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pro vyhledávání: '"John Besemer"'
Autor:
John Besemer, Mark Borodovsky
Publikováno v:
Nucleic Acids Research
The task of gene identification frequently confronting researchers working with both novel and well studied genomes can be conveniently and reliably solved with the help of the GeneMark web software (http://opal.biology.gatech.edu/GeneMark/). The web
Autor:
Angela G. King, Sorel Fitz-Gibbon, Malgorzata M. Slupska, John Besemer, Jeffrey H Miller, Mark Borodovsky
Publikováno v:
Journal of Molecular Biology. 309:347-360
We mapped transcription start sites for ten unrelated protein-encoding Pyrobaculum aerophilum genes by primer extension and S 1 nuclease mapping. All of the mapped transcripts start at the computationally predicted translation start codons, two of wh
Publikováno v:
Nucleic acids research. 29(12)
Improving the accuracy of prediction of gene starts is one of a few remaining open problems in computer prediction of prokaryotic genes. Its difficulty is caused by the absence of relatively strong sequence patterns identifying true translation initi
Autor:
Mark Borodovsky, Ambrose Jong, John Besemer, Yu Hua Chen, Sheng-He Huang, Guoying Kong, Steven Chen
Publikováno v:
Functionalintegrative genomics. 1(5)
The IbeA (ibe10) gene is an invasion determinant contributing to E. coli K1 invasion of the blood-brain barrier. This gene has been cloned and characterized from the chromosome of an invasive cerebrospinal fluid isolate of E. coli K1, strain RS218 (0
Autor:
Mark Borodovsky, John Besemer
Publikováno v:
Nucleic acids research. 27(19)
Computer methods of accurate gene finding in DNA sequences require models of protein coding and non-coding regions derived either from experimentally validated training sets or from large amounts of anonymous DNA sequence. Here we propose a new, heur
Publikováno v:
Current Protocols in Bioinformatics
In this unit, the GeneMark and GeneMark.hmm programs are presented as two different methods for the in silico prediction of genes in prokaryotes. GeneMark can be used for whole genome analysis as well as for the local analysis of a particular gene an