Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John Bradsher"'
Autor:
Martine Behra, John Bradsher, Rachid Sougrat, Viviana Gallardo, Miguel L Allende, Shawn M Burgess
Publikováno v:
PLoS Genetics, Vol 5, Iss 4, p e1000455 (2009)
In humans, the absence or irreversible loss of hair cells, the sensory mechanoreceptors in the cochlea, accounts for a large majority of acquired and congenital hearing disorders. In the auditory and vestibular neuroepithelia of the inner ear, hair c
Externí odkaz:
https://doaj.org/article/7b684ce6317d4711a155c24fb2a49372
Autor:
Curtis C. Harris, Clare H. McGowan, Veronique Blais, John Bradsher, Nozomu Yanaihara, Steven P. Linke, Qin Yang, Sagar Sengupta, Ran Zhang
Supplementary Figure 3 from BLM Helicase Facilitates Mus81 Endonuclease Activity in Human Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a0475194e3d779b13ad13b2a16bf0b
https://doi.org/10.1158/0008-5472.22365174.v1
https://doi.org/10.1158/0008-5472.22365174.v1
Autor:
Curtis C. Harris, Clare H. McGowan, Veronique Blais, John Bradsher, Nozomu Yanaihara, Steven P. Linke, Qin Yang, Sagar Sengupta, Ran Zhang
Supplementary Figure 2 from BLM Helicase Facilitates Mus81 Endonuclease Activity in Human Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7fcdb9e41f0f0021ca759ef7465975
https://doi.org/10.1158/0008-5472.22365177
https://doi.org/10.1158/0008-5472.22365177
Autor:
Curtis C. Harris, Clare H. McGowan, Veronique Blais, John Bradsher, Nozomu Yanaihara, Steven P. Linke, Qin Yang, Sagar Sengupta, Ran Zhang
Bloom syndrome is a rare, autosomal recessive inherited disorder in humans. The product of the Bloom syndrome mutated gene, designated BLM, is a member of the RecQ helicase family. BLM has been proposed to function at the interface of replication and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a294ed8e4d987e6e5a88be60b4d6408
https://doi.org/10.1158/0008-5472.c.6494568
https://doi.org/10.1158/0008-5472.c.6494568
Autor:
Modupe M. Teniola, Jacek Capala, Lyuba Varticovski, John Bradsher, Ana I. Robles, Mollie H. Wright, Steven S. Feis, Thuy T. Koll, Mekel M. Richardson
Publikováno v:
Molecular Cancer Therapeutics. 7:1985-1992
Inhibition of heat shock protein 90 (HSP90) leads to inappropriate processing of proteins involved in cell survival pathways. We found that HSP90 inhibitor, 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (DMAG), is synergistic with radiation f
Autor:
Qin Yang, Nozomu Yanaihara, Clare H. McGowan, Steven P. Linke, Sagar Sengupta, Veronique Blais, Curtis C. Harris, John Bradsher, Ran Zhang
Publikováno v:
Cancer Research. 65:2526-2531
Bloom syndrome is a rare, autosomal recessive inherited disorder in humans. The product of the Bloom syndrome mutated gene, designated BLM, is a member of the RecQ helicase family. BLM has been proposed to function at the interface of replication and
Autor:
Viviana E Gallardo, Abdel G. Elkahloun, Shawn M. Burgess, Aranza I. Torrado, Lisha Xu, Jennifer Idol, Chie Satou, Shin-ichi Higashijima, Brant M. Weinstein, John Bradsher, Kenna M. Shaw, Martine Behra, Jessica Sheehy, Seth Zonies
Publikováno v:
BMC Developmental Biology
BMC Developmental Biology, Vol 12, Iss 1, p 6 (2012)
BMC Developmental Biology, Vol 12, Iss 1, p 6 (2012)
Background Because of the structural and molecular similarities between the two systems, the lateral line, a fish and amphibian specific sensory organ, has been widely used in zebrafish as a model to study the development/biology of neuroepithelia of
Autor:
John Bradsher, Shawn M. Burgess, Rachid Sougrat, Martine Behra, Miguel L. Allende, Viviana E Gallardo
Publikováno v:
PLOS GENETICS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
PLoS Genetics, Vol 5, Iss 4, p e1000455 (2009)
PLoS Genetics
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
PLoS Genetics, Vol 5, Iss 4, p e1000455 (2009)
PLoS Genetics
In humans, the absence or irreversible loss of hair cells, the sensory mechanoreceptors in the cochlea, accounts for a large majority of acquired and congenital hearing disorders. In the auditory and vestibular neuroepithelia of the inner ear, hair c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1db5e8ab17bc6b39181799947916e8c
Autor:
Luca Proietti De Santis, Jérôme Auriol, John Bradsher, Ingrid Grummt, Jean-Marc Egly, Sebastian Iben, Jean Luc Vonesch
Publikováno v:
Molecular cell. 10(4)
Mutation in the CSB gene results in the human Cockayne's syndrome (CS). Here, we provide evidence that CSB is found not only in the nucleoplasm but also in the nucleolus within a complex (CSB IP/150) that contains RNA pol I, TFIIH, and XPG and promot
Publikováno v:
The Journal of biological chemistry. 275(43)
In order to unravel the mechanism that regulates transcription of protein-coding genes, we investigated the function of the p44 subunit of TFIIH, a basal transcription factor that is also involved in DNA repair. We have shown previously that mutation