Výsledky vyhledávání - "John Binuclara"

Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma

Autor: Chandrasekar Naveenkumar, Thiruvengadam Devaki, John Binuclara, Arumugam Paramasivam, Selvam Senthilraja, Subramanian Raghunandhakumar, Pandi Anandakumar, Selvamani Asokkumar, Sundaram Jagan

Publikováno v: Toxicology Letters. 223:60-72

Dysregulated cell proliferation and tumorigenesis is frequently encountered in several cancers including hepatocellular carcinogenesis (HCC). Thus, agents that inhibit cell proliferation and restrain hepatic tumorigenesis through cell cycle regulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45544521b3a4f9a1f4863e457b7177b9
https://doi.org/10.1016/j.toxlet.2013.08.018

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Baicalein improves antioxidant status and membrane-bound enzymes during oxidative stress in benzo(a)pyrene-induced lung carcinogenesis in mice

Autor: John Binuclara, Chandrashekar Naveenkumar, Thiruvengadam Devaki, Subramanian Raghunandhakumar, Selvamani Asokkumar

Publikováno v: Biomedicine & Preventive Nutrition. 2:138-144

The chemopreventive efficacy of baicalein (BE) flavanoid during benzo(a)pyrene [B(a)P]-induced lung carcinogenesis was investigated in Swiss albino mice. Lung cancer was induced by 50 mg/kg body weight of B(a)P, given orally twice a week for 4 succes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f124f5759d0e16a66903fd962ab95945
https://doi.org/10.1016/j.bionut.2011.12.004

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Mitigating role of baicalein on lysosomal enzymes and xenobiotic metabolizing enzyme status during lung carcinogenesis of Swiss albino mice induced by benzo(a)pyrene

Autor: Chandrashekar Naveenkumar, Thandavamoorthy Premkumar, John Binuclara, Balan Rajan, Subramanian Raghunandakumar, Thiruvengadam Devaki, Selvamani Asokkumar

Publikováno v: Fundamentalclinical pharmacology. 28(3)

The lungs mainly serve as a primary site for xenobiotic metabolism and constitute an important defense mechanism against inhalation of carcinogens. Our current study aimed to evaluate the chemotherapeutic efficacy of baicalein (BE) in Swiss albino mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed405f6bed60b1c18585585541c0f6f
https://pubmed.ncbi.nlm.nih.gov/23834621

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