Zobrazeno 1 - 10
of 10
pro vyhledávání: '"John Avera"'
Autor:
Kelly M. Shepardson, Benjamin Schwarz, Kyle Larson, Rachelle V. Morton, John Avera, Kimberly McCoy, Alayna Caffrey, Ann Harmsen, Trevor Douglas, Agnieszka Rynda-Apple
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/c0d0e91da9d0443183322e9c08973f4a
Autor:
Kelly M. Shepardson, Benjamin Schwarz, Kyle Larson, Rachelle V. Morton, John Avera, Kimberly McCoy, Alayna Caffrey, Ann Harmsen, Trevor Douglas, Agnieszka Rynda-Apple
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Although viruses and viral capsids induce rapid immune responses, little is known about viral pathogen-associated molecular patterns (PAMPs) that are exhibited on their surface. Here, we demonstrate that the repeating protein subunit pattern
Externí odkaz:
https://doaj.org/article/bf3aeed89b554e81bd3b7e859806801e
Autor:
Agnieszka Rynda-Apple, Laura L. Johns, Jhanvi Sharma, Julia Wellham, Trevor Douglas, Kelly M. Shepardson, Benjamin Schwarz, John Avera
Publikováno v:
ACS Applied Materials & Interfaces
The continuous evolution of influenza A virus (IAV) requires the influenza vaccine formulations to be updated annually to provide adequate protection. Recombinant protein-based vaccines provide safer, faster, and a more scalable alternative to the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5b560607afde60370ff25a1a779ce9
https://doi.org/10.1021/acsami.9b21776
https://doi.org/10.1021/acsami.9b21776
Autor:
Heini M. Miettinen, John Avera, Trevor Douglas, Benjamin Schwarz, Joseph Che Yen Wang, Cheri Peyton Goodall, Ekaterina Selivanovitch
Publikováno v:
ACS Appl Bio Mater
Ligands of the tumor necrosis factor superfamily (TNFSF) are appealing targets for immunotherapy research due to their integral involvement in stimulation or restriction of immune responses. TNFSF-targeted therapies are currently being developed to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ad0aa83378a4cb55828943e7d06984
https://pubmed.ncbi.nlm.nih.gov/35005938
https://pubmed.ncbi.nlm.nih.gov/35005938
Autor:
EJun Yun, Bruce A. Molitoris, Ruben M. Sandoval, Amy Zollman, Bernhard F. Maier, Takashi Hato, John Avera, Masaki Uchida, Trevor Douglas, S. Louise Pay, Ekaterina Selivanovitch, Hitesh Kumar Waghwani
Nature exploits cage-like proteins for a variety of biological purposes, from molecular packaging and cargo delivery to catalysis. These cage-like proteins are of immense importance in nanomedicine due to their propensity to self-assemble from simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00f15de350966229e64233c11c773f4
https://europepmc.org/articles/PMC6715384/
https://europepmc.org/articles/PMC6715384/
Autor:
Agnieszka Rynda-Apple, Heini M. Miettinen, John Avera, Patrick Madden, Gautam Basu, Kyle Larson, Trevor Douglas, Masaki Uchida, Ben LaFrance, Benjamin Schwarz, Bridget Gordon
Publikováno v:
ACS Nano. 9:9134-9147
Viruses use spatial control of constituent proteins as a means of manipulating and evading host immune systems. Similarly, precise spatial control of proteins encapsulated or presented on designed nanoparticles has the potential to biomimetically amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b579bc6283f413ba11679fd4f280e66
https://doi.org/10.1021/acsnano.5b03360
https://doi.org/10.1021/acsnano.5b03360
Autor:
Dustin P. Patterson, Matthew Hicks, Matthew Terra, Brian Western, Masaki Uchida, Kimberly McCoy, John Avera, Paul Krugler, Trevor Douglas, Benjamin Schwarz
Virus-like particles are unique platforms well suited for the construction of nanomaterials with broad-range applications. The research presented here describes the development of a modular approach for the covalent attachment of protein domains to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31052e7b19753e2e093e9049b1343093
https://europepmc.org/articles/PMC6708598/
https://europepmc.org/articles/PMC6708598/
Autor:
Aida Llauró, Benes L. Trus, José R. Castón, John Avera, Daniel Luque, Pedro J. de Pablo, David Reguera, Ethan Edwards, Trevor Douglas
Nucleic acids are the natural cargo of viruses and key determinants that affect viral shell stability. In some cases the genome structurally reinforces the shell, whereas in others genome packaging causes internal pressure that can induce destabiliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fb47f6257dff9692b171a7260bcb26
https://europepmc.org/articles/PMC4861311/
https://europepmc.org/articles/PMC4861311/
Autor:
John Avera, Heini M. Miettinen, Tracy J. Ruckwardt, Trevor Douglas, Barney S. Graham, Dustin P. Patterson, Benjamin Schwarz, Kaitlyn M. Morabito
Subunit vaccines provide a safe, focused alternative to conventional vaccines. However, these vaccines often require significant adjuvants and are particularly hard to target toward cytotoxic T lymphocyte (CTL) immunity. Viruslike particles (VLPs) pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9eb7d423af1ffaf6923b0eacb9102a3
https://europepmc.org/articles/PMC5777520/
https://europepmc.org/articles/PMC5777520/
Publikováno v:
Southern medical journal. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994684ad4e17bf7a168365c973c98799
https://pubmed.ncbi.nlm.nih.gov/21014951
https://pubmed.ncbi.nlm.nih.gov/21014951