Zobrazeno 1 - 10
of 93
pro vyhledávání: '"John Broad"'
Autor:
John Broad, Nobuyuki Takahashi, Masaomi Tajimi, Masaki Sudo, Adam Góralczyk, Umesh Parampalli, Kesava Mannur, Toshinori Yamamoto, Gareth J. Sanger
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 60-65 (2016)
The aim was to characterise RQ-00201894, a novel non-macrolide motilin agonist, using human recombinant receptors and then investigate its ability to facilitate cholinergic activity in human stomach. A reporter gene assay assessed motilin receptor fu
Externí odkaz:
https://doaj.org/article/f635d8a8c56549dfabfbcb812b73f3c9
Autor:
John Broad
Publikováno v:
Landless Households in Rural Europe, 1600-1900 ISBN: 9781800106031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5570dd3b89cd4a45f5abf0f34e6cfd26
https://doi.org/10.1017/9781800106031.004
https://doi.org/10.1017/9781800106031.004
Autor:
John Broad
Between 1540 and 1920 the English elite transformed the countryside and landscape by building up landed estates which were concentrated around their country houses. John Broad's study of the Verney family of Middle Claydon in Buckinghamshire demonstr
Autor:
Thomas White, MD, Rafael Justiz, MD, Wilson Almonte, MD, Velimir Micovic, MD, Binit Shah, MD, Eric Anderson, MD, Leonardo Kapural, MD, PhD, Harold Cordner, MD, Amr El-Naggar, MD, Michael Fishman, MD, MBA, Yashar Eshraghi, MD, Philip Kim, MD, Alaa Abd-Elsayed, MD, Krishnan Chakravarthy, Yoann Millet, MD, Mahendra Sanapati, MD, Nathan Harrison, MD, Brandon Goff, DO, Mayank Gupta, MD, Prabhdeep Grewal, MD, Michael Wilkinson, MD, Richard Bundschu, MD, Andrew Will, MD, Pankaj Satija, MD, Sean Li, MD, Scott Dulebohn, MD, John Broadnax, MD, Gennady Gekht, MD, Ken Wu, MD, Steven Falowski, MD, Wesley Park, MPH, David L. Cedeno, PhD, Ricardo Vallejo, MD, PhD
Publikováno v:
North American Spine Society Journal, Vol 19, Iss , Pp 100528- (2024)
ABSTRACT: Background: Successful treatments for intractable chronic low back pain (CLBP) in patients who are not eligible for surgical interventions are scarce. The superior efficacy of differential target multiplexed spinal cord stimulation (DTM SCS
Externí odkaz:
https://doaj.org/article/84ce2aea2ef74d418aa4155633352992
Autor:
Taher Darreh-Shori, Mohamed A. Thaha, Joanne Chin-Aleong, Alexandra Palmer, M. Jill Saffrey, Joanne E. Martin, John Broad, Shezan Elahi, Shafi Ahmed, Victor W S Kung, Charles H. Knowles, Gareth J. Sanger, Azadeh Karami, Rebecca Carroll
Publikováno v:
Gut
ObjectiveTo determine if human colonic neuromuscular functions decline with increasing age.DesignLooking for non-specific changes in neuromuscular function, a standard burst of electrical field stimulation (EFS) was used to evoke neuronally mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5119efb950b54f1020a36ded87bcc30
Autor:
Toshinori Yamamoto, Kesava R. Mannur, Nobuyuki Takahashi, Masaomi Tajimi, Masaki Sudo, Gareth J. Sanger, Adam Góralczyk, Umesh Parampalli, John Broad
Publikováno v:
Journal of Pharmacological Sciences, Vol 130, Iss 2, Pp 60-65 (2016)
The aim was to characterise RQ-00201894, a novel non-macrolide motilin agonist, using human recombinant receptors and then investigate its ability to facilitate cholinergic activity in human stomach. A reporter gene assay assessed motilin receptor fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c771db32d375f3fbba5f8ad65ba18a26
http://www.sciencedirect.com/science/article/pii/S1347861315002261
http://www.sciencedirect.com/science/article/pii/S1347861315002261
Publikováno v:
European Journal of Pharmacology. 752:34-39
Ulimorelin (TZP101) is a ghrelin receptor agonist that stimulates intestinal motility, but also reduces blood pressure in rodents and humans and dilates blood vessels. It has been proposed as a treatment for intestinal motility disorders. Here we inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0157f955e94a1bcca80354a78fb03ed1
https://doi.org/10.1016/j.ejphar.2015.02.005
https://doi.org/10.1016/j.ejphar.2015.02.005
Autor:
John Broad
Publikováno v:
Vernacular Architecture. 46:1-7
Over twenty years ago David and Barbara Martin began a debate on the nature and uses of detached kitchens. This article revisits the question but focuses on the archival evidence of two very detailed estate surveys from seventeenth-century Wiltshire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7384d47c83eb58a393b9c1bc7a61932
https://doi.org/10.1080/03055477.2015.1123411
https://doi.org/10.1080/03055477.2015.1123411
Publikováno v:
Neurogastroenterology & Motility. 26:1311-1322
Background Motilin agonists promote human gastric motility and cholinergic activity, but excitatory and inhibitory actions are reported in the esophagus. The effect of 5-HT4 agonists in esophagus is also unclear. Perhaps the use of drugs with additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8907ce19563097f17c4af6945e830af
https://doi.org/10.1111/nmo.12394
https://doi.org/10.1111/nmo.12394
Publikováno v:
Handbook of experimental pharmacology. 239
Ghrelin and motilin are released from gastrointestinal endocrine cells during hunger, to act through G protein-coupled receptors that have closely related amino acid sequences. The actions of ghrelin are more complex than motilin because ghrelin also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f8c6f9a0c8803e32a2c2abd18263d1b
https://pubmed.ncbi.nlm.nih.gov/28035532
https://pubmed.ncbi.nlm.nih.gov/28035532