Zobrazeno 1 - 10
of 564
pro vyhledávání: '"John B, Harley"'
Autor:
John B Harley, Viktoryia Laurynenka, Sreeja Parameswaran, Xiaoting Chen, Leah C Kottyan, Matthew T Weirauch, Kenneth M Kaufman, Iouri Chepelev
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/78b17783b62447819ce41c9c2d6c3904
Autor:
John B Harley, Viktoryia Laurynenka, Kenneth M Kaufman, Celi Sun, R Hal Scofield, Dennis H Clark, Iouri Chepelev, Isaac TW Harley
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/65680f42dc8e4ce4a69f5d210a30f9cc
Autor:
John B Harley, Viktoryia Laurynenka, Kenneth M Kaufman, Celi Sun, R Hal Scofield, Dennis H Clark, Iouri Chepelev, Isaac TW Harley
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/87405e5803704bd7972b350a3d74d1c4
Autor:
Lili Liu, Atlas Khan, Elena Sanchez-Rodriguez, Francesca Zanoni, Yifu Li, Nicholas Steers, Olivia Balderes, Junying Zhang, Priya Krithivasan, Robert A. LeDesma, Clara Fischman, Scott J. Hebbring, John B. Harley, Halima Moncrieffe, Leah C. Kottyan, Bahram Namjou-Khales, Theresa L. Walunas, Rachel Knevel, Soumya Raychaudhuri, Elizabeth W. Karlson, Joshua C. Denny, Ian B. Stanaway, David Crosslin, Thomas Rauen, Jürgen Floege, Frank Eitner, Zina Moldoveanu, Colin Reily, Barbora Knoppova, Stacy Hall, Justin T. Sheff, Bruce A. Julian, Robert J. Wyatt, Hitoshi Suzuki, Jingyuan Xie, Nan Chen, Xujie Zhou, Hong Zhang, Lennart Hammarström, Alexander Viktorin, Patrik K. E. Magnusson, Ning Shang, George Hripcsak, Chunhua Weng, Tatjana Rundek, Mitchell S. V. Elkind, Elizabeth C. Oelsner, R. Graham Barr, Iuliana Ionita-Laza, Jan Novak, Ali G. Gharavi, Krzysztof Kiryluk
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Immunoglobulin A protects against infectious disease and contributes to autoimmune and inflammatory disorders. Here, the authors perform a genome-wide association study for serum IgA levels, identifying 20 genome-wide significant loci, providing new
Externí odkaz:
https://doaj.org/article/a56e340c9bb948a69e4eb08fc8a4c941
Autor:
John B Harley, Viktoryia Laurynenka, Kenneth M Kaufman, Dennis H Clark, Iouri Chepelev, Isaac TW Harley
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ead882b149cd47758512143962f7e790
Autor:
Tian Zhou, Xinyi Zhu, Zhizhong Ye, Yong-Fei Wang, Chao Yao, Ning Xu, Mi Zhou, Jianyang Ma, Yuting Qin, Yiwei Shen, Yuanjia Tang, Zhihua Yin, Hong Xu, Yutong Zhang, Xiaoli Zang, Huihua Ding, Wanling Yang, Ya Guo, John B. Harley, Bahram Namjou, Kenneth M. Kaufman, Leah C. Kottyan, Matthew T. Weirauch, Guojun Hou, Nan Shen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The functional effects of genetic loci associated with autoimmune disease are not well understood. By dissecting an autoimmune disease genetic locus, the authors define an immune cell-type-specific enhancer and the molecular mechanisms underlying the
Externí odkaz:
https://doaj.org/article/b834bed781e544609a560d62e4f3795e
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/862fc49caa3b44738e41013affe9889a
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/1fa1b095906243598876aec100690634
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
A major goal of genetics research is to elucidate mechanisms explaining how genetic variation contributes to phenotypic variation. The genetic variants identified in genome-wide association studies (GWASs) generally explain only a small proportion of
Externí odkaz:
https://doaj.org/article/dd041971c2394d2ab5f83d0c3eb48caa
Autor:
Xiaoming Lu, Xiaoting Chen, Carmy Forney, Omer Donmez, Daniel Miller, Sreeja Parameswaran, Ted Hong, Yongbo Huang, Mario Pujato, Tareian Cazares, Emily R. Miraldi, John P. Ray, Carl G. de Boer, John B. Harley, Matthew T. Weirauch, Leah C. Kottyan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Thousands of genetic variants have been associated with lupus, but causal variants and mechanisms are unknown. Here, the authors combine a massively parallel reporter assay with genome-wide ChIP experiments to identify risk variants with allelic enha
Externí odkaz:
https://doaj.org/article/aad49cc516be41898af7df55bb543c1e