Zobrazeno 1 - 10
of 731
pro vyhledávání: '"John C Flickinger"'
Autor:
Tingting Zhan, Scott A Waldman, Adam E Snook, Robert Carlson, Jagmohan Singh, Joshua Barton, Babar Bashir, John C Flickinger Jr, Elinor Leong, Trevor R Baybutt, Ellen Caparosa, Amanda Pattison, Jeffrey A Rappaport, Jamin Roh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Adenovirus serotype 5 (Ad5) is a commonly used viral vector for transient delivery of transgenes, primarily for vaccination against pathogen and tumor antigens. However, endemic infections with Ad5 produce virus-specific neutralizing antib
Externí odkaz:
https://doaj.org/article/778fecf5bd054b70893034936a59a9c3
Autor:
John C. Flickinger, Ross E. Staudt, Jagmohan Singh, Robert D. Carlson, Joshua R. Barton, Trevor R. Baybutt, Jeffrey A. Rappaport, Alicja Zalewski, Amanda Pattison, Scott A. Waldman, Adam E. Snook
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Strategies to augment immunity to self/neoantigens expressed by cancers are urgently needed to expand the proportion of patients benefiting from immunotherapy, particularly for GI cancers where only a fraction of patients respond to immunoth
Externí odkaz:
https://doaj.org/article/e22b2a072d4641808bb7b166089c9d83
Autor:
John C. Flickinger, Jagmohan Singh, Yanki Yarman, Robert D. Carlson, Joshua R. Barton, Scott A. Waldman, Adam E. Snook
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The Gram-positive bacterium Listeria monocytogenes (Lm) is an emerging platform for cancer immunotherapy. To date, over 30 clinical trials have been initiated testing Lm cancer vaccines across a wide variety of cancers, including lung, cervical, colo
Externí odkaz:
https://doaj.org/article/f09e4fa5e7f24752a72ae498fa1d7fac
Autor:
Adam E. Snook, Trevor R. Baybutt, Bo Xiang, Tara S. Abraham, John C. Flickinger, Terry Hyslop, Tingting Zhan, Walter K. Kraft, Takami Sato, Scott A. Waldman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background The colorectal cancer antigen GUCY2C exhibits unique split tolerance, evoking antigen-specific CD8+, but not CD4+, T-cell responses that deliver anti-tumor immunity without autoimmunity in mice. Here, the cancer vaccine Ad5-GUCY2C
Externí odkaz:
https://doaj.org/article/bdce3f30665a4a5db1e1ac2e6e6cfd89
Autor:
John M. Varlotto, Isabel Emmerick, Rick Voland, Malcom M. DeCamp, John C. Flickinger, Debra J. Maddox, Christine Herbert, Molly Griffin, Paul Rava, Thomas J. Fitzgerald, Paulo Oliveira, Jennifer Baima, Rahul Sood, William Walsh, Lacey J. McIntosh, Feiran Lou, Mark Maxfield, Negar Rassaei, Karl Uy
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Purpose: To identify the incidence, preoperative risk factors, and prognosis associated with pathologically positive lymph node (pN+) in patients undergoing a sub-lobar resection (SLR).Methods: This is a retrospective study using the National Cancer
Externí odkaz:
https://doaj.org/article/6b38bb933d0947619127470cbce1a34c
Autor:
Johannes Roesch, John B.C. Cho, Daniel K. Fahim, Peter C. Gerszten, John C. Flickinger, Inga S. Grills, Maha Jawad, Ronald Kersh, Daniel Letourneau, Frederick Mantel, Arjun Sahgal, John H. Shin, Brian Winey, Matthias Guckenberger
Publikováno v:
Radiation Oncology, Vol 12, Iss 1, Pp 1-8 (2017)
Abstract Object Stereotactic body radiotherapy (SBRT) for vertebral metastases has emerged as a promising technique, offering high rates of symptom relief and local control combined with low risk of toxicity. Nonetheless, local failure or vertebral i
Externí odkaz:
https://doaj.org/article/097292746fa94d87a29c06df5ced7ae4
Autor:
Adam E. Snook, Scott A. Waldman, Adam R. Hersperger, Priyanka Prajapati, Glen P. Marszalowicz, Natalie A. Ridge, John C. Flickinger, Trevor R. Baybutt, Tara S. Abraham, Michael S. Magee
Figure S11 shows that hGUCY2C-specific 5F9.m28BBz CAR-T cells do not recognize murine GUCY2C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c5b99dc4205587ea934681006c7eb7
https://doi.org/10.1158/2326-6066.22536559.v1
https://doi.org/10.1158/2326-6066.22536559.v1
Publikováno v:
Toxins, Vol 12, Iss 4, p 241 (2020)
The ability of the immune system to precisely target and eliminate aberrant or infected cells has long been studied in the field of infectious diseases. Attempts to define and exploit these potent immunological processes in the fight against cancer h
Externí odkaz:
https://doaj.org/article/ca9a431b081a4df09aa6fd1eaa4a7462
Autor:
John M. Varlotto, Kerri McKie, Rickie P. Voland, John C. Flickinger, Malcolm M. DeCamp, Debra Maddox, Paul Stephen Rava, Thomas J. Fitzgerald, William Walsh, Paulo Oliveira, Negar Rassaei, Jennifer Baima, Karl Uy
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
BackgroundLittle is understood regarding the inter-relation between economic, marital, and racial/ethnic differences in presentation and survival of surgically resected lung cancer patients. Our investigation will assess these differences in addition
Externí odkaz:
https://doaj.org/article/14c4665e0ea14c98bce20447d3265c7c
Autor:
Deborah T. Blumenthal, Robin Buerki, Mitchell Machtay, Valerie Panet-Raymond, Stephanie L. Pugh, Nirav Patil, Eashwar Somasundaram, James R. Connor, Andrew E. Sloan, H. Ian Robins, Grant K. Hunter, Marta Penas-Prado, Justin D. Lathia, Serah Choi, Kristin A Waite, John C. Flickinger, Lynn S. Ashby, Maria Werner-Wasik, Joshua B. Rubin, Michael E. Berens, Merideth M Wendland, Mark R. Gilbert, Jill S. Barnholtz-Sloan, Minesh P. Mehta
Publikováno v:
Journal of Neuro-Oncology
Background/purpose Glioblastoma (GBM) is the most common primary malignant brain tumor. Sex has been shown to be an important prognostic factor for GBM. The purpose of this study was to develop and independently validate sex-specific nomograms for es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1214f53bf74a285d0e66449367b249
http://europepmc.org/articles/PMC8651582
http://europepmc.org/articles/PMC8651582