
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 3, Pp 508-509 (2021)
Externí odkaz:
https://doaj.org/article/36ae5c22b1854b5088bc263ac2a3678f
Autor:
Ahmed Al-Darraji, Dalia Haydar, Lakshman Chelvarajan, Himi Tripathi, Bryana Levitan, Erhe Gao, Vincent J Venditto, John C Gensel, David J Feola, Ahmed Abdel-Latif
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200474 (2018)
INTRODUCTION:Acute myocardial infarction (MI) is a primary cause of worldwide morbidity and mortality. Macrophages are fundamental components of post-MI inflammation. Pro-inflammatory macrophages can lead to adverse cardiac remodeling and heart failu
Externí odkaz:
https://doaj.org/article/c90316e3724e4f9eaabb110c2c68f31a
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 11, Pp 1895-1896 (2019)
Externí odkaz:
https://doaj.org/article/cacbf486b87c4ce8b19d13f1f3dd94c7
Publikováno v:
eLife, Vol 6 (2017)
How the immune system affects tissue regeneration is not well understood. In this study, we used an emerging mammalian model of epimorphic regeneration, the African spiny mouse, to examine cell-based inflammation and tested the hypothesis that macrop
Externí odkaz:
https://doaj.org/article/bbd57cb6248d4347bc890fabd4d41f09
Autor:
Michael B Orr, John C Gensel
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 10, Pp 1618-1619 (2017)
Externí odkaz:
https://doaj.org/article/acd06dce23ce4b41b09c46f9581087d5
Autor:
Adam R Ferguson, Karen-Amanda Irvine, John C Gensel, Jessica L Nielson, Amity Lin, Johnathan Ly, Mark R Segal, Rajiv R Ratan, Jacqueline C Bresnahan, Michael S Beattie
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59712 (2013)
Spinal cord injury (SCI) and other neurological disorders involve complex biological and functional changes. Well-characterized preclinical models provide a powerful tool for understanding mechanisms of disease; however managing information produced
Externí odkaz:
https://doaj.org/article/9a4b4863850949e6bf582f619bc8828f
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33519 (2012)
Excess glutamate release and associated neurotoxicity contributes to cell death after spinal cord injury (SCI). Indeed, delayed administration of glutamate receptor antagonists after SCI in rodents improves tissue sparing and functional recovery. Des
Externí odkaz:
https://doaj.org/article/2399faf702b44227ac43d94222934d04
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Pre-clinical and clinical spinal cord injury (SCI) studies differ in study design, particularly in the demographic characteristics of the chosen population. In clinical study design, criteria such as such as motor scores, neurological level, and seve
Externí odkaz:
https://doaj.org/article/f597fee39b7b418da8ab251e0ae92682
Autor:
Andrew N. Stewart, John L. Lowe, Ethan P. Glaser, Caitlin A. Mott, Ryan K. Shahidehpour, Katelyn E. McFarlane, William M. Bailey, Bei Zhang, John C. Gensel
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Sex and age are emerging as influential variables that affect spinal cord injury (SCI) recovery. Despite a changing demographic towards older age at the time of SCI, the effects of sex or age on inflammation remain to be elucidate
Externí odkaz:
https://doaj.org/article/2061aa368fc84a18a53d8dff73cebcc9
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Spinal cord injury (SCI) produces chronic, pro-inflammatory macrophage activation that impairs recovery. The mechanisms driving this chronic inflammation are not well understood. Here, we detail the effects of myelin debris on macrophage phy
Externí odkaz:
https://doaj.org/article/bcfad03edf464c22889b0e20e459344f