Zobrazeno 1 - 10
of 53
pro vyhledávání: '"John B.E. Burch"'
Autor:
Maurice J.B. van den Hoff, Aimee L. Phelps, Marie M. Lockhart, Andy Wessels, Russell A. Norris, Richard F. Adamo, Robert W. Dettman, Bram van Wijk, Laura E. Briggs, José M. Pérez-Pomares, Kimberly Sauls, John B.E. Burch
Publikováno v:
Developmental biology, 366(2), 111-124. Academic Press Inc.
The importance of the epicardium for myocardial and valvuloseptal development has been well established; perturbation of epicardial development results in cardiac abnormalities, including thinning of the ventricular myocardial wall and malformations
Autor:
Delphine Champeval, Kenneth S. Zaret, Elena Caretti, Amelie Calmont, John B.E. Burch, Maria Rosaria Bassi, Alfonso Bellacosa, Salvatore Cortellino, Michal Jarnik, Baolin Wang, Lionel Larue, Chengbing Wang
Publikováno v:
Developmental Biology. 325:225-237
Primary cilia are assembled and maintained by evolutionarily conserved intraflagellar transport (IFT) proteins that are involved in the coordinated movement of macromolecular cargo from the basal body to the cilium tip and back. The IFT machinery is
Autor:
Andrew Lindsley, Paige Snider, Anthony B. Firulli, Rhonda Rogers, Jian Wang, Brenda Lilly, Simon J. Conway, Hong-Ming Zhou, John B.E. Burch, Shrinagesh V. Koushik, Agnieszka Kruzynska-Frejtag, Michael A. Olaopa
Publikováno v:
Developmental Biology. 307(2):340-355
Periostin is a fasciclin-containing adhesive glycoprotein that facilitates the migration and differentiation of cells that have undergone epithelial–mesenchymal transformation during embryogenesis and in pathological conditions. Despite the importa
Publikováno v:
STEM CELLS. 24:1236-1245
Since rates of cardiomyocyte generation in the embryo are much higher than within the adult, we explored whether the embryonic heart would serve as useful experimental system for examining the myocardial potential of adult stem cells. Previously, we
Autor:
Esther Merki, Angel Raya, Monica Zamora, Juan Carlos Izpisua Belmonte, John B.E. Burch, Steven W. Kubalak, Pilar Ruiz-Lozano, Perla Kaliman, Kenneth R. Chien, Xiaoxue Zhang, Yasuhiko Kawakami, Jianming Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 102:18455-18460
Vitamin A signals play critical roles during embryonic development. In particular, heart morphogenesis depends on vitamin A signals mediated by the retinoid X receptor α (RXRα), as the systemic mutation of this receptor results in thinning of the m
Autor:
John B.E. Burch
Publikováno v:
Seminars in Cell & Developmental Biology. 16:71-81
GATA factors regulate critical events in hematopoietic lineages (GATA-1/2/3), the heart and gut (GATA-4/5/6) and various other tissues. Transgenic approaches have revealed that GATA genes are regulated in a modular fashion by sets of enhancers that g
Publikováno v:
The Anatomical Record. :1062-1071
The cGATA-6 gene is flanked by an enhancer that selectively marks the atrioventricular conduction system (AVCS) in transgenic mice. This enhancer reads anterior/posterior and medial/lateral positional information very early in the cardiogenic program
Autor:
Dorene L. Davis, Aimee L. Phelps, Andy Wessels, John B.E. Burch, Amy L. Juraszek, Angela V. Edwards
Publikováno v:
Mechanisms of Development. 108:105-119
The transcriptional programs that specify the distinct components of the cardiac conduction system are poorly understood, in part due to a paucity of definitive molecular markers. In the present study we show that a cGATA-6 gene enhancer can be used
Publikováno v:
NIH guide for grants and contracts
The evolutionarily conserved GATA-5 transcription factor is an early and persistent marker of heart and gut development in diverse vertebrate species. To search for control regions that might regulate the chicken GATA-5 (cGATA-5) gene, we assayed a s
Publikováno v:
Developmental Genetics. 22:263-277
The GATA-4/5/6 genes encode transcription factors implicated previously in the regula- tion of cardiac-specific differentiation programs. How- ever, recent analyses of mouse GATA-4 null mutations found evidence for function in endoderm development (i