Zobrazeno 1 - 10
of 14
pro vyhledávání: '"John B Presloid"'
Autor:
Adaeze O Izuogu, Kristin L McNally, Stephen E Harris, Brian H Youseff, John B Presloid, Christopher Burlak, Jason Munshi-South, Sonja M Best, R Travis Taylor
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179781 (2017)
Tick-borne flaviviruses (TBFVs), including Powassan virus and tick-borne encephalitis virus cause encephalitis or hemorrhagic fevers in humans with case-fatality rates ranging from 1-30%. Despite severe disease in humans, TBFV infection of natural ro
Externí odkaz:
https://doaj.org/article/5bf74743187f459c9d747618a6488809
Autor:
Brian H. Youseff, Thomas G. Brewer, Kristin L. McNally, Adaeze O. Izuogu, Kirk J. Lubick, John B. Presloid, Saad Alqahtani, Saurabh Chattopadhyay, Sonja M. Best, Xiche Hu, R. Travis Taylor
Publikováno v:
iScience, Vol 15, Iss , Pp 489-501 (2019)
Summary: Tick-borne flaviviruses (TBFVs) can cause life-threatening encephalitis and hemorrhagic fever. To identify virus-host interactions that may be exploited as therapeutic targets, we analyzed the TBFV polyprotein in silico for antiviral protein
Externí odkaz:
https://doaj.org/article/2689687ad01c41adb8ca44fe7f6df55a
Autor:
John B. Presloid, Isabel S. Novella
Publikováno v:
Viruses, Vol 7, Iss 6, Pp 3226-3240 (2015)
Due to high mutation rates, populations of RNA viruses exist as a collection of closely related mutants known as a quasispecies. A consequence of error-prone replication is the potential for rapid adaptation of RNA viruses when a selective pressure i
Externí odkaz:
https://doaj.org/article/341e6f6c93b344148047498fa19e5b69
Autor:
Benjamin W French, Steven T. Haller, Robin C. Su, Robert E. McCullumsmith, Prabhatchandra Dube, John B. Presloid, Fatimah K Khalaf, Khaled Alganem, Joshua D. Breidenbach, Deepak Malhotra, David J Kennedy, R. Mark Wooten
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9939, p 9939 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9939, p 9939 (2021)
We were the first to previously report that microcystin-LR (MC-LR) has limited effects within the colons of healthy mice but has toxic effects within colons of mice with pre-existing inflammatory bowel disease. In the current investigation, we aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44492b4cabb0206a3f89e00aa8866173
Autor:
Thomas G. Brewer, Kirk J. Lubick, Adaeze O. Izuogu, Saurabh Chattopadhyay, Saad Alqahtani, Kristin L. McNally, John B. Presloid, Sonja M. Best, Xiche Hu, Brian H. Youseff, R. Travis Taylor
Publikováno v:
iScience, Vol 15, Iss, Pp 489-501 (2019)
iScience
iScience
Summary Tick-borne flaviviruses (TBFVs) can cause life-threatening encephalitis and hemorrhagic fever. To identify virus-host interactions that may be exploited as therapeutic targets, we analyzed the TBFV polyprotein in silico for antiviral protein-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48409536fe03ef4bac110c4cdd361fc1
http://www.sciencedirect.com/science/article/pii/S2589004219301476
http://www.sciencedirect.com/science/article/pii/S2589004219301476
Publikováno v:
Virology. 496:203-214
The theory of plastogenetic congruence posits that ultimately, the pressure to maintain function in the face of biomolecular destabilization produces robustness. As temperature goes up so does destabilization. Thus, genetic robustness, defined as phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1c25774a95fb1aece32fab740bf0de
Autor:
Isabel S. Novella, John B. Presloid
Publikováno v:
Viruses
Viruses, Vol 7, Iss 6, Pp 3226-3240 (2015)
Viruses, Vol 7, Iss 6, Pp 3226-3240 (2015)
Due to high mutation rates, populations of RNA viruses exist as a collection of closely related mutants known as a quasispecies. A consequence of error-prone replication is the potential for rapid adaptation of RNA viruses when a selective pressure i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224b07bce9e2e0c2997c9863b41ff234
https://doi.org/10.3390/v7062768
https://doi.org/10.3390/v7062768
Autor:
John B. Presloid, Jason Munshi-South, Christopher Burlak, R. Travis Taylor, Kristin L. McNally, Stephen E. Harris, Adaeze O. Izuogu, Sonja M. Best, Brian H. Youseff
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0179781 (2017)
PLoS ONE, Vol 12, Iss 6, p e0179781 (2017)
Tick-borne flaviviruses (TBFVs), including Powassan virus and tick-borne encephalitis virus cause encephalitis or hemorrhagic fevers in humans with case-fatality rates ranging from 1-30%. Despite severe disease in humans, TBFV infection of natural ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37abebd0ed068b53226e069583e2099b
https://pubmed.ncbi.nlm.nih.gov/28650973
https://pubmed.ncbi.nlm.nih.gov/28650973
Publikováno v:
Journal of Virology. 87:4923-4928
Quasispecies theory is a case of mutation-selection balance for evolution at high mutation rates, such as those observed in RNA viruses. One of the main predictions of this model is the selection for robustness, defined as the ability of an organism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532a618655e184867571f3ec0cfbda18
https://doi.org/10.1128/jvi.02796-12
https://doi.org/10.1128/jvi.02796-12
Autor:
Claus O. Wilke, Kim L. Lust, Sarah D. Smith-Tsurkan, Ranendra N. Dutta, Tong Zhou, Bonnie E. Ebendick-Corpus, John B. Presloid, Isabel S. Novella
Publikováno v:
Journal of Virology. 84:4960-4968
Virus strains with a history of repeated genetic bottlenecks frequently show a diminished ability to adapt compared to strains that do not have such a history. These differences in adaptability suggest differences in either the rate at which benefici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f798c75c96913f5f22e4c87945ab1e0
https://doi.org/10.1128/jvi.00710-09
https://doi.org/10.1128/jvi.00710-09