Zobrazeno 1 - 10 of 10 pro vyhledávání: '"John B O'Connor"'
1
Akademický článek
Divergence of bacterial communities in the lower airways of CF patients in early childhood.
Autor: John B O'Connor, Madison M Mottlowitz, Brandie D Wagner, Kathleen L Boyne, Mark J Stevens, Charles E Robertson, Jonathan K Harris, Theresa A Laguna
Publikováno v: PLoS ONE, Vol 16, Iss 10, p e0257838 (2021)
RationaleChronic airway infection and inflammation resulting in progressive, obstructive lung disease is the leading cause of morbidity and mortality in cystic fibrosis. Understanding the lower airway microbiota across the ages can provide valuable i
Externí odkaz: https://doaj.org/article/d0321265d8184464ad546af551bcee45
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2
Akademický článek
An integrated metaproteomics workflow for studying host-microbe dynamics in bronchoalveolar lavage samples applied to cystic fibrosis disease
Autor: Monica E. Kruk, Subina Mehta, Kevin Murray, LeeAnn Higgins, Katherine Do, James E. Johnson, Reid Wagner, Chris H. Wendt, John B. O’Connor, J. Kirk Harris, Theresa A. Laguna, Pratik D. Jagtap, Timothy J. Griffin
Publikováno v: mSystems, Vol 9, Iss 7 (2024)
ABSTRACT Airway microbiota are known to contribute to lung diseases, such as cystic fibrosis (CF), but their contributions to pathogenesis are still unclear. To improve our understanding of host-microbe interactions, we have developed an integrated a
Externí odkaz: https://doaj.org/article/e36a430e5a754b0e804f12b6ccd9536c
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3
Akademický článek
Detection and identification of fungi in the lower airway of children with and without cystic fibrosis
Autor: John B. O’Connor, Brandie D. Wagner, J. Kirk Harris, Daniel N. Frank, Diana E. Clabots, Theresa A. Laguna
Publikováno v: Frontiers in Microbiology, Vol 14 (2023)
IntroductionAirway infection and inflammation lead to the progression of obstructive lung disease in persons with cystic fibrosis (PWCF). However, cystic fibrosis (CF) fungal communities, known drivers of CF pathophysiology, remain poorly understood
Externí odkaz: https://doaj.org/article/6c4c54828ce34dc581befcf5b9402f63
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4
Seizure Semiology and Response to Treatment in a Pediatric Cohort withSCN2AVariants: A Parent Report
Autor: John B. O’Connor, Emily B. Kirschenblatt, Linda Laux, Anne T. Berg, Sunita N. Misra, John J. Millichap
We examined seizure semiology and response to medications in 28 children (9 female, 19 male) with likely pathogenic and pathogenicSCN2A-related epilepsy. Parents reported seizure onset, seizure semiology, genetic variants, therapies used for seizures
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::772fdc5b0ca19a18827433384da1da94
https://doi.org/10.1101/2023.02.23.23286378
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5
Network Analysis to Identify Multi-Omic Correlations in the Lower Airways of Children With Cystic Fibrosis
Autor: John B, O'Connor, Madison, Mottlowitz, Monica E, Kruk, Alan, Mickelson, Brandie D, Wagner, Jonathan Kirk, Harris, Christine H, Wendt, Theresa A, Laguna
Publikováno v: Frontiers in Cellular and Infection Microbiology. 12
The leading cause of morbidity and mortality in cystic fibrosis (CF) is progressive lung disease secondary to chronic airway infection and inflammation; however, what drives CF airway infection and inflammation is not well understood. By providing a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c665b19a4a3297a7e35ef22430b327ad
https://doi.org/10.3389/fcimb.2022.805170
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6
Divergence of bacterial communities in the lower airways of CF patients in early childhood
Autor: Madison M. Mottlowitz, Brandie D. Wagner, Charles E. Robertson, John B. O’Connor, Theresa A. Laguna, Kathleen L. Boyne, Jonathan K. Harris, Mark J. Stevens
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0257838 (2021)
Rationale Chronic airway infection and inflammation resulting in progressive, obstructive lung disease is the leading cause of morbidity and mortality in cystic fibrosis. Understanding the lower airway microbiota across the ages can provide valuable
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb8b3cc02bc671e3924ec7d054fbc6e
http://europepmc.org/articles/PMC8494354
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10
Non-Tuberculous Pulmonary Apical Disease
Autor: John B. O'Connor, John N. Hayes
Publikováno v: Diseases of the Chest. 4:10-13
fidence. Notonly does sucha program bring the patient through his treatment but it relieves him of that awful defeatism which pervades the one whohas nothadtheproper psychical aid and the proper physical rehabilitation. It toomakes the treatment as p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e3461f3bb2432016fe85fde0584eea4
https://doi.org/10.1378/chest.4.1.10
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