Zobrazeno 1 - 10
of 79
pro vyhledávání: '"John B, Rafferty"'
Autor:
Aditi Kaushik, Thane Than, Naomi J. Petela, Menelaos Voulgaris, Charlotte Percival, Peter Daniels, John B. Rafferty, Kim A. Nasmyth, Bin Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The ring-shaped cohesin complex is a key player in sister chromatid cohesion, DNA repair, and gene transcription. The loading of cohesin to chromosomes requires the loader Scc2 and is regulated by ATP. This process is hindered by Smc3 acetyl
Externí odkaz:
https://doaj.org/article/e4e084eb182e4def97ed322fff146195
Autor:
Alicia M. Churchill-Angus, Thomas H. B. Schofield, Thomas R. Marlow, Svetlana E. Sedelnikova, Jason S. Wilson, John B. Rafferty, Patrick J. Baker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Tripartite members of the ClyA family of α-PFTs have recently been identified in a number of pathogenic Gram-negative bacteria, including the human pathogen Serratia marcescens. Structures of a Gram-negative A component and a tripartite α-
Externí odkaz:
https://doaj.org/article/2c7f359be7964752aa45970e9a0857dc
Autor:
Daniel J. Bennison, Jose A. Nakamoto, Timothy D. Craggs, Pohl Milón, John B. Rafferty, Rebecca M. Corrigan
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of a stress signaling network termed the stringent response. RsgA, RbgA, Era, and HflX are four ribosome-associated GTPases (RA-GTPases) that bind to (p)ppGpp i
Externí odkaz:
https://doaj.org/article/30d2fbf8331d4dca84c56f46e5ca1dd8
Autor:
Jason S. Wilson, Alicia M. Churchill-Angus, Simon P. Davies, Svetlana E. Sedelnikova, Svetomir B. Tzokov, John B. Rafferty, Per A. Bullough, Claudine Bisson, Patrick J. Baker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Pore forming toxins (PFTs) form the major group of virulence factors in many pathogenic bacteria. Here the authors identify tripartite α-helical PFTs in pathogenic Gram negative bacteria and structurally characterize AhlABC from Aeromonas hydrophila
Externí odkaz:
https://doaj.org/article/2f6b67a180744391895b4f4a9d6daa29
Autor:
John B. Rafferty, Jose A. Nakamoto, Rebecca M. Corrigan, Pohl Milón, Timothy D. Craggs, Daniel J. Bennison
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of a stress signaling network termed the stringent response. RsgA, RbgA, Era, and HflX are four ribosome-associated GTPases (RA-GTPases) that bind to (p)ppGpp in Staphyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2de82a6d991fea9b06a91814ad152fc
https://doi.org/10.1128/mbio.02679-21
https://doi.org/10.1128/mbio.02679-21
Publikováno v:
Journal of Molecular Biology. 431:351-367
C4-dicarboxylates play a central role in cellular physiology as key metabolic intermediates. Under aerobic conditions, they participate in the citric acid cycle, while in anaerobic bacteria, they are important in energy-conserving fermentation and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd5dd393c70a74cdccba0368bef2b1c
https://doi.org/10.1016/j.jmb.2018.11.016
https://doi.org/10.1016/j.jmb.2018.11.016
Autor:
Svetlana E. Sedelnikova, Alicia M. Churchill-Angus, Thomas R. Marlow, Thomas H. B. Schofield, John B. Rafferty, Jason S. Wilson, Patrick J. Baker
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Tripartite members of the ClyA family of α-PFTs have recently been identified in a number of pathogenic Gram-negative bacteria, including the human pathogen Serratia marcescens. Structures of a Gram-negative A component and a tripartite α-PFT compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9249b9ed95b0f30bada9178a3fdddc38
https://doi.org/10.1038/s41598-021-85726-0
https://doi.org/10.1038/s41598-021-85726-0
Autor:
John B. Rafferty, Pohl Milón, Timothy D. Craggs, Jose A. Nakamoto, Rebecca M. Corrigan, Daniel J. Bennison
During nutrient limitation, bacteria produce the alarmones (p)ppGpp as effectors of the stress signalling network termed the stringent response. Screening for (p)ppGpp-binding targets within Staphylococcus aureus identified four ribosome-associated G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3cb2cebd1fb66e4a76fe78be6e65867
https://doi.org/10.1101/2021.01.19.427108
https://doi.org/10.1101/2021.01.19.427108
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59844 (2013)
The biodegradation of lignin, one of the most abundant carbon compounds on Earth, has important biotechnological applications in the derivation of useful products from lignocellulosic wastes. The purple photosynthetic bacterium Rhodopseudomonas palus
Externí odkaz:
https://doaj.org/article/812ef6e6b1254741ae20c375fd343f57
Publikováno v:
The FEBS Journal. 284:4262-4277
The Tripartite Tricarboxylate Transporter (TTT) family is a poorly characterised group of prokaryotic secondary solute transport systems, which employ a periplasmic substrate binding-protein (SBP) for initial ligand recognition. The substrates of onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e99b85532a84ab0cb8caf38f6501e40
https://doi.org/10.1111/febs.14304
https://doi.org/10.1111/febs.14304