Výsledky vyhledávání - "John B Wojcik"

Abstract P4-09-07: Characterization of Immune Contexture in HR+/HER2- and Triple Negative Breast Cancer in a Real-world Cohort

Autor: Aparna Chhibber, Lloye M. Dillon, John B. Wojcik, Vishantie Dostal, George Lee, Fayaz Seifuddin, Scott Ely, Mark D. Stern, Charlie Benson-Garnett, Mustimbo Roberts, Jenny Wu

Publikováno v: Cancer Research. 83:P4-09

Background: Prior studies in breast cancer (BC) have demonstrated variability in the immune microenvironment of BCs across subtypes, with higher levels of immune infiltration observed in triple-negative (TN) BC. Clinical trials of immunotherapy in BC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8a77c1813ec3045af35bb18f1a4f4e5
https://doi.org/10.1158/1538-7445.sabcs22-p4-09-07

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Supplementary Tables S1-S5 from Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors

Autor: Benjamin A. Garcia, Jacek Majewski, Amanda Lisby, Anissa Djedid, Simone Sidoli, Dylan M. Marchione, John B. Wojcik

Tabbed excel spreadsheet with each tab representing a single supplementary table. The first cell of each tab contains a description of the contents. Supplemental Table 1: Log2 normalized protein abundances of proteins identified in FFPE MPNST samples

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https://doi.org/10.1158/0008-5472.22421621.v1

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Data from Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors

Autor: Benjamin A. Garcia, Jacek Majewski, Amanda Lisby, Anissa Djedid, Simone Sidoli, Dylan M. Marchione, John B. Wojcik

Malignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with recurrent loss-of-function alterations in polycomb-repressive complex 2 (PRC2), a histone-modifying complex involved in transcriptional silencing. To understand the role of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ae3041ed34aee9a0435889c9c96d34e
https://doi.org/10.1158/0008-5472.c.6510974.v1

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Measurement of LAG-3 Expression Across Multiple Staining Platforms With the 17B4 Antibody Clone

Autor: John B. Wojcik, Keyur Desai, Konstantinos Avraam, Arno Vandebroek, Lloye M. Dillon, Giorgia Giacomazzi, Charlotte Rypens, Joseph L. Benci

Publikováno v: Archives of Pathology & Laboratory Medicine.

Context.— An immunohistochemistry (IHC) assay developed to detect lymphocyte-activation gene 3 (LAG-3), a novel immune checkpoint inhibitor target, has demonstrated high analytic precision and interlaboratory reproducibility using a Leica staining

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::851a65a9904b8a8e1aa685bdbdd97654
https://doi.org/10.5858/arpa.2022-0082-oa

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Development of a LAG-3 Immunohistochemistry Assay for Melanoma

Autor: Lori Johnson, Bryan McCune, Darren Locke, Cyrus Hedvat, John B Wojcik, Caitlin Schroyer, Jim Yan, Krystal Johnson, Angela Sanders-Cliette, Sujana Samala, Lloye M Dillon, Steven Anderson, Jeffrey Shuster

AimsA robust immunohistochemistry (IHC) assay was developed to detect lymphocyte-activation gene 3 (LAG-3) expression by immune cells (ICs) in tumor tissues. LAG-3 is an immuno-oncology target with demonstrable clinical benefit, and there is a need f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44433ff664252fc81d6b391199a041a
https://doi.org/10.1101/2022.02.25.481964

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Consistent measurement of LAG-3 expression across multiple staining platforms with the 17B4 antibody clone

Autor: John B. Wojcik, Keyur Desai, Konstantinos Avraam, Arno Vandebroek, Lloye M. Dillon, Giorgia Giacomazzi, Charlotte Rypens, Joseph L. Benci

ContextAn immunohistochemistry (IHC) assay developed to detect lymphocyte-activation gene 3 (LAG-3), a novel immune checkpoint inhibitor target, has demonstrated high analytical precision and interlaboratory reproducibility using a Leica staining pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94982946099f3b254cd1d4b07eb1a0ad
https://doi.org/10.1101/2022.02.21.481075

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Early Onset Post-Radiation Cutaneous Angiosarcoma of the Breast with Features of Atypical-Vascular Lesion: A Diagnostic Pitfall and Its Biologic Significance

Autor: Brian J. Czerniecki, John B. Wojcik, Paul J. Zhang

Publikováno v: Case Reports in Clinical Medicine. :203-208

Vascular proliferations may arise in the breast following radiation treatment for a primary breast adenocarcinoma. A post-radiation vascular proliferation can usually be classified as angiosarcoma or as an atypical vascular lesion (AVL). Angiosarcoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53a50093fac2a35e5ad46582589fe0c0
https://doi.org/10.4236/crcm.2015.46041

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