Zobrazeno 1 - 10
of 507
pro vyhledávání: '"John B, Davis"'
Autor:
Juliane Obst, Hazel L. Hall-Roberts, Thomas B. Smith, Mira Kreuzer, Lorenza Magno, Elena Di Daniel, John B. Davis, Emma Mead
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Human genetic studies have linked rare coding variants in microglial genes, such as TREM2, and more recently PLCG2 to Alzheimer’s disease (AD) pathology. The P522R variant in PLCG2 has been shown to confer protection for AD and to result i
Externí odkaz:
https://doaj.org/article/1c7337e110a44e7892c77769f789ed8a
Autor:
Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Gary Tresadern, Paul E. Brennan, John B. Davis, Daniel Ebner, Elena Di Daniel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Inhibition of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome has recently emerged as a promising therapeutic target for several inflammatory diseases. After priming and activation by inflammation triggers, NLRP3 for
Externí odkaz:
https://doaj.org/article/1fa617be6c444588bad302d2d3607a84
Autor:
John B. Davis
This book examines the different conceptions of the individual that have emerged in recent new approaches in economics, including behavioral economics, experimental economics, social preferences approaches, game theory, neuroeconomics, evolutionary a
Autor:
Hazel Hall-Roberts, Devika Agarwal, Juliane Obst, Thomas B. Smith, Jimena Monzón-Sandoval, Elena Di Daniel, Caleb Webber, William S. James, Emma Mead, John B. Davis, Sally A. Cowley
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-27 (2020)
Abstract Background TREM2 is a microglial cell surface receptor, with risk mutations linked to Alzheimer’s disease (AD), including R47H. TREM2 signalling via SYK aids phagocytosis, chemotaxis, survival, and changes to microglial activation state. I
Externí odkaz:
https://doaj.org/article/7003790f6cc94c199bdb2b9d9a1caf4d
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0232644 (2020)
When trying to identify new potential therapeutic protein targets, access to data and knowledge is increasingly important. In a field where new resources and data sources become available every day, it is crucial to be able to take a step back and lo
Externí odkaz:
https://doaj.org/article/6d4e15cafb6d4933858ad78b832e3499
Autor:
John B. Davis
Publikováno v:
Œconomia, Vol 8, Iss 4, Pp 509-529 (2018)
This paper argues that agent-based modeling’s innovations in method developed in terms of simulation techniques also involve an improvement in economic methodology. It shows how Epstein’s generative science conception can be seen as departing fro
Externí odkaz:
https://doaj.org/article/13fd01e9eac240a08faa9a3b6d9c17a5
Autor:
Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Gary Tresadern, Paul E. Brennan, John B. Davis, Daniel Ebner, Elena Di Daniel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/87b5d1c433174420bb315595d76f8e3d
Publikováno v:
Frontiers in Marine Science, Vol 6 (2019)
To safeguard biodiversity effectively, marine protected areas (MPAs) should be sited using the best available science. There are numerous ongoing United Nations and non-governmental initiatives to map globally important marine areas. The criteria use
Externí odkaz:
https://doaj.org/article/2d105b05710e4417b1d40c613293de96
Autor:
John B. Davis
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dff12a7fee0d19c408d15386cdc5692
https://doi.org/10.2139/ssrn.4463743
https://doi.org/10.2139/ssrn.4463743
Autor:
John B. Davis
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6b9b38f7de5e07c4cfb8b8e10aab22
https://doi.org/10.2139/ssrn.4378169
https://doi.org/10.2139/ssrn.4378169