Zobrazeno 1 - 10
of 199
pro vyhledávání: '"John B Thomas"'
Autor:
Cristiana Dondi, Georg Vogler, Anjali Gupta, Stanley M. Walls, Anaïs Kervadec, James Marchant, Michaela R. Romero, Soda Diop, Jason Goode, John B. Thomas, Alex R. Colas, Rolf Bodmer, Marc Montminy, Karen Ocorr
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114549- (2024)
Summary: CREB-regulated transcription co-activator (CRTC) is activated by Calcineurin (CaN) to regulate gluconeogenic genes. CaN also has roles in cardiac hypertrophy. Here, we explore a cardiac-autonomous role for CRTC in cardiac hypertrophy. In Dro
Externí odkaz:
https://doaj.org/article/c996134180b94600beaae178614fec84
Autor:
Renee D Read, Tim R Fenton, German G Gomez, Jill Wykosky, Scott R Vandenberg, Ivan Babic, Akio Iwanami, Huijun Yang, Webster K Cavenee, Paul S Mischel, Frank B Furnari, John B Thomas
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003253 (2013)
Glioblastoma, the most common primary malignant brain tumor, is incurable with current therapies. Genetic and molecular analyses demonstrate that glioblastomas frequently display mutations that activate receptor tyrosine kinase (RTK) and Pi-3 kinase
Externí odkaz:
https://doaj.org/article/f66c2079edd64ea7b75880e80cd51118
Publikováno v:
PLoS Genetics, Vol 5, Iss 2, p e1000374 (2009)
Gliomas, the most common malignant tumors of the nervous system, frequently harbor mutations that activate the epidermal growth factor receptor (EGFR) and phosphatidylinositol-3 kinase (PI3K) signaling pathways. To investigate the genetic basis of th
Externí odkaz:
https://doaj.org/article/0c0ad001c6d14b98b2df74461f623cfb
Publikováno v:
The Journal of Neuroscience. 36:1140-1150
Receptors on the growth cone at the leading edge of elongating axons play critical guidance roles by recognizing cues via their extracellular domains and transducing signals via their intracellular domains, resulting in changes in direction of growth
Autor:
Shingo Yoshikawa, Helene Babski, Alain Garces, Jean Valmier, Clement Surel, John B. Thomas, Patrick Carroll
Interneurons (INs) coordinate motoneurons activity to generate adequate patterns of muscle contractions, providing animals with the ability to adjust their body posture and to move over a range of speeds. In theDrosophilalarvae several IN subtypes ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780e7b14e580cabb2d81139b86f20af8
Publikováno v:
Geological Society of America Abstracts with Programs.
Publikováno v:
Shen, R; Wang, B; Giribaldi, MG; Ayres, J; Thomas, JB; & Montminy, M. (2016). Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(23), E3307-E3314. doi: 10.1073/pnas.1606106113. UCSF: Retrieved from: http://www.escholarship.org/uc/item/66f73464
The starvation-inducible coactivator cAMP response element binding protein (CREB)-cAMP-regulated transcription coactivator (Crtc) has been shown to promote starvation resistance in Drosophila by up-regulating CREB target gene expression in neurons, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d86a0c56c8d966cdafc13b0b6d370f7
http://www.escholarship.org/uc/item/66f73464
http://www.escholarship.org/uc/item/66f73464
Autor:
Jim Carl, Kay Morris Matthews, John B. Thomas, Nathan Roberts, Deborah Thom, Gary McCulloch, Michael Shattock
Publikováno v:
History of Education. 39:417-435
Autor:
Kieran R. Byrne, Ruth Watts, Peter Gordon, John B. Thomas, Thomas O'Brien, Brendan Carmody, Dennis Dean
Publikováno v:
History of Education. 38:705-720
Autor:
Shingo Yoshikawa, Kei Ito, Kyoko Ishikawa, Chihiro Hama, Linda A. Santschi, John B. Thomas, Masao Sakurai, Tomoko Aoki, Ken-ichi Kimura, Keita Endo, Hiroko Saito
Publikováno v:
The Journal of Neuroscience. 29:4972-4980
InDrosophila, odor information received by olfactory receptor neurons (ORNs) is processed by glomeruli, which are organized in a stereotypic manner in the antennal lobe (AL). This glomerular organization is regulated by Wnt5 signaling. In the embryon