Zobrazeno 1 - 10
of 45
pro vyhledávání: '"John B. Ancsin"'
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 10, Pp 2091-2101 (2005)
Macrophages (Mϕ) at sites of acute tissue injury accumulate and export cholesterol quickly. This metabolic activity is likely dependent on the physiological function of a major acute-phase protein, serum amyloid A 2.1 (SAA2.1), that is synthesized b
Externí odkaz:
https://doaj.org/article/36cf904626364ad0ab4d8c1fecc42cc7
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3867 (2008)
During episodes of acute-inflammation high-density lipoproteins (HDL), the carrier of so-called good cholesterol, experiences a major change in apolipoprotein composition and becomes acute-phase HDL (AP-HDL). This altered, but physiologically importa
Externí odkaz:
https://doaj.org/article/8b155357dd43460dbe71ae22987e51e1
Autor:
Erik Lundgren, Per Westermark, Robert Kisilevsky, Ana M. Damas, John B. Ancsin, Erik Hermansson, Fredrik Noborn, Jan Johansson, Jin-Ping Li, Ingrid Dacklin, Xiao Zhang, Paul O'Callaghan, Jenny Presto, Maria João Saraiva
Publikováno v:
Proceedings of the National Academy of Sciences. 108:5584-5589
Transthyretin (TTR) is a homotetrameric protein that transports thyroxine and retinol. Tetramer destabilization and misfolding of the released monomers result in TTR aggregation, leading to its deposition as amyloid primarily in the heart and periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75afea667991d7acdd17bc6943605ed2
https://doi.org/10.1073/pnas.1101194108
https://doi.org/10.1073/pnas.1101194108
Publikováno v:
Amyloid. 14:21-32
Amyloid formation in vivo is a much more complicated process than studies of in vitro protein/peptide fibrillogenesis would lead one to believe. Amyloidogenesis in vivo involves multiple components, some no less important than the amyloidogenic prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88577620cc73daa1f83e7f9996a8c4cf
https://doi.org/10.1080/13506120601116419
https://doi.org/10.1080/13506120601116419
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Serum amyloid A (SAA) is an acute-phase protein that circulates bound to high density lipoprotein (HDL) and can influence HDL function as part of a poorly understood defense re-sponse to tissue trauma or infection. We have previously demonstrated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::491d057869b0ca2480f57a4f05c0d31c
https://doi.org/10.1161/atvb.35.suppl_1.110
https://doi.org/10.1161/atvb.35.suppl_1.110
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
The impaired clearance of plasma triglycerides is a major cause of clinical hypertriglyceridemia, a condition which affects about one third of adults in the G7 countries and is a risk factor for a number of diseases, including cardiovascular disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36b3c2bdce2a813dd2c28bb7ddb4271c
https://doi.org/10.1161/atvb.35.suppl_1.537
https://doi.org/10.1161/atvb.35.suppl_1.537
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 10, Pp 2091-2101 (2005)
Macrophages (Mphi) at sites of acute tissue injury accumulate and export cholesterol quickly. This metabolic activity is likely dependent on the physiological function of a major acute-phase protein, serum amyloid A 2.1 (SAA2.1), that is synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d35f4260520146a78964ca985c34448
https://doi.org/10.1194/jlr.m500191-jlr200
https://doi.org/10.1194/jlr.m500191-jlr200
Autor:
Robert Kisilevsky, Walter A. Szarek, Elena Elimova, Ali Berkin, Sandra Marone, Shridhar Bhat, John B. Ancsin
Publikováno v:
The American Journal of Pathology. 164:2127-2137
Two novel sugars, 2-acetamido-1,3,6-tri-O-acetyl-2,4-dideoxy-α- and β-d-xylo-hexopyranoses, have been synthesized and their effects on heparan sulfate biosynthesis using primary mouse hepatocytes in tissue culture have been assessed. At concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a9f3a45c61114c716ed44b41073969b
https://doi.org/10.1016/s0002-9440(10)63771-6
https://doi.org/10.1016/s0002-9440(10)63771-6
Autor:
Robert Kisilevsky, John B. Ancsin
Publikováno v:
Journal of Biological Chemistry. 279:21824-21832
Circumsporozoite protein (CSP) coats the malarial sporozoite and functions to target the liver for infection, which is the first step to developing malaria. An important tissue ligand for CSP is the glycosaminoglycan heparan sulfate (HS) found on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c6529fbcf0d886c8809b6dfc4a99bd7
https://doi.org/10.1074/jbc.m401979200
https://doi.org/10.1074/jbc.m401979200
Autor:
Sandra Marone, Walter A. Szarek, Rahul Vohra, John B. Ancsin, Robert Kisilevsky, Zhanjiang Li
Publikováno v:
Journal of Molecular Neuroscience. 24:167-172
In vivo amyloids consist of two classes of constituents. The first is the disease-defining protein, β-amyloid (Aβ), in Alzheimer’s disease. The second is a set of common structural components that usually are the building blocks of basement membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed59aca5ae453a9c453e07266af47f53
https://doi.org/10.1385/jmn:24:1:167
https://doi.org/10.1385/jmn:24:1:167