Zobrazeno 1 - 10
of 58
pro vyhledávání: '"John B Patterson"'
Autor:
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares‐Lupon, Kathleen Schmit, Pierre‐Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Eric Chevet
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/61cb6bd968494a5cbfe714a2a5fc6f79
Autor:
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares‐Lupon, Kathleen Schmit, Pierre‐Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Eric Chevet
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 2, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/8199033c7c474113aec49c675fdc3783
Autor:
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares‐Lupon, Kathleen Schmit, Pierre‐Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Eric Chevet
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 3, Pp 1-20 (2018)
Abstract Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical role in cancer deve
Externí odkaz:
https://doaj.org/article/fc9d46f9f6e245f98478a5229ed883cb
Autor:
Amy S. Lee, Susan E. Bates, John B. Patterson, Caryn Stiles, Frank Markland, Fritz Costa, Steven Swenson, Peter Baumeister, Bryce Ko, Dezheng Dong
Therapeutic targeting of the tumor vasculature that destroys preexisting blood vessels of the tumor and antiangiogenesis therapy capitalize on the requirement of tumor cells on an intact vascular supply for oxygen and nutrients for growth, expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb276a5ed007a8a768f2ba0d98125ac
https://doi.org/10.1158/0008-5472.c.6493880
https://doi.org/10.1158/0008-5472.c.6493880
Autor:
Amy S. Lee, Susan E. Bates, John B. Patterson, Caryn Stiles, Frank Markland, Fritz Costa, Steven Swenson, Peter Baumeister, Bryce Ko, Dezheng Dong
Supplementary Data from Vascular Targeting and Antiangiogenesis Agents Induce Drug Resistance Effector GRP78 within the Tumor Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27cf682b88ff0f887819ba7ed130295
https://doi.org/10.1158/0008-5472.22363754.v1
https://doi.org/10.1158/0008-5472.22363754.v1
Autor:
Stuart Creedican, Claire M. Robinson, Katarzyna Mnich, Md Nahidul Islam, Eva Szegezdi, Ruth Clifford, Janusz Krawczyk, John B. Patterson, Stephen P. FitzGerald, Mark Summers, Ciaran Richardson, Kenneth Martin, Adrienne M. Gorman, Afshin Samali
Publikováno v:
Journal of cellular and molecular medicine. 26(16)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b999248ae3ecb6d7835f0dd0c51e3e6
https://pubmed.ncbi.nlm.nih.gov/35822520
https://pubmed.ncbi.nlm.nih.gov/35822520
Autor:
Tim H. Brümmendorf, Azam Salimi, Christian Preisinger, Iris Appelmann, Afshin Samali, Mirle Schemionek, John B. Patterson, Margherita Vieri, Behzad Kharabi Masouleh
Publikováno v:
Carcinogenesis. 42:272-284
BCR-ABL1-positive acute lymphoblastic leukemia (ALL) cell survival is dependent on the inositol-requiring enzyme 1 alpha (IRE1α) branch of the unfolded protein response. In the current study, we have focused on exploring the efficacy of a simultaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b934a06ec41bfd14decd57c9fedb2630
https://doi.org/10.1093/carcin/bgaa095
https://doi.org/10.1093/carcin/bgaa095
Publikováno v:
Nature Chemical Biology. 15:764-775
Accumulation of unfolded proteins at the endoplasmic reticulum (ER) is a salient attribute of many human diseases including obesity, liver disorders, cancer, diabetes and neurodegeneration. To restore ER proteostasis, cells activate the unfolded prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d61b7c8dd770f0d3bf475e55736230f
https://doi.org/10.1038/s41589-019-0326-2
https://doi.org/10.1038/s41589-019-0326-2
Autor:
John B. Patterson, Shahla Shojaei, Zohreh Mostafavi-Pour, Sanaz Dastghaib, Pawan K. Sharma, Afshin Samali, Pooneh Mokarram, Saeid Ghavami
Publikováno v:
Cells, Vol 9, Iss 2339, p 2339 (2020)
Cells
Volume 9
Issue 11
Cells
Volume 9
Issue 11
Glioblastoma (GBM) is the most prevalent malignant primary brain tumor with a very poor survival rate. Temozolomide (TMZ) is the common chemotherapeutic agent used for GBM treatment. We recently demonstrated that simvastatin (Simva) increases TMZ-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a4d4dff429df9a5636ce770fda6c56
https://www.mdpi.com/2073-4409/9/11/2339
https://www.mdpi.com/2073-4409/9/11/2339
Autor:
Susan E. Logue, Afshin Samali, Nadezda Dolgikh, Nicole McCarthy, Adrienne M. Gorman, Qinping Zeng, Simone Fulda, John B. Patterson
Publikováno v:
Cancer letters. 490
Rhabdomyosarcoma (RMS), the most common soft-tissue sarcoma, is associated with a low 5-year survival and harsh treatment side effects, underscoring an urgent need for therapy. The unfolded protein response (UPR) is activated in response to endoplasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414e71781597412363c245c675ca653f
https://pubmed.ncbi.nlm.nih.gov/32679165
https://pubmed.ncbi.nlm.nih.gov/32679165