Zobrazeno 1 - 10
of 629
pro vyhledávání: '"John B. Furness"'
Autor:
Pedro Trevizan-Baú, Mitchell Ty Ringuet, Martin J. Stebbing, Robin M. McAllen, John B. Furness, Scott N. Mueller
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103036- (2024)
Summary: Neurons that originate from pre-vertebral sympathetic ganglia, the splanchnic-celiac-superior mesenteric ganglion complex (SCSMG) in mouse, have important roles in control of organs of the upper abdomen. Here, we present a protocol for the i
Externí odkaz:
https://doaj.org/article/4c0a3fddbeca41ad848639451d5b9888
Autor:
Jichao Ma, Duyen Nguyen, Jazune Madas, Andrew M. Kwiat, Zulema Toledo, Ariege Bizanti, Nicole Kogut, Anas Mistareehi, Kohlton Bendowski, Yuanyuan Zhang, Jin Chen, De-Pei Li, Terry L. Powley, John B. Furness, Zixi Cheng
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract The dorsal root ganglia (DRG) project spinal afferent axons to the stomach. However, the distribution and morphology of spinal afferent axons in the stomach have not been well characterized. In this study, we used a combination of state-of-t
Externí odkaz:
https://doaj.org/article/b51f0dd42a984225b7ffa9454b6bbc5c
Autor:
John B. Furness, Enie Lei, Billie Hunne, Cameron D. Adams, Alan J. Burns, Jill Wykosky, Therese E. Fazio Coles, Linda J. Fothergill, Juan C. Molero, Ruslan V. Pustovit, Lincon A. Stamp
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/55ac24c3524e4630becd2935e6965f80
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 11, Pp 953-966 (2021)
Abstract The gut immune system in the healthy intestine is anti‐inflammatory, but can move to a pro‐inflammatory state when the gut is challenged by pathogens or in disease. The nervous system influences the level of inflammation through enteric
Externí odkaz:
https://doaj.org/article/9c12980ac91f4045a051574a2429e2cb
Autor:
Rachel M. McQuade, Lewis M. Singleton, Hongyi Wu, Sophie Lee, Remy Constable, Madeleine Di Natale, Mitchell T. Ringuet, Joel P. Berger, Jessica Kauhausen, Clare L. Parish, David I. Finkelstein, John B. Furness, Shanti Diwakarla
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Parkinson’s disease (PD) is associated with neuronal damage in the brain and gut. This work compares changes in the enteric nervous system (ENS) of commonly used mouse models of PD that exhibit central neuropathy and a gut phenotype. Enter
Externí odkaz:
https://doaj.org/article/84b393003cc04c729aedad1290f826e6
Autor:
Sophie C. Payne, Jack Alexandrovics, Ross Thomas, Robert K. Shepherd, John B. Furness, James B. Fallon
Publikováno v:
Royal Society Open Science, Vol 7, Iss 2 (2020)
Ulcerative colitis is a chronic disease in which the mucosa of the colon or rectum becomes inflamed. An objective biomarker of inflammation will provide quantitative measures to support qualitative assessment during an endoscopic examination. Previou
Externí odkaz:
https://doaj.org/article/1057ce5e03b64c5e82932dd0d3aec315
Autor:
Sophie C. Payne, John B. Furness, Owen Burns, Alicia Sedo, Tomoko Hyakumura, Robert K. Shepherd, James B. Fallon
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Electrical stimulation of the cervical vagus nerve is an emerging treatment for inflammatory bowel disease (IBD). However, side effects from cervical vagal nerve stimulation (VNS) are often reported by patients. Here we hypothesized that stimulating
Externí odkaz:
https://doaj.org/article/fe6c99f407dc4d40b3faf2ffd3fb3a7c
Publikováno v:
Nutrients, Vol 13, Iss 4, p 1073 (2021)
Dietary organic selenium (Se) is commonly utilized to increase formation of selenoproteins, including the major antioxidant protein, glutathione peroxidase (GPx). Inorganic Se salts, such as sodium selenite, are also incorporated into selenoproteins,
Externí odkaz:
https://doaj.org/article/5a19637846774cfdb00bead05cd55099
Autor:
Jeremy J. Cottrell, John B. Furness, Udani A. Wijesiriwardana, Mitchell Ringuet, Fan Liu, Kristy DiGiacomo, Brian J. Leury, Iain J. Clarke, Frank R. Dunshea
Publikováno v:
Animals, Vol 10, Iss 4, p 690 (2020)
With increases in the frequency, intensity and duration of heat waves forecast plus expansion of tropical agriculture, heat stress (HS) is both a current and an emerging problem. As cinnamon has been shown to increase insulin sensitivity, which is pa
Externí odkaz:
https://doaj.org/article/e1b9e91e0b3e4614b905b4bba5428d2d
Publikováno v:
Royal Society Open Science, Vol 5, Iss 3 (2018)
Inflammatory damage to the bowel, as occurs in inflammatory bowel disease (IBD), is debilitating to patients. In both patients and animal experimental models, histological analyses of biopsies and endoscopic examinations are used to evaluate the dise
Externí odkaz:
https://doaj.org/article/4c40e824a4c148be89d4a5958ac2e669