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pro vyhledávání: '"John B. Little"'
Supplementary Figure S2 from Cellular Mechanisms for Low-Dose Ionizing Radiation–Induced Perturbation of the Breast Tissue Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02122a6d5ee6a28e07e91355654d4719
https://doi.org/10.1158/0008-5472.22363404
https://doi.org/10.1158/0008-5472.22363404
Radiation exposure is an important form of environmental carcinogen and has been associated with increased risk of breast cancer. Epigenetic events, especially those involving alterations in the breast stromal microenvironment, may play an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746584aa68a5b451143e8cf31ce0100b
https://doi.org/10.1158/0008-5472.c.6493698.v1
https://doi.org/10.1158/0008-5472.c.6493698.v1
Supplementary Figure Legends from Cellular Mechanisms for Low-Dose Ionizing Radiation–Induced Perturbation of the Breast Tissue Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36208d1d208ef4187d636c611666e546
https://doi.org/10.1158/0008-5472.22363410.v1
https://doi.org/10.1158/0008-5472.22363410.v1
Publikováno v:
Translational Cancer Research
Via regulation of cellular stress responses, p53 contributes to the maintenance of homeostasis. Contrary to its well-established pro-death function, p53 is also implicated in promoting cell survival by mediating the adaptive stress response. Emerging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b955d5a6243fa368a91b5c580600c80
https://doi.org/10.21037/tcr.2019.12.89
https://doi.org/10.21037/tcr.2019.12.89
Autor:
John B. Little
Publikováno v:
Bulletin of the American Mathematical Society. 57:515-521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cbe280ae208a3ce329d0103382ae8c2
https://doi.org/10.1090/bull/1690
https://doi.org/10.1090/bull/1690
Autor:
Yu-Fen Lin, Hatsumi Nagasawa, John B Little, Takamitsu A Kato, Hung-Ying Shih, Xian-Jin Xie, Paul F Wilson, John R Brogan, Akihiro Kurimasa, David J Chen, Joel S Bedford, Benjamin P C Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93579 (2014)
We have examined cell-cycle dependence of chromosomal aberration induction and cell killing after high or low dose-rate γ irradiation in cells bearing DNA-PKcs mutations in the S2056 cluster, the T2609 cluster, or the kinase domain. We also compared
Externí odkaz:
https://doaj.org/article/c5e76ff023f84fe181a3f8854d96a82b
Autor:
John B. Little
Publikováno v:
Current trends in radiation protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69befc135d959f4f48480e7f9d272847
https://doi.org/10.1051/978-2-7598-0117-6.c004
https://doi.org/10.1051/978-2-7598-0117-6.c004
Publikováno v:
Journal of Molecular Cell Biology
A role of tumor-suppressive activity of p53 in the tumor microenvironment (TME) has been implicated but remains fairly understudied. To address this knowledge gap, we leveraged our MdmxS314A mice as recipients to investigate how implanted tumor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f0510fb64da5947119cb790a11df45
https://pubmed.ncbi.nlm.nih.gov/32706867
https://pubmed.ncbi.nlm.nih.gov/32706867
Publikováno v:
Journal of Molecular Cell Biology. 9:154-165
Deregulation of the tyrosine kinase signalling is often associated with tumour progression and drug resistance, but its underlying mechanisms are only partly understood. In this study, we investigated the effects of the receptor tyrosine kinase AXL o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a170ae424ec393edeb848bc36ad953b5
https://doi.org/10.1093/jmcb/mjw045
https://doi.org/10.1093/jmcb/mjw045
Autor:
John B. Little, Anna de Polo, Xue-Song Liu, Casimiro Gerarduzzi, Manale El Kharbili, Zhi-Min Yuan
Publikováno v:
Journal of Biological Chemistry. 291:25937-25949
Deregulated receptor tyrosine kinase (RTK) signaling is frequently associated with tumorigenesis and therapy resistance, but its underlying mechanisms still need to be elucidated. In this study, we have shown that the RTK human epidermal growth facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95b012bc92678f2060461607ed46bb0c
https://doi.org/10.1074/jbc.m116.752303
https://doi.org/10.1074/jbc.m116.752303