Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John B. Rudell"'
Autor:
Francesca Boscolo Sesillo, Varsha Rajesh, Michelle Wong, Pamela Duran, John B. Rudell, Courtney P. Rundio, Brittni B. Baynes, Louise C. Laurent, Alessandra Sacco, Karen L. Christman, Marianna Alperin
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Pelvic floor muscle (PFM) injury during childbirth is a key risk factor for pelvic floor disorders that affect millions of women worldwide. Muscle stem cells (MuSCs), supported by the fibro-adipogenic progenitors (FAPs) and immune cells, are
Externí odkaz:
https://doaj.org/article/86125534191e496297718193c6076989
Publikováno v:
Hum Mol Genet
Human molecular genetics, vol 28, iss 16
Human molecular genetics, vol 28, iss 16
Agrin is a large extracellular matrix protein whose isoforms differ in their tissue distribution and function. Motoneuron-derived y+z+ agrin regulates the formation of the neuromuscular junction (NMJ), while y−z− agrin is widely expressed and has
Autor:
Dorothy W. Gietzen, John B. Rudell, John A. Payne, Irène Baccelli, Catherine Ross-Inta, James W. Sharp
Publikováno v:
Journal of neurochemistry, vol 127, iss 4
The anterior piriform cortex (APC) is activated by, and is the brain area most sensitive to, essential (indispensable) amino acid (IAA) deficiency. The APC is required for the rapid (20 min) behavioral rejection of IAA deficient diets and increased f
Autor:
John B. Rudell, Michael J. Ferns
Publikováno v:
Developmental Neurobiology. 73:399-410
At the neuromuscular junction (NMJ), the postsynaptic localization of muscle acetylcholine receptor (AChR) is regulated by neural signals and occurs via several processes including metabolic stabilization of the receptor. However, the molecular mecha
Publikováno v:
Neuroscience. 163:222-232
At the developing vertebrate neuromuscular junction, the acetylcholine receptor becomes aggregated at high density in the postsynaptic muscle membrane. Receptor localization is regulated by the motoneuron-derived factor, agrin, and requires an intrac
Autor:
Young I. Lee, Sergey Yechikhov, Steven J. Burden, Lucia S. Borges, Matthew B. Friese, John B. Rudell, Michael J. Ferns
Publikováno v:
The Journal of Neuroscience. 28:11468-11476
At the neuromuscular junction, the acetylcholine receptor (AChR) is specifically clustered in the postsynaptic membrane via interactions with rapsyn and other scaffolding proteins. However, it remains unclear where these proteins bind on the AChR and
Publikováno v:
The Journal of Comparative Neurology. 494:485-494
The anterior piriform cortex (APC) has been shown to be an essential brain structure for the detection of dietary indispensable amino acid (IAA) deficiency, but little has been known about possible molecular detection mechanisms. Increased phosphoryl
Publikováno v:
The Journal of biological chemistry, vol 289, iss 1
The molecular determinants that govern nicotinic acetylcholine receptor (AChR) assembly and trafficking are poorly defined, and those identified operate largely during initial receptor biogenesis in the endoplasmic reticulum. To identify determinants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5a5acb40462583c30b13d451f1af85
https://escholarship.org/uc/item/14r4n2g9
https://escholarship.org/uc/item/14r4n2g9
Autor:
John B, Rudell, Michael J, Ferns
Publikováno v:
Developmental neurobiology. 73(5)
At the neuromuscular junction (NMJ), the postsynaptic localization of muscle acetylcholine receptor (AChR) is regulated by neural signals and occurs via several processes including metabolic stabilization of the receptor. However, the molecular mecha
Autor:
Adam J Rechs, Dorothy W. Gietzen, Catherine Ross-Inta, Shuzhen Hao, John B. Rudell, Todd J Kelman
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(5)
Protein synthesis requires a continuous supply of all of the indispensable (essential) amino acids (IAAs). If any IAA is deficient, animals must obtain the limiting amino acid by diet selection. Sensing of IAA deficiency requires an intact anterior p