Zobrazeno 1 - 10
of 274
pro vyhledávání: '"John B Gurdon"'
Publikováno v:
PLoS Biology, Vol 9, Iss 11, p e1001197 (2011)
Incompatibilities between the nucleus and the cytoplasm of sufficiently distant species result in developmental arrest of hybrid and nucleocytoplasmic hybrid (cybrid) embryos. Several hypotheses have been proposed to explain their lethality, includin
Externí odkaz:
https://doaj.org/article/0d3a4e9484934e51af03556f98f329a0
Autor:
Kei Miyamoto, Khoi T. Nguyen, George E. Allen, Jerome Jullien, Dinesh Kumar, Tomoki Otani, Charles R. Bradshaw, Frederick J. Livesey, Manolis Kellis, John B. Gurdon
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 304-311 (2018)
Summary: Oocytes have a remarkable ability to reactivate silenced genes in somatic cells. However, it is not clear how the chromatin architecture of somatic cells affects this transcriptional reprogramming. Here, we investigated the relationship betw
Externí odkaz:
https://doaj.org/article/ca56751c6eef410796572fb95a15ed4d
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Some kinds of transcription factor proteins are very important in initiating and guiding cell fate differentiation. Overexpression of these factors can force many other kinds of cells to become muscle or nerve. Examples are MyoD for musc
Autor:
Benjamin D. Simons, Tom W. Hiscock, John C. Marioni, Jerome Jullien, John B. Gurdon, Can Aztekin
Publikováno v:
Science. 364:653-658
A tale of tadpole tail regeneration Some vertebrates, including some amphibians, show a remarkable, if sometimes restricted, ability to regenerate lost appendages. Aztekin et al. compared naturally occurring regeneration-competent and -incompetent Xe
Autor:
John B. Gurdon, Tom W. Hiscock, Can Aztekin, John C. Marioni, Benjamin D. Simons, Jerome Jullien
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Absence of a specialized wound epidermis is hypothesized to block limb regeneration in higher vertebrates. However, the factors preventing its formation in regeneration-incompetent animals are poorly understood. To characterize the endogenous molecul
Autor:
Edward M, De Robertis, John B, Gurdon
Publikováno v:
Cold Spring Harbor protocols. 2021(12)
Autor:
Vincent Gaggioli, Declan Keane, Laurent David, Valar Nila Roamio Franklin, Matthieu Sporniak, Mami Oikawa, Kamal Kishore, Thomas Fréour, John B. Gurdon, Marta Teperek, Alan M. O'Doherty, Angela Simeone, Clive D'Santos, Charles R. Bradshaw, Jerome Jullien, Eva Hormanseder, Emma Falk, Adrian T. Grzybowski, Alexander J. Ruthenburg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.3491. ⟨10.1038/s41467-020-17238-w⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3491. ⟨10.1038/s41467-020-17238-w⟩
Nature Communications
Nature Communications, 2020, 11 (1), pp.3491. ⟨10.1038/s41467-020-17238-w⟩
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3491. ⟨10.1038/s41467-020-17238-w⟩
Sperm contributes genetic and epigenetic information to the embryo to efficiently support development. However, the mechanism underlying such developmental competence remains elusive. Here, we investigated whether all sperm cells have a common epigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2301704281b01054db70ccb9bd0c7247
https://www.repository.cam.ac.uk/handle/1810/325577
https://www.repository.cam.ac.uk/handle/1810/325577
Autor:
Jerome Jullien, John C. Marioni, Tom W. Hiscock, Benjamin D. Simons, John B. Gurdon, Can Aztekin
Absence of a specialised wound epidermis is hypothesised to block limb regeneration in higher vertebrates. To elucidate the cellular and molecular determinants of this tissue, we performed single-cell transcriptomics in regeneration-competent, -restr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d68cb501b3b4b7ef28986a7e20c0790c
https://doi.org/10.1101/2020.06.01.127654
https://doi.org/10.1101/2020.06.01.127654
Autor:
Magdalena J. Koziol, John B. Gurdon
Publikováno v:
Biochemistry Research International, Vol 2012 (2012)
The translationally controlled tumor protein (TCTP) is highly conserved among animal species. It is widely expressed in many different tissues. It is involved in regulating many fundamental processes, such as cell proliferation and growth, apoptosis,
Externí odkaz:
https://doaj.org/article/add4661ca58440db96908e818dbc203d
Autor:
Richard Butler, Can Aztekin, Francisco De Jesús Andino, Jacques Robert, Tom W. Hiscock, Jerome Jullien, John B. Gurdon
Publikováno v:
Development (Cambridge, England)
Regeneration-competent vertebrates are considered to suppress inflammation faster than non-regenerating ones. Hence, understanding the cellular mechanisms affected by immune cells and inflammation can help develop strategies to promote tissue repair