Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John B Tillman"'
Autor:
Douglas Linville, Devin K. Datta, John B Tillman, Douglas P. Beall, Richard W Easton, James R Webb, Sanjay Talati, John Amburgy, Bradly S. Goodman, M. R. Chambers, Samuel M Thomas
Publikováno v:
Neurosurgery
BACKGROUND Osteoporotic and neoplastic vertebral compression fractures (VCF) are common and painful, threatening quality of life and increasing risk of morbidity and mortality. Balloon kyphoplasty is a percutaneous option for treating painful cancer-
Autor:
James, Berenson, Robert, Pflugmacher, Peter, Jarzem, Jeffrey, Zonder, Kenneth, Schechtman, John B, Tillman, Leonard, Bastian, Talat, Ashraf, Frank, Vrionis, F, Vrionis
Publikováno v:
The Lancet Oncology. 12:225-235
Non-randomised trials have reported benefits of kyphoplasty in patients with cancer and vertebral compression fractures (VCFs). We aimed to assess the efficacy and safety of balloon kyphoplasty compared with non-surgical management for patients with
Autor:
John B. Tillman, Monica A. Madore, Patricia L. Mote, Stephen R. Spindler, Shelley X. Cao, Joseph M. Dhahbi, Roy L. Walford
Publikováno v:
Biochemical and Biophysical Research Communications. 284:335-339
Calorie restriction (CR) delays age-related physiological changes, reduces cancer incidence, and increases maximum life span in mammals. Here we show that CR decreased the expression of many hepatic molecular chaperones and concomitantly increased th
Autor:
Carol A. Haussler, Stephen R. Spindler, John B. Tillman, Peter W. Jurutka, G. Kerr Whitfield, Jui Cheng Hsieh, Mark R. Haussler, Michael A. Galligan, Paul Thompson
Publikováno v:
Journal of Cellular Biochemistry. 75:462-480
The vitamin D receptor (VDR) is a transcription factor believed to function as a heterodimer with the retinoid X receptor (RXR). However, it was reported [Schrader et al., 1994] that, on putative vitamin D response elements (VDREs) within the rat 9k
Autor:
John B. Tillman, Patricia L. Mote, Stephen R. Spindler, Joseph M. Dhahbi, John Wingo, Roy L. Walford
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 277:E352-E360
We characterized the effects of calorie restriction (CR) on the expression of key glycolytic, gluconeogenic, and nitrogen-metabolizing enzymes in mice. Of the gluconeogenic enzymes investigated, liver glucose-6-phosphatase mRNA increased 1.7- and 2.3
Autor:
Patricia L. Mote, Roy L. Walford, Shelley X. Cao, John B. Tillman, Stephen R. Spindler, Joseph M. Dhahbi
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :B180-B185
The free radical theory of aging predicts that calorie restriction, which extends life span, should reduce oxidant damage. In mammals, the oxidative processes centered in the liver are a major source of free radicals. Liver catalase has the dominant
Publikováno v:
The Journal of Nutrition. 127:1758-1764
A number of putative molecular chaperones seem to play essential roles in the correct folding, assembly and glycosylation of membrane and secreted proteins in the endoplasmic reticulum. We have shown that life span-extending dietary energy restrictio
Publikováno v:
The Journal of Nutrition. 126:416-423
Dietary energy restriction delays age-related physiologic changes, increases maximum life span, and reduces cancer incidence. We showed previously that 50% energy restriction in mice reduces hepatic expression of glucose-regulated protein mRNA by 50
Publikováno v:
Journal of Biological Chemistry. 271:3500-3506
Dietary calorie restriction (CR) delays age-related physiologic changes, increases maximum life span, and reduces cancer incidence. Here, we present the novel finding that chronic reduction of dietary calories by 50% without changing the intake of di
Publikováno v:
Gene. 158:225-229
Dietary calorie restriction, also termed energy restriction, increases mean and maximum life span, reduces the incidence of tumors and increases the mean age of onset of diseases and tumors in every animal tested. Because life-span is genetically det